Independent directory Public ClinicalTrials.gov records United States
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Showing 649–672 of 819 matching trials from the live ClinicalTrials.gov search.
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Conditions
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
Interventions
Not listed
Lead sponsor
Indivi AG
Industry
Eligibility
50 Years to 90 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
Interventions
BIO101, Placebo
Drug
Lead sponsor
Biophytis
Industry
Eligibility
65 Years and older
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
19
States / cities
Banning, California • Garden Grove, California • San Diego, California + 15 more
Conditions
Presbyopia
Interventions
LD118033 contact lens, PureVision multifocal contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Recruiting No phase listed Observational Accepts healthy volunteers

The DistaSense VITALS Study

NCT07217327
Conditions
Detection of Heart Rate and Respiratory Rate
Interventions
DistaSense and Polysomnography
Diagnostic Test
Lead sponsor
Life Detection Technologies
Industry
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
St Louis, Missouri • Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Blood Glucose Monitoring Systems With Blood Samples From Neonates

NCT01756274
Conditions
Diabetes
Interventions
Contour® NEXT BGMS, Contour® PLUS BGMS, Contour® Next EZ BGMS
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
Up to 30 Days
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT05933772
Conditions
Astigmatism
Interventions
Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Pittsburg, Kansas • Vestal, New York • Granville, Ohio
Conditions
Wound
Interventions
Standard care
Other
Lead sponsor
Woundchek Laboratories BV
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Salem, Virginia
Not listed Not applicable Interventional Accepts healthy volunteers

Performance Assessment Study VitalSigns Camera

NCT05465018
Conditions
Healthy Humans, Vital Signs Monitoring
Interventions
Happy Flow / Baseline, Make-up, Sunglasses, Face mask, Minimum requirements camera, Worst case hardware, Damaged lens, Face or chest outside test frame
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Breast Cancer
Interventions
Digital Mammography, Low Osmolar Contrast Material, 300-399 Mg/Ml Iodine Concentration, Per Ml
Procedure · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Muscle Damage
Interventions
Solarplast (R), Placebo
Dietary Supplement
Lead sponsor
Kent State University
Other
Eligibility
18 Years to 35 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kent, Ohio
Terminated Not applicable Interventional Results available

A Study to Compare Nighttime Aligners to Daytime Aligners

NCT06539676
Conditions
Teeth Straightening, Aligner Therapy, Orthodontic Aligner
Interventions
Nighttime Aligners, Daytime Aligners
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
12 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
Redondo Beach, California • Miami Beach, Florida • Towson, Maryland + 9 more
Conditions
Bladder Cancer
Interventions
ADXBLADDER
Diagnostic Test
Lead sponsor
Arquer Diagnostics Ltd
Industry
Eligibility
22 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
13
States / cities
Denver, Colorado • Daytona Beach, Florida • Jeffersonville, Indiana + 10 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Performance and Safety of Two Intradermal Delivery Devices.

NCT01943110
Conditions
Injections, Intradermal
Interventions
ID adapter (autodisable), ID adapter (side load)
Device
Lead sponsor
PATH
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Renton, Washington
Conditions
Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
Interventions
Exercise + SOC PT/OT, SOC PT/OT
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
7 Years to 60 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
4
States / cities
Davis, California • Dallas, Texas • Galveston, Texas + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of an Karajishi Contour Investigational Blood Glucose Monitoring System (ISO/FDA Study)

NCT02150109
Conditions
Diabetes
Interventions
Subjects WITH/WITHOUT Diabetes Use Karajishi Contour BGMS, Subjects WITH Diabetes Use Karajishi Contour BGMS
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Escondido, California • Renton, Washington
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Trial of Testosterone Undecanoate for Optimizing Performance During Military Operations

NCT04120363
Conditions
Caloric Restriction, Exercise, Sleep
Interventions
Testosterone Undecanoate, Sesame Oil
Drug
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Asthma
Interventions
Benralizumab
Biological
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 75 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
14
States / cities
Northridge, California • Riverside, California • Westminster, California + 11 more
Conditions
Peripheral Artery Disease, End Stage Renal Disease on Dialysis
Interventions
Not listed
Lead sponsor
Sanifit Therapeutics S. A.
Other
Eligibility
45 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Northridge, California • Coral Gables, Florida • Boston, Massachusetts + 3 more
Conditions
Carotid Artery Diseases, Aortic Diseases, Peripheral Arterial Diseases
Interventions
Intergard Standard - Collagen Coated Vascular Grafts and Patches, Hemashield - Collagen Coated Vascular Grafts and Patches, Intergard Silver - Antimicrobial Collagen Coated Vascular Grafts and Patches, Intergard Synergy - Antimicrobial Collagen Coated Vascular Grafts
Device
Lead sponsor
Intervascular
Industry
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Hershey, Pennsylvania • Pittsburgh, Pennsylvania
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Study to Assess the Performance of MagnEtOs Flex Matrix Compared to Cellular Allograft

NCT06415123
Conditions
Degenerative Disc Disease
Interventions
MagnetOs Flex Matrix
Device
Lead sponsor
Research Source
Network
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Southfield, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Impact of Vitrification on Oocytes

NCT01223118
Conditions
Fertilization
Interventions
Vitrification and PGD
Procedure
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 35 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Morristown, New Jersey • Allentown, Pennsylvania
Conditions
Tuberculosis
Interventions
T-Cell SelectTM Kit
Diagnostic Test
Lead sponsor
Oxford Immunotec
Industry
Eligibility
18 Years and older
Enrollment
680 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Fall River, Massachusetts • Columbus, Ohio • Brownsville, Texas
Conditions
Osteoarthritis
Interventions
ATTUNE Primary Total Knee Arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
22 Years to 80 Years
Enrollment
1,138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
9
States / cities
Orange, California • San Diego, California • Fort Collins, Colorado + 6 more