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ClinicalTrials.gov public records Last synced Jun 26, 2026, 6:17 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Peripheral Artery Occlusive Disease Clear all
Recruiting Not applicable Interventional

Real-World Registry of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)

NCT07016698
View directory record Official record
Conditions
Peripheral Arterial Disease(PAD)
Interventions
Rotarex(TM) Rotational Excisional Atherectomy System
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
22 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Lakeland, Florida • Humble, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Not applicable Interventional

Personalized Cardiovascular Risk Information to Initiate and Maintain Health Behavior Changes

NCT01134458
View directory record Official record
Conditions
Cardiovascular Disease, Peripheral Artery Disease, Ischemic Stroke, Diabetes
Interventions
Web-Based Intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 1 Interventional

EW-A-401 to Treat Intermittent Claudication

NCT00080392
View directory record Official record
Conditions
Intermittent Claudication, Arteriosclerosis
Interventions
DNA Plasmid Vector, EW-A-401 DNA Plasmid Vector
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
3
States / cities
Birmingham, Alabama • Bethesda, Maryland • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 1 Interventional

Natural Vascular Scaffold (NVS) Therapy

NCT03148808
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases, Catheterization, Peripheral
Interventions
NVS Therapy
Combination Product
Lead sponsor
Alucent Biomedical
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Columbus, Ohio • Wynnewood, Pennsylvania • Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Jun 26, 2026, 6:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening and Access to Health Care for Vascular Disease

NCT01889485
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal, Carotid Stenosis, Peripheral Arterial Disease
Interventions
Not listed
Lead sponsor
Endeavor Health
Other
Eligibility
55 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

NCT01064440
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Low Dose VM202, High Dose VM202, Placebo
Biological · Other
Lead sponsor
Helixmith Co., Ltd.
Industry
Eligibility
18 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
13
States / cities
Birmingham, Alabama • Orange, California • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jun 26, 2026, 6:17 PM EDT
Completed No phase listed Observational Results available

Radial accEss for nAvigation to Your CHosen Lesion for Peripheral Vascular Intervention: REACH PVI

NCT03943160
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Diamondback 360 Extended Length Orbital Atherectomy System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
6
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Lafayette, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Jun 26, 2026, 6:17 PM EDT
Recruiting No phase listed Observational

Pounce™ Thrombectomy System Retrospective Registry

NCT05868161
View directory record Official record
Conditions
Peripheral Arterial Disease, Acute Limb Ischemia
Interventions
Pounce Thrombectomy System
Device
Lead sponsor
SurModics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
9
States / cities
Peoria, Illinois • Munster, Indiana • Baton Rouge, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Jun 26, 2026, 6:17 PM EDT
Completed No phase listed Observational Results available

Non-invasive Computer-Aided Phenotyping of Vasculopathy

NCT02143102
View directory record Official record
Conditions
Carotid Atherosclerosis, Peripheral Arterial Disease
Interventions
Not listed
Lead sponsor
Elucid Bioimaging Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Marrero, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced Jun 26, 2026, 6:17 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Onsite Tobacco Cessation Treatment for Patients With PAD

NCT05469698
View directory record Official record
Conditions
Tobacco Cessation, Peripheral Artery Disease
Interventions
Tobacco Treatment Research Program Standard Care
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Jun 26, 2026, 6:17 PM EDT
Not listed Phase 2 Interventional

Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease

NCT00053716
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Liprostin [liposomal Prostaglandin E1]
Drug
Lead sponsor
Endovasc
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2007 · Synced Jun 26, 2026, 6:17 PM EDT
Recruiting Phase 2 Interventional

Passive Stretching in Peripheral Arterial Disease Patients

NCT06420752
View directory record Official record
Conditions
Peripheral Arterial Disease, Walking, Difficulty, Inflammation
Interventions
Calf Plantar flexion, Dietary nitrate
Device · Dietary Supplement
Lead sponsor
University of Wisconsin, La Crosse
Other
Eligibility
40 Years to 90 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 2 Interventional

Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease

NCT00113009
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
VLTS-934
Drug
Lead sponsor
Valentis
Industry
Eligibility
40 Years to 78 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
32
States / cities
Birmingham, Alabama • Beverly Hills, California • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2007 · Synced Jun 26, 2026, 6:17 PM EDT
No Longer Available No phase listed Expanded access

Safety and Efficacy of Autologous Concentrated Bone Marrow Aspirate for Critical Limb Ischemia - Continued Access

NCT02474121
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases, Critical Limb Ischemia
Interventions
Bone marrow concentration device
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
21 Years and older
U.S. locations
9
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Indianapolis, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Jun 26, 2026, 6:17 PM EDT
Completed No phase listed Observational

FLEX Arteriovenous Access Registry

NCT04070365
View directory record Official record
Conditions
Peripheral Artery Disease, Arteriovenous Fistula Stenosis, Arteriovenous Graft Stenosis
Interventions
FLEX Vessel Prep System followed by angioplasty
Device
Lead sponsor
VentureMed Group Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
10
States / cities
Birmingham, Alabama • Dothan, Alabama • Tuscaloosa, Alabama + 7 more
Source: ClinicalTrials.gov public record
Updated May 30, 2022 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Not applicable Interventional

Ischemic Preconditioning Claudication Study

NCT03511157
View directory record Official record
Conditions
Intermittent Claudication, Ischemia Vascular, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions
Ischemic Preconditioning, Control Group
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Not applicable Interventional Results available

GORE VIABAHN Endoprosthesis With Heparin Bioactive Surface in the Treatment of SFA Obstructive Disease (VIPER)

NCT00541307
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
Treatment with the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Oceanside, California • Chicago, Illinois • Columbia, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2012 · Synced Jun 26, 2026, 6:17 PM EDT
Recruiting Phase 4 Interventional

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

NCT02915198
View directory record Official record
Conditions
Prediabetic State, Atherosclerosis, Metformin
Interventions
Metformin XR, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
7,410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
40
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 37 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 3 Interventional Results available

A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes

NCT04560998
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Peripheral Arterial Disease
Interventions
Semaglutide, Placebo (semaglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
792 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
88
States / cities
Birmingham, Alabama • Chandler, Arizona • Glendale, Arizona + 64 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 2 Interventional Results available

OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO

NCT02819011
View directory record Official record
Conditions
Accidental Falls, Fall Due to Loss of Equilibrium, High Risk of Falls Due to Mobility Limitation, Diabetes, Arthritis, Cancer, Peripheral Arterial Disease, Parkinson's Disease, End Stage Renal Failure on Dialysis
Interventions
MBB AFO, Control
Device · Other
Lead sponsor
Bijan Najafi, PhD
Other
Eligibility
65 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2020 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Phase 3 Interventional Results available

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

NCT01732822
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Ticagrelor, Clopidogrel
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
50 Years to 130 Years
Enrollment
13,885 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
290
States / cities
Alexander City, Alabama • Auburn, Alabama • Birmingham, Alabama + 239 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2017 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Not applicable Interventional Results available

A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.

NCT05145439
View directory record Official record
Conditions
Diabetic Foot Ulcer, Peripheral Arterial Disease, Wound; Foot
Interventions
VibratoSleeve Therapeutic Ultrasound Device
Device
Lead sponsor
Vibrato Medical, Inc.
Industry
Eligibility
22 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Jun 26, 2026, 6:17 PM EDT
Completed Not applicable Interventional

The Use of Fish Oil to Reduce Inflammation Caused by a Peripheral Vascular Intervention

NCT02096757
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Pro-Omega, Pro-Omega Placebo
Dietary Supplement · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Jun 26, 2026, 6:17 PM EDT
Active, not recruiting Phase 3 Interventional

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT06383390
View directory record Official record
Conditions
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
Interventions
Retatrutide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
205
States / cities
Alabaster, Alabama • Birmingham, Alabama • Daphne, Alabama + 158 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jun 26, 2026, 6:17 PM EDT