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ClinicalTrials.gov public records Last synced Nov 11, 2026, 8:13 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 2,612 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Insomnia
Interventions: Go! to Sleep; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 89 Years
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Atrial Fibrillation, Obstructive Sleep Apnea
Interventions: Delayed enhancement magnetic resonance imaging (DE-MRI); Device
Lead sponsor: Tulane University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 3
States / cities: New Orleans, Louisiana

Conditions: Sleep Disturbance
Interventions: Placebo Rest Control, Active Rest Product 1; Dietary Supplement
Lead sponsor: Radicle Science; Industry
Eligibility: 21 Years to 105 Years
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Del Mar, California

Conditions: Insomnia Chronic
Interventions: lumbar puncture; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 30 Years to 50 Years
Enrollment: 30 participants
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obstructive Sleep Apnea
Interventions: Inspire Upper Airway Stimulation System; Device
Lead sponsor: Inspire Medical Systems, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 929 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 15
States / cities: Palo Alto, California • St. Petersburg, Florida • Tampa, Florida + 12 more

Conditions: REM Behavior Disorder, Parkinson Disease
Interventions: Not listed
Lead sponsor: CND Life Sciences; Other
Eligibility: 50 Years to 85 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 18
States / cities: Scottsdale, Arizona • Irvine, California • Los Angeles, California + 14 more

Conditions: Narcolepsy
Interventions: Not listed
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Parkinson's Disease, Poor Quality Sleep, Hypersomnia
Interventions: Structured Physical Activity, Sleep hygiene education; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 50 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Breast Cancer
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 50 Years and older · Female only
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Obstructive Sleep Apnea, Obesity
Interventions: Laparoscopic Gastric Banding, Continuous Positive Airway Pressure; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Sleep Problems, Insomnia
Interventions: Tart Cherry Juice, Placebo juice; Other
Lead sponsor: Courtney Millar; Other
Eligibility: 65 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Roslindale, Massachusetts

Conditions: Insomnia, Psychosis
Interventions: Cognitive Behavioral Therapy-Insomnia, Health and Wellness; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep Disorders, Circadian Rhythm
Interventions: Melatonin, Placebo; Dietary Supplement · Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Sleep Disorder, Restless Legs Syndrome, Opioid-use Disorder, Opioid Withdrawal
Interventions: Pramipexole, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Boston, Massachusetts • Quincy, Massachusetts

Conditions: Anxiety, Stress
Interventions: Alcohol Alternative Herbal Tincture (Test Product), Placebo; Dietary Supplement
Lead sponsor: Apothekary; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Restless Legs Syndrome
Interventions: Noctrix Health NPNS device v1.0 - Active, Noctrix Health NPNS device v1.0 - Sham; Device
Lead sponsor: Noctrix Health, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Downey, California • Menlo Park, California • San Ramon, California

Conditions: Obstructive Sleep Apnea
Interventions: blood biomarker; Diagnostic Test
Lead sponsor: Beckman Coulter, Inc.; Industry
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: Irvine, California • Boston, Massachusetts • Columbia, South Carolina

Conditions: Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
Interventions: ORX750; Drug
Lead sponsor: Centessa Pharmaceuticals (UK) Limited; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 19
States / cities: Auburn, Alabama • Santa Ana, California • Miami, Florida + 14 more

Conditions: Obstructive Sleep Apnea, Obesity
Interventions: Standard care with a facemask., SuperNO2VA™EtCO2 (Nasal Oxygenating Ventilating Apparatus); Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Obstructive Sleep Apnea
Interventions: Portable monitoring, Polysomnography, Home portable monitoring, Laboratory portable monitoring; Device · Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Insomnia
Interventions: Internet-based Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: VA Connecticut Healthcare System; Federal
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Restless Legs Syndrome, Insomnia, Sleep Disorder
Interventions: Suvorexant, Placebo; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 25 Years to 85 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia
Interventions: Computerized Plasticity-Based Adaptive Cognitive Training, Sleep Hygiene Education; Other
Lead sponsor: Posit Science Corporation; Industry
Eligibility: 65 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Autism Spectrum Disorders, Insomnia
Interventions: Telephone Care Management, Usual Care; Behavioral
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 3 Years to 6 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Columbus, Ohio

Search by objective public record fields.

Effectiveness and Adherence to an Online Sleep Program

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Radicle RestTM VGI: A Study Assessing the Impact of Health and Wellness Products on Sleep and Related Health Outcomes

Chronic Insomnia and CSF Markers of Dementia

Stimulation Therapy for Apnea Reduction (Www.theSTARtrial.Com)

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

Body Weight Regulation in Patients With Narcolepsy

Structured Physical Activity for Sleep Quality and Daytime Sleepiness in Patients With Parkinson's Disease

Examining the Relationships Between Sleep, Fatigue, and Pain in Aromatase Inhibitor-treated Patients

Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial

Tart Cherry Juice for Sleep in Older Adults With Insomnia: A Pilot Study of Feasibility and Comprehensive Mechanisms

CBT-I for Psychosis: Guidelines, Preliminary Efficacy, and Functional Outcomes

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

A Clinical Trial to Assess the Impact of an Alcohol Alternative Herbal Tincture on Signs of Stress Anxiety and Sleep Quality.

Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome

Use of Blood Biomarkers and Biomarker Index to Aid in the Diagnosis of Obstructive Sleep Apnea (OSA)

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Effect of Nasal Positive Airway Pressure Versus Standard Care on Oxygenation and Ventilation During Propofol-based Sedation for Colonoscopy in Patients With High Risk of Airway Obstruction

Comparative Effectiveness Research to Enhance Outcomes in African-Americans With Obstructive Sleep Apnea

Piloting an Internet-based Therapy for Insomnia in a Population of Veterans With Substance Use Disorders

Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia

Remote STATE Training for Insomnia in Older Adults

Telephone Care Management to Address Sleep Problems in Young Children With Autism