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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:22 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Pain After Surgery, Anxiety After Surgery
Interventions: Mindfulness Intervention; Behavioral
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage, Postoperative Pain, Ketorolac Adverse Reaction, Blood Loss, Postoperative
Interventions: Ketorolac Tromethamine 30 MG/ML, Placebos; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation, Duration of Response, Narcotics Consumption, Pain After Surgery
Interventions: Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive; Drug
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
Interventions: Morphine, Epinephrine, naropin; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: POSTOPERATIVE PAIN
Interventions: Surgical TAP block, Conventional TAP block, 0.5% ropivacaine; Procedure · Drug
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Acute Pain
Interventions: Suzetrigine; Drug
Lead sponsor: Vertex Pharmaceuticals Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 5
States / cities: Atlanta, Georgia • Boston, Massachusetts • Bellaire, Texas + 2 more

Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
Interventions: Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 13,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 24
States / cities: Little Rock, Arkansas • San Francisco, California • Stanford, California + 18 more

Conditions: Postoperative Pain, Paracervical Block, Laparoscopic Gynecologic Surgery
Interventions: Bupivacaine, Normal Saline; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Female only
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Patient Preference
Interventions: Dexamethasone, Standard of care surgery; Drug · Other
Lead sponsor: Ophthalmic Consultants of Long Island; Other
Eligibility: 22 Years to 100 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Garden City, New York

Conditions: Pain
Interventions: placebo, valdecoxib; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 488 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 68
States / cities: Birmingham, Alabama • Northport, Alabama • Glendale, Arizona + 46 more

Conditions: Complications; Cesarean Section, Pregnancy
Interventions: Mobius Retractor; Device
Lead sponsor: Abbey Hardy-Fairbanks; Other
Eligibility: 18 Years and older · Female only
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Postoperative Pain
Interventions: EXPAREL and Local Anesthetics, Oral Opioid and Local Anesthetics; Procedure
Lead sponsor: Bellaire Facial Surgery Center; Other
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 3
States / cities: Atlanta, Georgia • Houston, Texas • The Woodlands, Texas

Conditions: Acute Pain, Surgery
Interventions: NeuroIDgenetix Test Panel; Other
Lead sponsor: AltheaDx; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Obesity
Interventions: 4% Lidocaine, Saline; Drug · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Thoracic Surgery
Interventions: Sham serratus anterior plane block, Serratus anterior plane block; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 6
States / cities: Middletown, New Jersey • Montvale, New Jersey • Commack, New York + 3 more

Conditions: Cryotherapy Effect, Compression, Postoperative Pain Management
Interventions: Game Ready Cryotherapy with Compression Group, Control Cryotherapy Group; Device · Other
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 348 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
Interventions: The Therapeutic Comfort Tote, The Modified Comfort Tote; Other
Lead sponsor: Columbia University; Other
Eligibility: 12 Years to 21 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Operative Pain
Interventions: Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel), ambIT Infusion Pump; Drug · Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Somerset, New Jersey

Conditions: Pain, Post-operative
Interventions: N1539, Intravenous Placebo; Drug
Lead sponsor: Baudax Bio; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 219 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 4
States / cities: Pasadena, California • Bellaire, Texas • San Antonio, Texas

Conditions: Bariatric Surgery, Cardiac Surgery With Sternotomy, Post-operative Pain
Interventions: Suzetrigine, Placebo; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 85 Years
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-Operative Pain, Lumbar Laminectomy
Interventions: Bupivacaine HCI without epinephrine, HTX-011, Luer Lock Applicator; Drug · Device
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 12
States / cities: Phoenix, Arizona • Pasadena, California • Wichita, Kansas + 9 more

Conditions: Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
Interventions: Temporo-masseteric Nerve Block Injection, Oral Pain Medications only; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
Interventions: Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment; Other
Lead sponsor: KK Women's and Children's Hospital; Government
Eligibility: 21 Years to 80 Years · Female only
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Postoperative Pain
Interventions: cyclobenzaprine; Drug
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Evanston, Illinois

Search by objective public record fields.

Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery

IV Ketorolac on Platelet Function Post-Cesarean Delivery

Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks

Peri-Incisional Drug Injection in Lumbar Spine Surgery

Comparative Study of Two Different Techniques to Perform TAP-blocks

A Single-Arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Aesthetic or Reconstructive Surgeries

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Effect of Paracervical Block on Post Operative Pain in Laparoscopic Gynecologic Surgery

A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery

Double-Blind, Randomized Study Of The Analgesic Efficacy And Safety Of Valdecoxib 20 Mg Daily And Valdecoxib 20 Mg Twice Daily Compared To Placebo For Management Of Acute Postsurgical Pain In Anterior Cruciate Ligament (ACL) Reconstruction

Mobius® Post-cesarean Pain Randomized Control Trial

Efficacy of EXPAREL in Comparison to Standard of Care for the Treatment of Post Operative Dental Implant Pain

Prospective Observational Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Patients Undergoing Elective Surgical Procedures

Sphenopalatine Ganglion Block to Prevent Shoulder Pain After Laparoscopic Bariatric Surgery

Ultrasound-Guided Serratus Anterior Plane Block for Additional Pain Relief After Lung Surgery

Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery

The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery

Post Operative Infusion Pump Pain Study

Evaluation of N1539 Following Abdominoplasty Surgery

Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery

HTX-011 in Spinal Surgery

Jaw Muscle Pain Post Wisdom Molar Surgery

Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery

Use of Cyclobenzaprine After Vaginal Surgery