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ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:34 PM EST

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Showing 121–144 of 3,978 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pathophysiology Clear all
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Aortic Stenosis - B.A.S.S.

NCT01334801
View directory record Official record
Conditions
Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency
Interventions
Blood Draw
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
378 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Nov 7, 2026, 5:34 PM EST
Completed Early Phase 1 Interventional Accepts healthy volunteers

Differing Levels of Hypoglycemia

NCT02445781
View directory record Official record
Conditions
Hypoglycemia
Interventions
Glucose clamp
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 6, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Not listed Not applicable Interventional

Kinematic and Kinetic Effects of Orthotic Devices for Subjects With Stage II Posterior Tibial Tendon Dysfunction

NCT01749657
View directory record Official record
Conditions
Posterior Tibial Tendon Dysfunction
Interventions
Arizona
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2014 · Synced Nov 7, 2026, 5:34 PM EST
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

IT Matters: The Erectile Restoration Registry

NCT04200937
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis, AMS 700™ Inflatable Penile Prosthesis w/Momentary Squeeze (MS) Pump, AMS 700™ Inflatable Penile Prosthesis w/Tenacio™ Pump
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older · Male only
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2031
U.S. locations
21
States / cities
Los Angeles, California • Miami, Florida • Tampa, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Completed No phase listed Observational

An Evaluation of Psychological Parameters That May Influence the Outcome Following Arthroscopy and Arthroplasty for Temporomandibular Joint Surgery

NCT01396694
View directory record Official record
Conditions
Psychological Predictors
Interventions
Questionnaire
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 90 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Nov 7, 2026, 5:34 PM EST
Completed Not applicable Interventional

Mitigating Post-Op RV Dysfunction After LVAD Implantation

NCT05758194
View directory record Official record
Conditions
Heart Failure, Right Ventricular Dysfunction, Right Ventricular Failure
Interventions
Standardized RV Management, Usual Care RV Management
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Nov 7, 2026, 5:34 PM EST
Completed No phase listed Observational

Quality Improvement PrecivityAD Clinician Survey (QUIP I)

NCT05477056
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline
Interventions
PrecivityAD blood test
Other
Lead sponsor
C2N Diagnostics
Industry
Eligibility
60 Years and older
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Nov 7, 2026, 5:34 PM EST
Completed Not applicable Interventional

Brief Treatment for Temporomandibular Pain

NCT00067366
View directory record Official record
Conditions
Temporomandibular Joint Syndrome, Myofascial Pain Dysfunction Syndrome, Orofacial Pain
Interventions
Cognitive-Behavioral treatment, Attention and lifestyle counseling
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Nov 7, 2026, 5:34 PM EST
Completed Phase 2 Interventional Results available

Trial of Mesna to Prevent Doxorubicin-induced Plasma Protein Oxidation and Tumor Necrosis Factor Alpha (TNF-α) Release

NCT01205503
View directory record Official record
Conditions
Breast Cancer, Non-Hodgkin's Lymphoma
Interventions
Mesna, Saline, Doxorubicin, Cyclophosphamide
Drug
Lead sponsor
Mara Chambers
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Nov 7, 2026, 5:34 PM EST
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Tfh Dysfunction in HIV and Aging

NCT04487041
View directory record Official record
Conditions
Human Influenza
Interventions
Standard dose influenza vaccination, High dose influenza vaccination
Biological
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Recruiting Not applicable Interventional

Working Memory Training in Patients with Mild Cognitive Impairment

NCT06734286
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
CogMed
Other
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Nov 7, 2026, 5:34 PM EST
Recruiting Phase 3 Interventional

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

NCT06318169
View directory record Official record
Conditions
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Interventions
Pegozafermin, Placebo
Biological · Other
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
154
States / cities
Birmingham, Alabama • Chandler, Arizona • Flagstaff, Arizona + 132 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Recruiting Not applicable Interventional

Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

NCT07485231
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Trauma
Interventions
Beetroot Juice, Placebo Juice
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Completed Phase 3 Interventional

Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

NCT00241722
View directory record Official record
Conditions
Bowel Dysfunction, Constipation
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
805 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
143
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 120 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Nov 7, 2026, 5:34 PM EST
Recruiting Not applicable Interventional

Treating Insomnia in Mild Cognitive Impairment

NCT06687161
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Insomnia, Subjective Cognitive Decline (SCD)
Interventions
Transcranial Magnetic Stimulation (TMS) therapy, Cognitive behavioral therapy for insomnia (CBT-I)
Device · Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Not listed Not applicable Interventional

STP.168 Clinical Study Protocol Parakeet

NCT06499142
View directory record Official record
Conditions
Parathyroid; Anomaly, Parathyroid Dysfunction, Hyperparathyroidism, Parathyroid Gland Adenoma
Interventions
Parakeet:The Parakeet Rapid Parathyroid Testing Kit is a rapid immunoassay designed to detect Parathormone (PTH) in a test sample.
Device
Lead sponsor
Neurovision Medical Products Inc
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Nov 7, 2026, 5:34 PM EST
Recruiting Not applicable Interventional

Music for Pain and Dementia

NCT07602283
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Mild Cognitive Impairment, Peer-bonded Caregiver, Caregiver
Interventions
Drumming session, Music-listening session
Behavioral
Lead sponsor
Yale University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Completed Phase 2 Interventional Results available

Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia

NCT00588731
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Nov 7, 2026, 5:34 PM EST
Recruiting Phase 4 Interventional

The STOP-MED CTRCD Trial

NCT06183437
View directory record Official record
Conditions
Heart Failure, Cardiotoxicity, Cardiac Toxicity, Antineoplastics Toxicity, Cancer
Interventions
Stopping Heart Failure Medication(s)
Other
Lead sponsor
Dinesh Thavendiranathan
Other
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
2
States / cities
Los Angeles, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Not yet recruiting Phase 2 Interventional

Effects of Tadalafil on Cognition and Cerebral Hemodynamics in Elderly Patients With Mild Cognitive Impairment

NCT07882901
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Tadalafil 5 mg
Drug
Lead sponsor
Los Angeles Brain Science Project
Other
Eligibility
60 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Nov 7, 2026, 5:34 PM EST
Withdrawn No phase listed Observational

Catheter Ablation for Atrial Fibrillation and Heart Failure

NCT01082601
View directory record Official record
Conditions
Congestive Heart Failure, Atrial Fibrillation, Arrhythmia
Interventions
Pulmonary Vein Isolation (PVI)
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Ridgewood, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2012 · Synced Nov 7, 2026, 5:34 PM EST
Completed Phase 2 Interventional Results available

An Open Label Trial of Bupropion and Naltrexone for Binge Drinking

NCT02842073
View directory record Official record
Conditions
Binge Drinking
Interventions
Naltrexone, Bupropion
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years to 34 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Nov 7, 2026, 5:34 PM EST
Completed Phase 1 Interventional Results available

Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction

NCT00145041
View directory record Official record
Conditions
Malignant Melanoma
Interventions
Vincristine Sulfate Liposomes Injection
Drug
Lead sponsor
Acrotech Biopharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Nov 7, 2026, 5:34 PM EST
Completed Not applicable Interventional

Pomegranate and Hemodialysis Pilot Trial

NCT01562340
View directory record Official record
Conditions
End Stage Renal Disease, Cardiovascular Disease, Inflammation
Interventions
Pomegranate juice, Pomegranate fruit extract
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Nov 7, 2026, 5:34 PM EST