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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:57 AM EDT

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Showing 361–384 of 3,839 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Clear all
Completed Phase 4 Interventional Results available

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study

NCT04789174
View directory record Official record
Conditions
Excessive Daytime Sleepiness, Obstructive Sleep Apnea, Impaired Cognitive Function
Interventions
Solriamfetol, Placebo
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
15
States / cities
Los Angeles, California • Santa Ana, California • Jacksonville, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The EMS Sleep Health Study: A Randomized Controlled Trial

NCT04218279
View directory record Official record
Conditions
Sleep Quality, Fatigue
Interventions
Sleep Health Education
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
678 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Oct 20, 2026, 10:57 AM EDT
Terminated Phase 4 Interventional Results available

Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease

NCT01554488
View directory record Official record
Conditions
Asthma, Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Interventions
Inhaled Fluticasone Propionate
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 20, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional

Sleep Treatment for Teens (RCT Phase)

NCT07303959
View directory record Official record
Conditions
Sleep Problems, Suicidal Ideation, Suicidal Behavior
Interventions
Sleepio, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
14 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Piscataway, New Jersey • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Not listed Not applicable Interventional

The Effect of Magnesium Citrate Supplementation in Restless Legs Syndrome (RLS)

NCT04462796
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
Magnesium Citrate
Dietary Supplement
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2023 · Synced Oct 20, 2026, 10:57 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

NCT04723862
View directory record Official record
Conditions
Hyperandrogenism, Polycystic Ovary Syndrome, Puberty
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
10 Years to 17 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 20, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional

Sleep Mechanisms Of Regulating Emotions

NCT06373718
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional

The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes

NCT03713996
View directory record Official record
Conditions
Type2 Diabetes, Insomnia
Interventions
Cognitive behavioral therapy for insomnia, Health Education
Behavioral · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 20, 2026, 10:57 AM EDT
Terminated Phase 2 Interventional Results available

Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer Patients

NCT01921296
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Pain
Interventions
Cyclobenzaprine
Drug
Lead sponsor
Lynn Henry
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Dual Treatment of Chronic Pain and Insomnia

NCT05033418
View directory record Official record
Conditions
Insomnia, Chronic Pain
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Interdisciplinary Pain Rehabilitation Program (IPRP)
Behavioral
Lead sponsor
Mary Free Bed Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 2, 2021 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Acupuncture for Sleep Disruption in Cancer Survivors

NCT01162018
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Breast Cancer
Interventions
acupuncture, placebo
Procedure · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep and Social Experiences Study 2

NCT05166590
View directory record Official record
Conditions
Sleep, Blood Pressure
Interventions
Sleep Restriction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 64 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Sleep and Healthy Aging Research on Depression for Younger Women

NCT03848715
View directory record Official record
Conditions
Anhedonia, Depression
Interventions
Endotoxin, Placebo
Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
25 Years to 44 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Yoga During Chemotherapy Study

NCT02442635
View directory record Official record
Conditions
Cancer, Sleep Disturbance, Fatigue
Interventions
Yoga
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2019 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional

A Computerized CBTi for Insomnia in Epilepsy

NCT03632889
View directory record Official record
Conditions
Epilepsy, Insomnia
Interventions
GoToSleep Program
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 20, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Location- and Frequency-Dependent Effects of Thalamic Temporal Interference Stimulation During Sleep

NCT07498270
View directory record Official record
Conditions
Healthy Adult Participants, Healthy Participants
Interventions
Magnetic Resonance Imaging (MRI), Broad thalamic stimulation (TI-TES), Carrier only SHAM stimulation, Anterior thalamic stimulation (TI-TES), Posterior thalamic stimulation (TI-TES)
Other · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Countermeasures to Circadian Misalignment

NCT04966351
View directory record Official record
Conditions
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity
Interventions
Time-restricted feeding, Circadian Misalignment
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep, Diet, Exercise and Older Persons

NCT05735353
View directory record Official record
Conditions
Cognitive Change, Cognitive Decline
Interventions
High-Speed Circuit Resistance Training, High-Speed Multidirectional Yoga
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
60 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Somato® (Phytomelatonin) Versus Synthetic Melatonin and Placebo on Sleep Quality

NCT07669766
View directory record Official record
Conditions
Sleep
Interventions
Plant-based melatonin, Melatonin, Placebo
Dietary Supplement
Lead sponsor
Nutraland USA, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
244 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional Results available

Understanding Trauma Nightmares Using In-Home Measurement

NCT03974503
View directory record Official record
Conditions
Nightmares, Stress Disorders, Post-Traumatic, Actigraphy, Respiratory Sinus Arrhythmia, Veterans
Interventions
Exposure, Relaxation, and Rescripting Therapy, Sleep and Nightmare Management
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional Results available

Combination Therapy to Treat Sleep Apnea

NCT01633827
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Placebo pill, Sedative, Room air, Oxygen
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Phase 3 Interventional

National Adaptive Trial for PTSD Related Insomnia

NCT03668041
View directory record Official record
Conditions
Insomnia
Interventions
Trazodone, Eszopiclone, Placebo
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
673 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
35
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 31 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 20, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep, Exercise, Nutrition and Survivorship in Prostate Cancer

NCT05318131
View directory record Official record
Conditions
Prostate Cancer
Interventions
Sleep and Lifestyle Advice Website, Surveys and Sleep Monitors
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 20, 2026, 10:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep Apnea

NCT02721251
View directory record Official record
Conditions
Obstructive Sleep Apnea, Overweight
Interventions
Exercise, Weight Loss, Exercise + Weight Loss
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Oct 20, 2026, 10:57 AM EDT