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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Periodontal Bone Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Implant-Abutment Interface Design on Bone and Soft Tissue Levels Around Implants Placed Using Different Transcrestal Sinus Floor Elevation

NCT02953392
View directory record Official record
Conditions
Tooth Loss
Interventions
Anorganic Bovine Bone Graft Material, Collagen Membrane, Shelta Platform Switching Premium Implants, Shelta Platform Matching Premium Implants
Device
Lead sponsor
NYU College of Dentistry
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials

NCT02802319
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Porcine Xenograft (Zcore), Bovine Xenograft (Bio-Oss)
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Jul 21, 2026, 10:16 PM EDT
Enrolling by invitation Not applicable Interventional

Ti-Mesh Frame Comparison for Alveolar Bone Augmentation

NCT06077513
View directory record Official record
Conditions
Tooth Loss
Interventions
CAD-CAM designed and preprinted Ti-Mesh frame, Conventional chairside fabrication of Ti-Mesh frame
Procedure
Lead sponsor
Boston University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bone Augmentation Techniques in Extraction Sockets

NCT01836783
View directory record Official record
Conditions
Tooth Loss
Interventions
Amnion Allograft, Allograft
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 9, 2024 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Not applicable Interventional Results available

GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery

NCT01728844
View directory record Official record
Conditions
Alveolar Bone Loss, Periodontal Diseases
Interventions
beta-tricalcium phosphate alone, GFeBGS 0.1%, GFeBGS 0.3%, GFeBGS 0.4%
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
25 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Birmingham, Alabama • Fullerton, California • Aurora, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Phase 1 Interventional

Impact of Parathyroid Hormone (PTH) on Osseous Cavity

NCT00277706
View directory record Official record
Conditions
Bone Loss, Periodontitis
Interventions
Periodontal surgery, FORTEO, Placebo, Vitamin D and Calcium
Procedure · Drug · Dietary Supplement
Lead sponsor
University of Michigan
Other
Eligibility
30 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2009 · Synced Jul 21, 2026, 10:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate Implant Outcomes With and Without Bone Augmentation

NCT05157009
View directory record Official record
Conditions
Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
Interventions
implant placement
Procedure
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Gabriel, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Early Phase 1 Interventional

Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients

NCT02972788
View directory record Official record
Conditions
Periodontal Bone Loss
Interventions
Enamel Matrix Proteins Derivative, Saline
Drug · Other
Lead sponsor
University of Nebraska
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Jul 21, 2026, 10:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Azento IIS 3 Year Outcomes Implant Study

NCT04255342
View directory record Official record
Conditions
Tooth Loss
Interventions
Implant Placement and Temporary Crown using AstraTech Implant System EV, Final Crown Delivery
Device
Lead sponsor
Christopher Barwacz
Other
Eligibility
18 Years to 95 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Jul 21, 2026, 10:16 PM EDT
Not listed No phase listed Observational

Accuracy of Extra-oral Bite-wing Radiography in Detecting Calculus and Crestal Bone Loss

NCT05887128
View directory record Official record
Conditions
Periodontitis, Calculus, Dental, Bone Loss, Alveolar
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Short Dental Implants (5 mm) Versus Long Dental Implants (10 mm)

NCT04144322
View directory record Official record
Conditions
Bone Loss, Alveolar
Interventions
Zimmer T3 Short Ex Hex With Discrete Crystalline Deposition, Zimmer T3 with Discrete Crystalline Deposition Ex Hex Parallel Walled implants
Device
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Jul 21, 2026, 10:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft

NCT04550689
View directory record Official record
Conditions
Tooth Loss
Interventions
Bone graft
Device
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Jul 21, 2026, 10:16 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation

NCT03943849
View directory record Official record
Conditions
Tooth Loss
Interventions
Particulate bone graft, Autogenous dental pulp tissue, Resorbable collagen membrane, Suture
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation

NCT00980278
View directory record Official record
Conditions
Tooth Loss
Interventions
Sinus lift augmentation and dental implant, Aastrom BRCs
Procedure · Biological
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 22, 2015 · Synced Jul 21, 2026, 10:16 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Effect of Actonel on Periodontal Health of Postmenopausal Women

NCT00594334
View directory record Official record
Conditions
Periodontal Disease
Interventions
Risedronate
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
40 Years to 80 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Jul 21, 2026, 10:16 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Ultrasound for Socket Healing Evaluation

NCT06017193
View directory record Official record
Conditions
Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image, Dent Disease
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Jul 21, 2026, 10:16 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization

NCT05932017
View directory record Official record
Conditions
Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation, Periodontal Attachment Loss, Periodontal Bone Loss, Surgery
Interventions
Not listed
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Not applicable Interventional Results available

Bone Level Tapered Multi-Center Study

NCT02569671
View directory record Official record
Conditions
Tooth Loss
Interventions
Straumann Bone Level Tapered Implant - Immediate Placement, Straumann Bone Level Tapered Implant - Delayed Placement
Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
3
States / cities
Los Angeles, California • Gainesville, Florida • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

NCT03659617
View directory record Official record
Conditions
Tooth Loss
Interventions
xenograft (BioOss Collagen)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Phase 4 Interventional

The Influence of Dimensional Anatomic Variables on the Outcomes of Maxillary Sinus Grafting Procedures

NCT00868777
View directory record Official record
Conditions
Edentulism, Alveolar Bone Atrophy, Sinus Pneumatization
Interventions
Sinus grafting using allogenic bone
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 24, 2009 · Synced Jul 21, 2026, 10:16 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy

NCT00755911
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Tissue Repair Cells (TRC), Control
Biological · Device
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2015 · Synced Jul 21, 2026, 10:16 PM EDT
Terminated No phase listed Observational

Localized Alveolar Ridge Augmentation With Space Maintenance Devices

NCT00991432
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
8
States / cities
Los Angeles, California • Greenwood Village, Colorado • Sarasota, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Jul 21, 2026, 10:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Zirconia Implants: Practice-based Evidence

NCT06314425
View directory record Official record
Conditions
Dental Implants, Ceramic Implant
Interventions
Immediate dental implants placements on fresh sockets after tooth extraction
Procedure
Lead sponsor
Swiss Dental Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Englewood Cliffs, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Jul 21, 2026, 10:16 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)

NCT03657589
View directory record Official record
Conditions
Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Jul 21, 2026, 10:16 PM EDT