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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:43 PM EDT

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Showing 1–24 of 454 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stroke, Acute Clear all
Terminated Early Phase 1 Interventional

Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study

NCT04218773
View directory record Official record
Conditions
Ischemic Stroke, Blood Pressure
Interventions
Phenylephrine, Norepinephrine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Completed No phase listed Observational

Telestroke for Comprehensive Stroke Care in Acute Stroke Ready Hospitals

NCT03672890
View directory record Official record
Conditions
Stroke
Interventions
Telestroke
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
551 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
5
States / cities
Burnsville, Minnesota • Grand Rapids, Minnesota • Hibbing, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Not applicable Interventional

Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?

NCT01878968
View directory record Official record
Conditions
Congestive Heart Failure, Infections, Sepsis, Acute Renal Failure, Stroke
Interventions
Script and CPR/Mechanical ventilation video.
Other
Lead sponsor
Jewish Hospital, Cincinnati, Ohio
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Phase 3 Interventional Results available

Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial

NCT01369069
View directory record Official record
Conditions
Acute Ischemic Stroke, Diabetes, Hyperglycemia
Interventions
IV insulin to maintain target glucose concentration of 80-130 mg/dL, Standard Care control - sliding scale insulin to keep glucose less than 180 mg/dL
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
1,151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
70
States / cities
Tucson, Arizona • Long Beach, California • Los Angeles, California + 45 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2019 · Synced Oct 22, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ischemic Conditioning During Air tRansport Save penUmbral Tissue

NCT03481205
View directory record Official record
Conditions
Acute Stroke
Interventions
Ischemic conditioning device
Device
Lead sponsor
Enrique Leira
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 22, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm

NCT01201629
View directory record Official record
Conditions
Brain Infarction, Brain Ischemia
Interventions
t DC stimulation, tDCStimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

A Study to Test the SENSE Device in Patients With Intracranial Hemorrhage

NCT03038087
View directory record Official record
Conditions
Intracerebral Hemorrhage, Stroke, Acute, Stroke Hemorrhagic
Interventions
SENSE Device
Device
Lead sponsor
Sense Diagnostics, LLC
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 22, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Results available

Pilot Randomized Controlled Study of the Impact of MedRhythms' MR-010 in Acute Stroke

NCT04689256
View directory record Official record
Conditions
Stroke, Acute
Interventions
MR-010
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Phase 1Phase 2 Interventional

Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial

NCT00250991
View directory record Official record
Conditions
Stroke
Interventions
activase, integrilin
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
19
States / cities
Phoenix, Arizona • Los Angeles, California • Santa Monica, California + 10 more
Source: ClinicalTrials.gov public record
Updated May 8, 2009 · Synced Oct 22, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional

Impact of Intraoperative Oxygenation Practices on Patient Outcomes

NCT07224243
View directory record Official record
Conditions
Surgeries Undergoing General Anesthesia
Interventions
Lower FiO2, Intermediate FiO2, Higher FiO2
Other
Lead sponsor
Frederic T Billings IV
Other
Eligibility
18 Years and older
Enrollment
54,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Ann Arbor, Michigan • Omaha, Nebraska • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain

NCT05800808
View directory record Official record
Conditions
Cardiac Output, Stroke Volume
Interventions
High Intensity Intervals, Moderate Exercise
Procedure
Lead sponsor
California Baptist University
Other
Eligibility
18 Years to 38 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 22, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Not applicable Interventional

The Application of a Mental Practice Protocol in the Acute Inpatient Rehabilitation Setting

NCT04927728
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Mental Practice, Repetitive-Task Practice, Traditional Therapy
Other
Lead sponsor
Adventist HealthCare
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2021 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Stroke and CPAP Outcome Study: A Sham-controlled Trial of CPAP Among Stroke Rehabilitation Patients

NCT02551757
View directory record Official record
Conditions
Stroke, Sleep Apnea, Obstructive
Interventions
Auto-titrating CPAP, Sham-CPAP
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 22, 2026, 3:43 PM EDT
Terminated Phase 2 Interventional Results available

Fluoxetine for Visual Recovery After Ischemic Stroke

NCT02737930
View directory record Official record
Conditions
Acute Stroke, Visual Field Loss
Interventions
Fluoxetine, Placebo
Drug
Lead sponsor
Bogachan Sahin
Other
Eligibility
18 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Oct 22, 2026, 3:43 PM EDT
Recruiting Phase 3 Interventional

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

NCT04774159
View directory record Official record
Conditions
Peripheral Arterial Disease, Atherosclerosis of Extremities, Inflammation
Interventions
Colchicine 0.5 MG Oral Tablet, Colchicine-Placebo
Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
6,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
24
States / cities
New Haven, Connecticut • Gainesville, Florida • Tampa, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Active, not recruiting Phase 3 Interventional

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial

NCT03496883
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
Recombinant Activated Factor VII (rFVIIa), Placebo
Biological
Lead sponsor
Joseph Broderick, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
51
States / cities
Birmingham, Alabama • Phoenix, Arizona • Baldwin Park, California + 42 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Phase 3 Interventional

Walkbot Robotic Training for Improvement in Gait

NCT03554642
View directory record Official record
Conditions
Ischemic Stroke, Gait, Hemiplegic
Interventions
Walkbot, Physical Therapy
Device · Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 22, 2026, 3:43 PM EDT
Completed No phase listed Observational

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

NCT02014896
View directory record Official record
Conditions
Ischemic Stroke, Atrial Fibrillation, Transient Ischemic Attacks, Transient Cerebrovascular Events, Thrombotic Stroke, Stroke of Basilar Artery, Cardioembolic Stroke
Interventions
Biomarker blood draw
Other
Lead sponsor
Ischemia Care LLC
Industry
Eligibility
18 Years and older
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
22
States / cities
Sacramento, California • San Francisco, California • Detroit, Michigan + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 22, 2026, 3:43 PM EDT
Not yet recruiting Phase 1 Interventional

A Phase 1b Study to Assess the Safety and Tolerability of AB126 Neural Exosomes in Patients With Moderate to Severe Acute Ischemic Stroke

NCT07813130
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
AB126 Neural Exosomes Intravenous Injection, AB126 Placebo
Biological · Other
Lead sponsor
Aruna Bio, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Recruiting Phase 2Phase 3 Interventional

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial

NCT06949228
View directory record Official record
Conditions
Ischemic Stroke, Acute Disease
Interventions
tenecteplase
Drug
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stroke Ready - Optimizing Acute Stroke Care

NCT03645590
View directory record Official record
Conditions
Stroke, Acute, Stroke
Interventions
Stroke Ready
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
5,970 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 22, 2026, 3:43 PM EDT
Completed No phase listed Observational

The Effect of Implementing Hyper-acute Stroke Guidelines on Decision-Making for or Against Thrombolytic Therapy for Stroke in the Emergency Department

NCT01050049
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
19 Years and older
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2010 · Synced Oct 22, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

NCT06094478
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke, Acute, Hemorrhagic Stroke
Interventions
HI-SPEED Protocol
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
8
States / cities
New Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 22, 2026, 3:43 PM EDT