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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:13 AM EDT

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Showing 49–72 of 187 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sinusitis Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery

NCT02687438
View directory record Official record
Conditions
Chronic Sinusitis
Interventions
Steroid-releasing sinus implant, Post-op standard of care
Device · Other
Lead sponsor
ENT and Allergy Associates, LLP
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Lake Success, New York • New York, New York • Port Jefferson, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis

NCT03705793
View directory record Official record
Conditions
Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis
Interventions
Mometasone Furoate Nasal Irrigation, Mometasone Nasal Spray
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 20, 2026, 10:13 AM EDT
Completed No phase listed Observational Results available

Comparative Effectiveness of Antibiotics for Respiratory Infections

NCT02297815
View directory record Official record
Conditions
Acute Otitis Media, Acute Sinusitis, Group A Streptococcal Pharyngitis
Interventions
Broad-spectrum antibiotics, Narrow-spectrum antibiotics
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Months to 12 Years
Enrollment
2,472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Oct 20, 2026, 10:13 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Maxillary Sinus Membrane Perforation Incidence During Osseodensification

NCT05954273
View directory record Official record
Conditions
Sinus Floor Augmentation, Sinus Infection
Interventions
Osseodensification crestal sinsus graft
Procedure
Lead sponsor
Versah
Industry
Eligibility
21 Years to 90 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Jackson, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 2 Interventional

A Study To Measure The Level Of Drug In Nasal Tissue And Blood After Taking A Single 2g Dose Or 500mg Tablets For Up To

NCT00232154
View directory record Official record
Conditions
Sinusitis
Interventions
Zithromax™ (azithromycin) 500mg tablets, Endoscopic Sinus Surgery, Blood sampling for hematology, Blood sampling for plasma chemistry profile, Serum pregnancy test (for women of child-bearing potential)
Drug · Procedure
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
18
States / cities
Alabaster, Alabama • Birmingham, Alabama • Hoover, Alabama + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2011 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 4 Interventional Results available

Erenumab for Idiosyncratic Facial Pain

NCT04249427
View directory record Official record
Conditions
Facial Pain, Rhinosinusitis
Interventions
Erenumab Prefilled Syringe, Placebo
Drug · Other
Lead sponsor
David Jang, M.D.
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Vitamin D for Chronic Sinusitis

NCT01007799
View directory record Official record
Conditions
Chronic Sinusitis
Interventions
vitamin D placebo, Vitamin D
Dietary Supplement
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2016 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 3 Interventional

AMS VS MOXI Ketek vs Avelox in AMS

NCT00537563
View directory record Official record
Conditions
Maxillary Sinusitis
Interventions
Telithromycin
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study

NCT00871286
View directory record Official record
Conditions
Chronic Rhinosinusitis
Interventions
Pre-treatment Sinus CT Scan, Post-treatment Sinus CT Scan
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 18, 2012 · Synced Oct 20, 2026, 10:13 AM EDT
Terminated Not applicable Interventional Results available

Trial of Verapamil in Chronic Rhinosinusitis

NCT02454608
View directory record Official record
Conditions
Sinusitis, Nasal Polyps
Interventions
Verapamil HCl, Placebo
Drug · Other
Lead sponsor
Benjamin Bleier
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Oct 20, 2026, 10:13 AM EDT
Terminated Phase 4 Interventional

Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis

NCT00245440
View directory record Official record
Conditions
Maxillary Sinusitis
Interventions
Azithromycin, Telithromycin
Drug
Lead sponsor
CPL Associates
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Taylors, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2007 · Synced Oct 20, 2026, 10:13 AM EDT
Withdrawn Early Phase 1 Interventional

Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis

NCT03729310
View directory record Official record
Conditions
Chronic Sinusitis, Rhinosinusitis
Interventions
Propel 'implant', Triamcinolone, Nasopore
Device · Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Oct 20, 2026, 10:13 AM EDT
Not listed No phase listed Observational

Impact of Triple Combination CFTR Therapy on Sinus Disease.

NCT04056702
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Elexacaftor-tezacaftor-ivacaftor exposure
Drug
Lead sponsor
Jennifer Taylor-Cousar
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 3 Interventional

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

NCT00644553
View directory record Official record
Conditions
Acute Bacterial Sinusitis (ABS)
Interventions
Clarithromycin, Amoxicillin
Drug
Lead sponsor
Abbott
Industry
Eligibility
12 Years and older
Enrollment
437 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
12
States / cities
Birmingham, Alabama • Phoenix, Arizona • Clovis, California + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2008 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 1Phase 2 Interventional

SynRinse Irrigation Pilot (SIP) Trial

NCT03154541
View directory record Official record
Conditions
Sinusitis, Chronic, Cystic Fibrosis With Other Manifestations
Interventions
Synrinse
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 3 Interventional Results available

BAY12-8039: 5 Days for Sinusitis vs Placebo

NCT00492024
View directory record Official record
Conditions
Sinusitis
Interventions
Moxifloxacin (Avelox, BAY12-8039), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
51
States / cities
Birmingham, Alabama • Northport, Alabama • Jonesboro, Arkansas + 45 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2013 · Synced Oct 20, 2026, 10:13 AM EDT
Completed No phase listed Observational

Sinusitis in Children and the Nasopharyngeal Microbiome

NCT01492868
View directory record Official record
Conditions
Sinusitis
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
4 Years to 7 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 8, 2018 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Acupuncture and Herbal Treatment of Chronic HIV Sinusitis

NCT00002149
View directory record Official record
Conditions
HIV Infections, Sinusitis
Interventions
Clavulanate potassium, Pseudoephedrine hydrochloride, Amoxicillin trihydrate
Drug
Lead sponsor
Immune Enhancement Project
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 20, 2026, 10:13 AM EDT
Terminated Not applicable Interventional

Efficacy of Seprapack Sinus Dressing Versus No Dressing in the Prevention of Intranasal Adhesions Following Sinus Surgery

NCT00140608
View directory record Official record
Conditions
Chronic Sinusitis
Interventions
Seprapack Sinus Dressing
Device
Lead sponsor
Genzyme, a Sanofi Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
3
States / cities
Charleston, North Carolina • Cincinnati, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults

NCT05219968
View directory record Official record
Conditions
Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis)
Interventions
LYR-210, Sham procedure control, Background Therapy
Drug · Other
Lead sponsor
Lyra Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
26
States / cities
Birmingham, Alabama • Escondido, California • La Mesa, California + 21 more
Source: ClinicalTrials.gov public record
Updated May 2, 2025 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 2 Interventional Results available

Balloon REmodeling Antrostomy THErapy Study

NCT00645762
View directory record Official record
Conditions
Sinusitis
Interventions
RS-Series Rhinosinusitis Treatment System, FinESS Balloon
Device
Lead sponsor
Entellus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
13
States / cities
Fresno, California • Evanston, Illinois • Maywood, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2013 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 4 Interventional Results available

The PIO II Study: In-office Post-op Placement of a Steroid-eluting Sinus Implant

NCT02668302
View directory record Official record
Conditions
Chronic Sinusitis, Ethmoidal
Interventions
Steroid-eluting sinus implant, Post-op standard of care
Combination Product · Other
Lead sponsor
Collin County Ear Nose & Throat
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 2 Interventional Results available

LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study)

NCT05035654
View directory record Official record
Conditions
Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis)
Interventions
LYR-220 Design 1 (Part 1 only), LYR-220 Design 2 (Part 1 and Part 2), Bilateral sham procedure control (Part 2)
Drug
Lead sponsor
Lyra Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
22
States / cities
Carlsbad, California • La Mesa, California • Roseville, California + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 20, 2026, 10:13 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps

NCT01732536
View directory record Official record
Conditions
Chronic Sinusitis, Nasal Polyps
Interventions
S8 Sinus Implant, Sham procedure, Mometasone furoate nasal spray
Drug · Procedure
Lead sponsor
Intersect ENT
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
19
States / cities
Atherton, California • Los Angeles, California • Sacramento, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 20, 2026, 10:13 AM EDT