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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 3 Interventional Results available

VEC-162 Study in Adult Patients With Primary Insomnia

NCT00548340
Conditions
Primary Insomnia
Interventions
VEC-162 20 mg, Placebo, VEC-162 50 mg
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years to 64 Years
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
35
States / cities
Birmingham, Alabama • Hot Springs, Arkansas • Little Rock, Arkansas + 32 more
Conditions
Bipolar Disorder, Sleep Problems, Suicidal Thoughts
Interventions
Brief Sleep Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Rakesh Sondekoppam Vijayashankar
Other
Eligibility
18 Years to 85 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 2 Interventional Results available

Trial of AD036 in Obstructive Sleep Apnea

NCT03845023
Conditions
Obstructive Sleep Apnea
Interventions
AD036 Dose 1, AD036 Dose 2, AD036 Dose 3, Placebo
Drug
Lead sponsor
Apnimed
Industry
Eligibility
25 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
12
States / cities
Glendale, Arizona • Little Rock, Arkansas • Redwood City, California + 9 more
Conditions
Obstructive Sleep Apnea, Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
45 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2014
U.S. locations
4
States / cities
New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania + 1 more
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Southeast Louisiana Veterans Health Care System
Federal
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea

NCT04121923
Conditions
Sleep Apnea, Obstructive
Interventions
Belun Ring Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers

NCT00001546
Conditions
Sleep Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Obstructive Sleep Apnea
Interventions
Trans Nasal Insufflation (TNI) [nasal canula]
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Results available

The Effect of Horizant (Gabapentin Enacarbil) on Augmentation

NCT02642315
Conditions
Restless Legs Syndrome
Interventions
Horizant
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Obstructive Sleep Apnea, Spinal Cord Injuries
Interventions
Mild intermittent hypoxia, Sham protocol, Continuous positive airway pressure (CPAP)
Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Detroit, Michigan
Conditions
Insomnia
Interventions
JNJ-42847922, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Hollywood, Florida
Conditions
Anxiety, Cancer Survivor, Chronic Pain, Depression, Sleep Disorder
Interventions
Hypnotherapy, Questionnaire Administration
Procedure · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Insomnia, Insomnia Chronic
Interventions
Zolpidem tartrate
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 85 Years
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Not applicable Interventional

Assessing Modified CBTi in Adults With Insomnia Disorder

NCT06600516
Conditions
Insomnia Disorder, Cognitive Functioning
Interventions
CBTi: Stimulus Control Core, CBTi: Sleep Restriction Core, CBTi: Sleep Compression Core
Behavioral
Lead sponsor
Idaho State University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pocatello, Idaho
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease

NCT02162862
Conditions
Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
Interventions
Behavioral Counseling, bupropion-SR
Behavioral · Drug
Lead sponsor
Eva Szigethy
Other
Eligibility
15 Years to 30 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Conditions
Sleep Deprivation, Insomnia, Metabolic Syndrome
Interventions
sleep chatbot
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 25 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Hemoglobinuria, Paroxysmal
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
7 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Chronic Pain, Sleep Disturbance
Interventions
Weighted blanket
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
San Diego, California • San Francisco, California
Completed Phase 1Phase 2 Interventional Results available

Flumazenil for the Treatment of Primary Hypersomnia

NCT01183312
Conditions
Hypersomnia, Primary Hypersomnia, Idiopathic Hypersomnia, Narcolepsy Without Cataplexy
Interventions
Flumazenil
Drug
Lead sponsor
Lynn Marie Trotti
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Orthopedic Trauma, Sleep Quality
Interventions
Standard Postoperative Care, Zolpidem, Melatonin, Sleep Hygiene Education, Actigraph GT3X-BT Actigraph
Other · Drug · Dietary Supplement + 2 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

NCT06345872
Conditions
Chronic Pain, Chronic Insomnia, Opioid Use
Interventions
CBT-I, Treatment as usual, Tapered Withdrawal
Behavioral · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Terminated Not applicable Interventional Accepts healthy volunteers

Sleep Disruption in Post-operative Patients in the Neurocritical Care Unit

NCT02997839
Conditions
Sleep Fragmentation
Interventions
sleep disruption
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland