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ClinicalTrials.gov public records Last synced Oct 26, 2026, 1:27 PM EDT

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Showing 1177–1200 of 2,614 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbance Clear all
Active, not recruiting No phase listed Observational

A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities

NCT01857427
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years to 70 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional

Targeted Hypoglossal Neurostimulation Study #3

NCT02263859
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
aura6000 System
Device
Lead sponsor
ImThera Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
14
States / cities
Chula Vista, California • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 26, 2026, 1:27 PM EDT
Recruiting Not applicable Interventional

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

NCT07216261
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Implementation Strategy: Foundational Arm, Implementation Strategy: REACH arm
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Phase 3 Interventional Results available

PMP-300E (Smart Watch): Portable Monitoring Device Study

NCT01364740
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
PMP-300E, In-lab PSG
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Redwood City, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Oct 26, 2026, 1:27 PM EDT
Active, not recruiting Not applicable Interventional

Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea

NCT03109210
View directory record Official record
Conditions
Insomnia, Primary, Sleep Apnea, Obstructive
Interventions
Online Cognitive Behavioral Therapy (OCBT), Therapist-directed Cognitive Behavioral Therapy (TCBT)
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
21 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

Clinical Study for the BONGO Device in the Treatment of Obstructive Sleep Apnea (OSA)

NCT02878590
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
BONGO DEVICE
Device
Lead sponsor
InnoMed Healthscience Inc.
Industry
Eligibility
21 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients

NCT03148262
View directory record Official record
Conditions
Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea, High Flow Nasal Cannula
Interventions
The Comfort Flo system, The Salter nasal cannula
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Oct 26, 2026, 1:27 PM EDT
Recruiting Phase 1Phase 2 Interventional

Low-Tech Treatments for Obstructive Sleep Apnea

NCT07301710
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Traumatic Brain Injury (TBI)
Interventions
High-Resistance Breathing and Drinking Exercises, Low-Resistance Breathing and Drinking Exercises
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness Research to Enhance Outcomes in African-Americans With Obstructive Sleep Apnea

NCT01997723
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Portable monitoring, Polysomnography, Home portable monitoring, Laboratory portable monitoring
Device · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 26, 2026, 1:27 PM EDT
Recruiting Not applicable Interventional

The Recovery in Stroke Using PAP Study

NCT04130503
View directory record Official record
Conditions
Ischemic Stroke, Obstructive Sleep Apnea
Interventions
PAP, HLE
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder

NCT03375203
View directory record Official record
Conditions
Insomnia Disorders
Interventions
Placebo, JNJ-42847922, 5 mg, JNJ-42847922, 10 mg, JNJ-42847922, 20 mg, Zolpidem
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
24
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Anaheim, California + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?

NCT01184118
View directory record Official record
Conditions
Lung Disease
Interventions
FP 220 mcg 2 puffs BID
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

The Evaluation of the Toffee Mask for the Treatment of Obstructive Sleep Apnea

NCT03726346
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Toffee Full Face Mask
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 26, 2026, 1:27 PM EDT
Not listed Phase 2 Interventional

Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea

NCT02069197
View directory record Official record
Conditions
Obesity, Diabetes, Obstructive Sleep Apnea
Interventions
Ketogenic diet, Orlistat, Standardized diet
Other · Drug
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 26, 2026, 1:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep and Metabolism

NCT05775627
View directory record Official record
Conditions
Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain, Food Selection
Interventions
Sleep Restriction
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia

NCT00928720
View directory record Official record
Conditions
Fibromyalgia
Interventions
CES device, sham device
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 26, 2026, 1:27 PM EDT
Withdrawn Phase 1Phase 2 Interventional

The Effect of Obstructive Sleep Apnea on Medical Outcomes After Gastric Bypass Surgery

NCT00671983
View directory record Official record
Conditions
Obesity, Sleep Apnea, Obstructive
Interventions
Neurocognitive Testing
Procedure
Lead sponsor
Stanford University
Other
Eligibility
30 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Phase 2 Interventional

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

NCT05951023
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Eszopiclone 2 mg, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder

NCT03668873
View directory record Official record
Conditions
Autism Spectrum Disorder, Sleep Disturbance
Interventions
Sleep Parent Training, Sleep Parent Education
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
2 Years to 7 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 26, 2026, 1:27 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Obstructive Sleep Apnea and Glucose Metabolism

NCT03408613
View directory record Official record
Conditions
Sleep Apnea, Glucose Metabolism Disorders
Interventions
Positive Airway Pressure, Supplemental Oxygen, Sham
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
30 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Phase 3 Interventional

A 28-Day Polysomnographic Study of Gabapentin in Transient Insomnia Induced by a Sleep Phase Advance

NCT00163046
View directory record Official record
Conditions
Transient Insomnia
Interventions
Gabapentin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
3
States / cities
Glendale, California • San Diego, California • Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep, Aging and Risk for Alzheimer's Disease

NCT01962779
View directory record Official record
Conditions
Sleep Disordered Breathing, Alzheimer's Disease
Interventions
Continuous positive airway pressure (CPAP)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 26, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

Hypoglossal Nerve Stimulation on Cardiovascular Outcomes

NCT03359096
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Therapeutic HGNS, Subtherapeutic 'Sham' HGNS
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 26, 2026, 1:27 PM EDT
Withdrawn Not applicable Interventional

Comparison of Modafinil and Methylphenidate in Treatment of Excessive Daytime Sleepiness in Patients With Parkinson's Disease

NCT00393562
View directory record Official record
Conditions
Parkinson's Disease
Interventions
modafinil, methylphenidate
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 26, 2015 · Synced Oct 26, 2026, 1:27 PM EDT