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ClinicalTrials.gov public records Last synced Oct 29, 2026, 1:36 PM EDT

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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Reduction in Hospitalizations Clear all
Completed Phase 3 Interventional

The Congestive Heart Failure Adherence Redesign Trial

NCT01698242
View directory record Official record
Conditions
Heart Failure, Congestive, Cardiovascular Diseases, Heart Diseases
Interventions
Enhanced Training, Enhanced Education
Behavioral
Lead sponsor
Lynda Powell, PhD, MEd
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 29, 2026, 1:36 PM EDT
Terminated Phase 2 Interventional

Single Dose Enteral Tranexamic Acid in Critically Ill Patients

NCT01683747
View directory record Official record
Conditions
Shock, Sepsis, Hypotension, Critical Illness
Interventions
Tranexamic Acid, Control Intervention (Carrier fluid only)
Drug
Lead sponsor
San Diego Veterans Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2015 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Impact of a Data-driven Monitor Alarm Reduction Strategy Implemented in Safety Huddles

NCT02458872
View directory record Official record
Conditions
Hospitalization
Interventions
safety huddle alarm intervention
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
77,280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional

The Role of Therapy Dogs in Reducing Depression, Anxiety, and Loneliness Among Hospitalized Children

NCT05551156
View directory record Official record
Conditions
Hospitalized Children
Interventions
Animal-assisted interaction, Conversational interaction
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
8 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Phase 3 Interventional

Case Management and Environmental Control in Asthma

NCT00514436
View directory record Official record
Conditions
Asthma
Interventions
Asthma coaching
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 8 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2015 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Reducing Veterans Hospitalizations From Community Living Centers

NCT04195880
View directory record Official record
Conditions
Quality Improvement
Interventions
Interventions to Reduce Acute Care Transfers
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
6,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Animal-Assisted Therapy for Hospitalized Heart Failure Patients

NCT00391456
View directory record Official record
Conditions
Heart Failure
Interventions
Animal-assisted Therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2016 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program

NCT04281849
View directory record Official record
Conditions
Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure, Systolic, Heart Failure, Diastolic, Heart Failure，Congestive, Heart Failure; With Decompensation, Heart Failure Acute, Heart Failure With Reduced Ejection Fraction
Interventions
BAMS-HF Program
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
55 Years to 100 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 29, 2026, 1:36 PM EDT
Terminated Not applicable Interventional Results available

Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder

NCT03538444
View directory record Official record
Conditions
Opiate Dependence, Chronic Pain
Interventions
Repetitive Transcranial Magnetic Stimulation, Sham rTMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Results available

Reducing Emergency Diabetes Care for Older African Americans

NCT03466866
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
PREVENT, EUC (Enhanced Usual Care)
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
40 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Results available

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI

NCT02924727
View directory record Official record
Conditions
Acute Myocardial Infarction
Interventions
LCZ696 (sacubitril/valsartan), Ramipril, Placebo of LCZ696, Placebo of ramipril, Valsartan, Placebo of valsartan
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
5,669 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
81
States / cities
Birmingham, Alabama • Huntsville, Alabama • Gilbert, Arizona + 74 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 29, 2026, 1:36 PM EDT
Terminated Phase 3 Interventional Results available

Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)

NCT04745351
View directory record Official record
Conditions
COVID-19
Interventions
Remdesivir, RDV Placebo, Standard of Care
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
12 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
41
States / cities
Birmingham, Alabama • Mobile, Alabama • Eureka, California + 33 more
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Results available

RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial

NCT00358215
View directory record Official record
Conditions
Heart Failure, Anemia, Cardiovascular Disease, Ventricular Dysfunction, Congestive Heart Failure
Interventions
Darbepoetin alfa, Placebo
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
2,278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
254
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 195 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Using Clinical Alerts to Decrease Inappropriate Medication Prescribing

NCT01034761
View directory record Official record
Conditions
Elderly
Interventions
Pop-up alert
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
65 Years and older
Enrollment
719 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2015 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Results available

Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure

NCT00894387
View directory record Official record
Conditions
Acute Decompensated Heart Failure, Congestive Heart Failure
Interventions
Aliskiren, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
1,639 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
37
States / cities
Mobile, Alabama • Tucson, Arizona • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2013 · Synced Oct 29, 2026, 1:36 PM EDT
Terminated Phase 2 Interventional Results available

Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

NCT04722666
View directory record Official record
Conditions
Major Depressive Disorder With Suicidal Ideation With Intent
Interventions
MIJ821 Intravenous Injection, Placebo Intravenous Injection
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
6
States / cities
Birmingham, Alabama • Farmington, Connecticut • Oakland Park, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure

NCT00853658
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
Enalapril, Aliskiren
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
7,064 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
58
States / cities
Huntsville, Alabama • Mobile, Alabama • Tucson, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2016 · Synced Oct 29, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional

Massage Impact on Sleep in Pediatric Oncology

NCT06892158
View directory record Official record
Conditions
Cancer, Pediatric Cancer, Chemotherapy Effect, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Pediatric, Hematopoietic Stem Cell Transplantation (HSCT)
Interventions
Massage therapy, Standard of care
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 21 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 29, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional

Animal Assisted Therapy

NCT07227181
View directory record Official record
Conditions
Anxiety, Trauma, Hospitalized Adult Patients, Rehabilitation, Physical Mobility Impairment, Therapy Dog, Pediatric Patient (1m-21y)
Interventions
Therapy Dog, Standard mobilization
Other
Lead sponsor
Andrew Bernard
Other
Eligibility
4 Years to 99 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 29, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Reducing PTSD in Hospitalized Burn Patients

NCT02026037
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Brief Treatment for Acutely Burned Patients (BTBP)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2017 · Synced Oct 29, 2026, 1:36 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Heart Rate Variability Biofeedback With In-patient Pregnant Women

NCT02119936
View directory record Official record
Conditions
Maternal Stress, Maternal Anxiety, Maternal Health Services
Interventions
Heart Rate Variability Biofeedback Tool
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Oct 29, 2026, 1:36 PM EDT
Terminated Phase 3 Interventional Results available

This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure

NCT01035255
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
LCZ696 200 mg BID, Enalapril 10 mg BID
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
8,442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
155
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 129 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Oct 29, 2026, 1:36 PM EDT
Enrolling by invitation Phase 4 Interventional

Trial of Reducing Inpatient Antibiotic Durations in Children

NCT07322146
View directory record Official record
Conditions
Pneumonia, Skin and Soft Tissue (SST) Infection, Urinary Tract Infections (UTIs)
Interventions
Study Drug Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Days to 17 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
10
States / cities
Birmingham, Alabama • Aurora, Colorado • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 29, 2026, 1:36 PM EDT
Recruiting No phase listed Observational

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

NCT07209098
View directory record Official record
Conditions
Heart Failure and Reduced Ejection Fraction, NYHA Class III Heart Failure
Interventions
Cardiac Contractility Modulation (CCM)
Device
Lead sponsor
Impulse Dynamics
Industry
Eligibility
18 Years and older
Enrollment
4,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Marlton, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 29, 2026, 1:36 PM EDT