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ClinicalTrials.gov public records Last synced Nov 12, 2026, 1:08 PM EST

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Showing 145–168 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Obstructive Sleep Apnea
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2031
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obstructive Sleep Apnea
Interventions: TAK-925, Placebo; Drug
Lead sponsor: Millennium Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 67 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 18
States / cities: Alabaster, Alabama • Glendale, Arizona • Little Rock, Arkansas + 15 more

Conditions: Type 2 Diabetes, Sleep Disordered Breathing
Interventions: Exenatide, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia, Alcohol Use Disorder (AUD), Suicide Ideation
Interventions: Deaf CBT-TS; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Obstructive Sleep Apnea
Interventions: OMT Exercises, Nasal Breathing Exercises, Use of Nasal Lavage; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sleep Apnea, Gastroesophageal Reflux Disease
Interventions: Not listed
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Insomnia
Interventions: Sleep Parent Training (SPT), Sleep Parent Education (SPE); Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 3 Years to 7 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 3
States / cities: Cleveland, Ohio • Columbus, Ohio

Conditions: Chronic Insomnia
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 405 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003
U.S. locations: 25
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Hot Springs, Arkansas + 22 more

Conditions: Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
Interventions: Oral appliance therapy plus scaling and root planing on left or right of mouth; Device
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Anxiety
Interventions: Anxiety Management Education, 10 week tai chi intervention, Enhanced tai chi instruction; Behavioral
Lead sponsor: Appalachian State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boone, North Carolina

Conditions: Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Respiration Disorders, Signs and Symptoms, Respiratory, Syndrome, Obstructive Sleep Apnea
Interventions: aura6000 THN System; Device
Lead sponsor: ImThera Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 4
States / cities: San Diego, California • Denver, Colorado • Chicago, Illinois + 1 more

Conditions: Stress, Quality of Life, Sleep Disturbance
Interventions: Remote health coaching to improve self-care behaviors; Other
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Obstructive Sleep Apnea
Interventions: Upper airway collapsibility (Pcrit); Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 79 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sleep Apnea, Obstructive
Interventions: Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex), Standard polysomnography (PSG); Other
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years and older
Enrollment: 373 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Sleep Apnea, Obstructive, Apnea, Sleep
Interventions: aerSleep II; Device
Lead sponsor: Sommetrics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 15
States / cities: Tucson, Arizona • Little Rock, Arkansas • Los Angeles, California + 10 more

Conditions: Obstructive Sleep Apnea
Interventions: Self-Management Care, Self-Management Mobile Care, Usual Care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 85 Years
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Alzheimer's Disease
Interventions: Actigraph; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 30 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Postpartum Depression, Postpartum Anxiety, Sleep Disturbance, Infant Behavior, Maternal Behavior, Inflammation, Military Family
Interventions: Smart Bassinet, HALO; Device
Lead sponsor: University of Colorado, Colorado Springs; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 342 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Obesity, Sleep Apnea, Obstructive
Interventions: Neurocognitive Testing; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 30 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Stanford, California

Conditions: Obstructive Sleep Apnea, Hypertension
Interventions: Lorundrostat, Placebo; Drug
Lead sponsor: Mineralys Therapeutics Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 27
States / cities: Tuscaloosa, Alabama • Chandler, Arizona • Little Rock, Arkansas + 24 more

Conditions: Restless Legs Syndrome
Interventions: GEn (XP13512/GSK1838262), Placebo; Drug
Lead sponsor: XenoPort, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 217 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Morbid Obesity, Obstructive Sleep Apnea Syndrome, Metabolic Syndrome, Insulin Resistance, Nonalcoholic Fatty Liver Disease
Interventions: Laparoscopic adjustable gastric banding (Allergan Lap Band); Device
Lead sponsor: Jeffrey L Zitsman, MD; Other
Eligibility: 13 Years to 19 Years
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Insomnia, Depression
Interventions: Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 25 Years to 60 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Obstructive Sleep Apnea, Daytime Sleepiness
Interventions: Whole Food Plant-Based Diet; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Jacksonville, Florida

Search by objective public record fields.

Obstructive Sleep Apnea Among Somali-Americans

Study of TAK-925 in Participants With Obstructive Sleep Apnea (OSA) Who Are Experiencing Excessive Daytime Sleepiness (EDS) Despite Adequate Use of Continuous Positive Airway Pressure (CPAP)

Impact of Exenatide on Sleep in Type 2 Diabetes

Deaf CBT-TS to Reduce Suicide Risk

Effect of Myofunctional Therapy on OSA

Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese Patients

Parent-Mediated Telehealth Intervention for Insomnia in Young Autistic Children

Study of Efficacy of Ramelteon in Adults With Chronic Insomnia

Does myTAP Oral Appliance Therapy Including a Mouth Shield Lessen Periodontitis in Mouth-Breathers Who Snore?

Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults

Targeted Hypoglossal Neurostimulation Study #2

Caregiver Protocol for Remotely Improving, Monitoring, and Extending Quality of Life

Determination of Upper Airway Collapsibility During Routine CPAP Titration

Portable Monitoring for Diagnosis and Management of Sleep Apnea

Study Using Negative Pressure to Reduce Apnea

Improving the Frequency and Quality of Sleep Apnea Care Management

Brain Sleep Deprivation MRI Effects (BEDTIME)

Improving Maternal Sleep and Mental Health

The Effect of Obstructive Sleep Apnea on Medical Outcomes After Gastric Bypass Surgery

A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension

Dose-Response and Pharmacokinetics of Gabapentin Enacarbil (GEn [XP13512 / GSK1838262]) in Restless Legs Syndrome

LAGB as a Treatment for Morbid Obesity in Adolescents

A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety

Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea