- Conditions
- Embolic Stroke of Undetermined Source, Transient Ischemic Attack, Right-To-Left Atrial Shunt, Patent Foramen Ovale
- Interventions
- NeuralBot Investigational System, Transthoracic Echocardiography (TTE)
- Diagnostic Test
- Lead sponsor
- NeuraSignal Inc dba NovaSignal
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 7
- States / cities
- Phoenix, Arizona • Portland, Oregon • Chattanooga, Tennessee + 3 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 50
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Foramen Ovale, Patent
- Interventions
- Aspirin, Cardiovascular Implantable Device (CIED), Gore Cardioform Septal Occluder
- Drug · Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke
- Interventions
- Encore PFO closure device, FDA-approved PFO closure device
- Device
- Lead sponsor
- Encore Medical Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2030
- U.S. locations
- 8
- States / cities
- Little Rock, Arkansas • La Jolla, California • Tampa, Florida + 5 more
- Conditions
- Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale, PIVSD - Post Infarct Muscular Ventricular Septal Defect, Valvular Heart Disease
- Interventions
- Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- Not listed
- Enrollment
- 2,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2039
- U.S. locations
- 13
- States / cities
- Los Angeles, California • Washington D.C., District of Columbia • Miami, Florida + 9 more
- Conditions
- Migraine Headaches, Patent Foramen Ovale
- Interventions
- Sham Procedure, AMPLATZER PFO Occluder
- Other · Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 230 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2015
- U.S. locations
- 30
- States / cities
- Phoenix, Arizona • Los Angeles, California • Colorado Springs, Colorado + 23 more
- Conditions
- Stroke, Patent Foramen Ovale
- Interventions
- AMPLATZER™ PFO Occluder
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 1,214 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 78
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Chandler, Arizona + 63 more
- Conditions
- Migraine Disease, Patent Foramen Ovale
- Interventions
- Prasugrel 5mg, Transcatheter Closure of Patent Foramen Ovale
- Drug · Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cryptogenic Stroke
- Interventions
- AMPLATZER PFO Occluder, Standard of Care - Medical Management
- Device · Other
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 980 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2016
- U.S. locations
- 61
- States / cities
- Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 52 more
- Conditions
- Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
- Interventions
- Flow Detection System
- Device
- Lead sponsor
- Cardiox Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 141 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more
- Conditions
- Septal Defect, Atrial
- Interventions
- GORE® HELEX® Septal Occluder
- Device
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- Not listed
- Enrollment
- 215 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2014
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Migraine, Patent Foramen Ovale, PFO - Patent Foramen Ovale
- Interventions
- Actual device PFO closure, Thienopyridine (clopidogrel or prasugrel), Sham device PFO closure
- Device · Drug
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 15
- States / cities
- Phoenix, Arizona • Los Angeles, California • Santa Barbara, California + 11 more
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke, Embolic Infarction
- Interventions
- intravenous access in greater saphenous vein compared to upper extremity site.
- Diagnostic Test
- Lead sponsor
- St. John's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Maple Grove, Minnesota
- Conditions
- Patent Foramen Ovale
- Interventions
- PFO Closure
- Other
- Lead sponsor
- University of Oregon
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Patent Foramen Ovale (PFO)
- Interventions
- Point-of-care ultrasound
- Diagnostic Test
- Lead sponsor
- Scripps Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Patent Foramen Ovale
- Interventions
- Not listed
- Lead sponsor
- University of Oregon
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 28 participants
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Septal Defect, Atrial
- Interventions
- GORE® CARDIOFORM Septal Occluder
- Device
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- Not listed
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Ischemic Brain Injury, Stroke, Healthy Individual, Patent Foramen Ovale (PFO), Neurovascular Injury
- Interventions
- Not listed
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- Not listed
- Enrollment
- 750 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Stroke, Patent Foramen Ovale, PFO
- Interventions
- Investigational PFO Closure Device, Standard of Care PFO Closure Device
- Device
- Lead sponsor
- Occlutech International AB
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2029
- U.S. locations
- 27
- States / cities
- Phoenix, Arizona • Stanford, California • Thousand Oaks, California + 20 more
- Conditions
- Septal Defect, Atrial
- Interventions
- atrial septal defect closure
- Device
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Heart Septal Defect, Heart Septal Defects, Atrial, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases, Congenital Abnormalities
- Interventions
- reSept ASD Occluder
- Device
- Lead sponsor
- atHeart Medical
- Industry
- Eligibility
- Up to 84 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2032
- U.S. locations
- 24
- States / cities
- Birmingham, Alabama • Los Angeles, California • Thousand Oaks, California + 21 more
- Conditions
- Atrial Septal Defect Secundum
- Interventions
- atrial septal occluder
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- Not listed
- Enrollment
- 602 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 65
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 50 more
- Conditions
- Stroke, PFO - Patent Foramen Ovale
- Interventions
- PFO closure with GORE® CARDIOFORM Septal Occluder
- Device
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 636 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2031
- U.S. locations
- 45
- States / cities
- Tucson, Arizona • La Jolla, California • Loma Linda, California + 39 more
- Conditions
- Ischemic Stroke, Patent Foramen Ovale
- Interventions
- Warfarin, Aspirin
- Drug
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 630 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1993 – 2000
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Atrial Septal Defect, Patent Foramen Ovale, Allergic Reaction to Nickel
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah