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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post-Operative Ileus Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Implementing a Low Fiber Diet vs. Regular Diet in Postoperative Colorectal Patients With Ileostomies

NCT04675606
View directory record Official record
Conditions
Ileostomy; Complications, Bowel Obstruction, Postoperative Ileus
Interventions
Regular diet, Low fiber diet
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy

NCT00708201
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
20
States / cities
Laguna Hills, California • Aurora, Colorado • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 3 Interventional

Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus

NCT00205842
View directory record Official record
Conditions
Ileus
Interventions
alvimopan
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Exton, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 10, 2016 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of TU-100 on Gastrointestinal and Colonic Transit in Humans

NCT00871325
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Daikenchuto (TU-100), Placebo
Drug
Lead sponsor
Tsumura USA
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 13, 2013 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 2 Interventional Results available

Effect of TU-100 in Patients Undergoing Laparoscopic Colectomy

NCT02232893
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Daikenchuto (TU-100), Placebo
Drug
Lead sponsor
Tsumura USA
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
13
States / cities
Los Angeles, California • Aurora, Colorado • Weston, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed No phase listed Observational

Predictive Validity of Acoustic Gastrointestinal Surveillance (AGIS) in Post-Operative Feeding

NCT02065583
View directory record Official record
Conditions
Post Operative Ileus
Interventions
Not listed
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2015 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

Alvimopan as a Rescue Treatment of Postoperative Ileus

NCT04405037
View directory record Official record
Conditions
Ileus, Gastrointestinal Dysfunction
Interventions
Alvimopan
Drug
Lead sponsor
Scott Steele
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed No phase listed Observational

G-Tech Feasibility Study for Early Detection of a Post-op Ileus

NCT02673671
View directory record Official record
Conditions
Post-operative Ileus
Interventions
G-Tech Myoelectric recording device
Device
Lead sponsor
G-Tech Corporation
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated Phase 4 Interventional Results available

Nicotine Gum Recovery After Colorectal Surgery

NCT01662115
View directory record Official record
Conditions
Post-operative Ileus
Interventions
Nicotine gum, Regular chewing gum
Drug · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 1 Interventional

Rocking Motion: Physiologic Effect on the Surgical Stress Response

NCT01200316
View directory record Official record
Conditions
Gastrointestinal Cancer
Interventions
Standard of Care, Rocking Chair Motion, Questionnaire
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Acupuncture and Post-Operative Ileus

NCT00655317
View directory record Official record
Conditions
Ileus
Interventions
Acupuncture, Sham acupuncture
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2011 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated Phase 4 Interventional Results available

Effect of Ketamine on Postoperative Clinical Outcomes

NCT01365195
View directory record Official record
Conditions
Colorectal Surgery
Interventions
Placebo, Ketamine high-dose, Ketamine low-dose
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed Phase 4 Interventional

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

NCT02958566
View directory record Official record
Conditions
Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis, Pain, Postoperative, Ileus, Ileus Paralytic, Ileus; Mechanical, Constipation Drug Induced, Constipation, Rectum Cancer, Rectum Neoplasm
Interventions
Acetaminophen, Gabapentin, Orphenadrine, Lidocaine, Marcaine, Ketamine, Methadone, Tramadol, Ketorolac, Morphine Sulfate, Fentanyl, Dilaudid, Hydrocodone-Acetaminophen Tab 5-325 MG, HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
Drug
Lead sponsor
University of Illinois College of Medicine at Peoria
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Withdrawn Not applicable Interventional

Caffeinated Gum to Prevent Post-Operative Ileus: A Prospective, Randomized, Placebo-controlled Trial

NCT02250924
View directory record Official record
Conditions
C.Surgical Procedure; Digestive System
Interventions
Caffeine, Gum, wear silicone bracelet
Dietary Supplement · Other · Behavioral
Lead sponsor
The Guthrie Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Sayre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated Phase 3 Interventional Results available

Alvimopan as Rescue in Post op Ileus

NCT02742181
View directory record Official record
Conditions
Colorectal Surgery, Ileus
Interventions
Alvimopan, Control Group
Drug · Other
Lead sponsor
Sharon Stein
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 2 Interventional

Trial of Acupuncture for Reduction of Post-Colectomy Ileus

NCT00402961
View directory record Official record
Conditions
Postoperative Ileus, Colon Cancer, Pain, Postoperative, Postoperative Nausea and Vomiting
Interventions
Acupuncture, Sham Acupuncture
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2015 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed Not applicable Interventional

Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment

NCT04880473
View directory record Official record
Conditions
Gastrointestinal Complication
Interventions
PrevisEA device
Device
Lead sponsor
Entac Medical Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
8
States / cities
Orlando, Florida • Chicago, Illinois • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 3 Interventional Results available

A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair

NCT00528970
View directory record Official record
Conditions
Ileus
Interventions
MOA-728, Placebo
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years and older
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
75
States / cities
Benton, Arkansas • Colton, California • Laguna Hills, California + 62 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2019 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional

The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.

NCT02639728
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Regular Coffee, Decaffeinated coffee, Warm water
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Recruiting Not applicable Interventional

Low Pressure Pneumoperitoneum and Postoperative Ileus

NCT05344417
View directory record Official record
Conditions
Postoperative Ileus, Gastrointestinal Dysfunction
Interventions
Pneumoperitoneum Pressure, Neuromuscular blockade, Pneumoperitoneum insufflation device, Neuromuscular blockade reversal
Procedure · Device · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Nasogastric Decompression Following Pancreaticoduodenectomy

NCT06413888
View directory record Official record
Conditions
Pancreatic Head Neoplasm, Delayed Gastric Emptying, Post Operative Ileus, Whipple Procedure
Interventions
pancreaticoduodenectomy
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Jul 22, 2026, 2:08 PM EDT
Withdrawn Not applicable Interventional

The Effect of Gum Chewing on Postoperative Ileus

NCT00879294
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
Motion sickness wristband, Chewing Gum
Device · Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
6 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed Not applicable Interventional

Use of Pedometer Following Radical Cystectomy

NCT04305730
View directory record Official record
Conditions
Bladder Cancer, Ileus, Narcotic Use
Interventions
Use of a pedometer following surgery, Standard of care
Behavioral
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional

The Effect of Coffee After Resection of Small Bowel

NCT03143621
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Coffee, Water
Dietary Supplement · Other
Lead sponsor
Mount Carmel Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Jul 22, 2026, 2:08 PM EDT