Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:05 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1393–1416 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Sleep, Sleep Deprivation, Insufficient Sleep Syndrome
Interventions: Sleep:wake 1, Sleep:wake 2; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 35 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Coronary Artery Disease, Sleep Disorder; Breathing-Related, Sleep Disorder; Insomnia Type
Interventions: Polysomnograpy, actigraphy; Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 99 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
Interventions: CBT-OSA, Sleep Education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder), Post-Infectious Arthritis, Post-Infectious Polyneuritis, Post-Infectious Parkinsonism, Post-Infectious Hypothyroidism, Post Infectious Osteoarthritis, Anxiety Disorders, Depression, Depression, Anxiety, Depression, Bipolar, Insomnia, GERD, Gastro Esophageal Reflux, Hepatitis, Glomerulonephritis
Interventions: PurWet, FurFat, PurApo, PurPhl, PurClo, PurInf, Smoliv; Combination Product
Lead sponsor: All Natural Medicine Clinic, LLC; Other
Eligibility: Not listed
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Rockville, Maryland

Conditions: Obstructive Sleep Apnea, Obesity
Interventions: CPAP followed by atmospheric pressure, Atmospheric pressure followed by CPAP; Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstructive Sleep Apnea
Interventions: RPMO2 OSA Device; Device
Lead sponsor: ProSomnus Sleep Technologies; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Insomnia, Post Partum Depression
Interventions: dCBTI, Sleep Education; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Cardiopulmonary Disease
Interventions: TEE with SGA, TEE with Deep Sedation; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 120 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Spinal Cord Injury
Interventions: Powerlung Performer; Device
Lead sponsor: Texas State University, San Marcos; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: San Marcos, Texas

Conditions: Obstructive Sleep Apnea
Interventions: CPAP, Auto BiLevel; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 3
States / cities: Boston, Massachusetts • Rochester, Minnesota • St Louis, Missouri

Conditions: Cancer, Insomnia
Interventions: Sleep Healthy Using the Internet (SHUTi), Hypnosis recordings; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 21 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Obstructive Sleep Apnea
Interventions: Auto AFlex, Auto CPAP, CPAP; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 4
States / cities: Birmingham, Alabama • Stanford, California • New Haven, Connecticut + 1 more

Conditions: Anxiety, Depression, Insomnia, Sleep Quality
Interventions: Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator); Device
Lead sponsor: Christina Murphey, RN, PhD; Individual
Eligibility: 18 Years to 45 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Austin, Texas • Corpus Christi, Texas

Conditions: Healthy, Narcolepsy
Interventions: MK-6552, Modafinil; Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Narcolepsy, Cataplexy, Excessive Daytime Sleepiness
Interventions: AXS-12 (reboxetine), Placebo; Drug
Lead sponsor: Axsome Therapeutics, Inc.; Industry
Eligibility: 15 Years to 75 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 24
States / cities: Phoenix, Arizona • Boulder, Colorado • Colorado Springs, Colorado + 20 more

Conditions: Obstructive Sleep Apnea
Interventions: IHL-42X Low Dose, IHL-42X High Dose, Placebo, IHL-42X (Optimal Dose), Dronabinol, Acetazolamide; Drug
Lead sponsor: Incannex Healthcare Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 20
States / cities: Chula Vista, California • Long Beach, California • Upland, California + 16 more

Conditions: Insomnia, Ulcerative Colitis
Interventions: CBT-I UC; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Positive-Pressure Respiration, Communication
Interventions: F2S Communicator, Non-functioning Communicator; Device · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold, Depression Disorders, Sleep Disorder
Interventions: AFA-281; Drug
Lead sponsor: Afasci Inc; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alzheimer's Disease
Interventions: Actigraph; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 30 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Sleep Apnea, Sleep Disturbance
Interventions: Couples-based treatment- Patient, Couples-based treatment- Partner, Information control- Patient, Information control- Partner; Behavioral · Other
Lead sponsor: University of Utah; Other
Eligibility: 35 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Tuscon, Arizona • Salt Lake City, Utah

Conditions: Insomnia, Insomnia Chronic
Interventions: SleepSpaceRx CBT-I-IoT-AI, SleepEZ CBTi, Sleep Hygiene IoT; Behavioral
Lead sponsor: Proactive Life Inc; Industry
Eligibility: 55 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Restless Legs Syndrome
Interventions: Topiramate; Drug
Lead sponsor: Neurocare; Other
Eligibility: 18 Years to 70 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Newton, Massachusetts

Conditions: Insomnia
Interventions: Trazodone, Eszopiclone, Placebo; Drug · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 673 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 35
States / cities: Birmingham, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 31 more

Search by objective public record fields.

Sleep Duration Required to Restore Performance During Chronic Sleep Restriction

Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation

Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD

Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2

Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery

RPMO2 Oximeter Accuracy During Sleep 1 Trial

Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.

Respiratory Resistance Training on Sleep Quality in Persons With Spinal Cord Injury

Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)

Improving the Sleep of Cancer Patients Using an Internet-Based Program

Positive Pressure Treatment of Obstructive Sleep Apnea

New Mothers Alpha-Stim

A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005)

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA

Piloting an Insomnia Treatment in Patients With Ulcerative Colitis

Determining the Benefits of Improving Communication in BPAP/CPAP Users

A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

Brain Sleep Deprivation MRI Effects (BEDTIME)

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

Deep Sleep in Older Adults

Efficacy and Safety Study of Topiramate to Treat Restless Legs Syndrome

National Adaptive Trial for PTSD Related Insomnia