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ClinicalTrials.gov public records Last synced Nov 13, 2026, 2:35 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 262 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Surgical Site Infections Clear all

Conditions: Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
Interventions: 10% povidone-iodine (1% free iodine) in purified water, 4% chlorhexidine gluconate (CHG) in purified water; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 1,638 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 11
States / cities: Phoenix, Arizona • Tucson, Arizona • San Francisco, California + 8 more

Conditions: Surgical Site Infection
Interventions: topical irrigation with gentamicin (80mg diluted in 1L 0.9% normal saline), topical irrigation with sterile normal saline (NS), intravenous (IV) prophylactic antibiotic; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Ventral Hernia
Interventions: Group 1; Device
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Asheville, North Carolina • Charlotte, North Carolina • Greenville, South Carolina

Conditions: Infections
Interventions: E-101 Solution 300 GU/ml, Saline solution; Drug
Lead sponsor: Excited States, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 503 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 34
States / cities: Mobile, Alabama • Los Angeles, California • Stanford, California + 29 more

Conditions: Neurological Diseases
Interventions: "Low O.R. Traffic"; Behavioral
Lead sponsor: St. Joseph's Hospital and Medical Center, Phoenix; Other
Eligibility: 18 Years and older
Enrollment: 1,944 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Surgical Wound Infection, Cesarean Section
Interventions: Prophylactic NPWT, Standard Dressing; Device
Lead sponsor: Indiana University; Other
Eligibility: 16 Years and older · Female only
Enrollment: 1,624 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 6
States / cities: Birmingham, Alabama • Indianapolis, Indiana • New Orleans, Louisiana + 1 more

Conditions: Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
Interventions: Povidone-Iodine, SURGX Wound Gel; Drug · Device
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Wound Infection
Interventions: Purse string closure, Primary closure; Procedure
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Surgical Site Infection, Wound Surgical, Colorectal Disorders
Interventions: Primary Ostomy Closure with 0.1% Betaine/0.1% Polyhexanide Wound Irrigation, Pursestring Closure; Drug · Procedure
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Infections
Interventions: Normal saline pressurized irrigation, sub-q gentamicin; Procedure · Drug
Lead sponsor: Dallas VA Medical Center; Federal
Eligibility: 18 Years to 95 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Abdomen Hernia
Interventions: Prevena, Prineo, Traditional; Device · Drug
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
Interventions: daptomycin; Drug
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 19 Years to 74 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Torrance, California

Conditions: Surgical Site Infection
Interventions: Clindamycin 1% Gel, Benzoyl peroxide 5% gel, BenzaClin 5%-1% Topical Gel; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Fallopian Tube Cancer, Fallopian Tube Infection
Interventions: Aspirin 81 mg; Drug
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Staphylococcal Vaccine
Interventions: Staphylococcus aureus 4-Antigen (SA4Ag) Vaccine, Placebo; Biological · Other
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 3,450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 234
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 89 more

Conditions: Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation, Angina, Deep Vein Thrombosis, Pulmonary Embolism, Respiratory Arrest, Respiratory Failure, Pneumonia, Gastrointestinal Bleed, Stomach Ulcer, Delirium, Stroke, Nerve Injury, Surgical Wound Infection
Interventions: Not listed
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 73,952 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Surgical Site Infections, Stress Hyperglycemia
Interventions: Insulin Lispro Injection, glucose testing; Drug · Diagnostic Test
Lead sponsor: St. Peter's Hospital, Albany, NY; Other
Eligibility: 18 Years and older
Enrollment: 266 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Albany, New York

Conditions: Surgical Site Infection
Interventions: Ertapenem, Cefazolin and Metronidazole.; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Head and Neck Cancer
Interventions: Chlorhexidine Gluconate, Povidone-iodine, Tetracycline Ointment; Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Wound Infection Due to Staphylococcus Aureus, MRSA Infection of Postoperative Wound
Interventions: antiseptic bundle, standard of care; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Surgical Site Infection
Interventions: mupirocin calcium ointment, 2%, 3M Skin and Nasal Antiseptic; Drug
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 1,874 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgical Site Infection
Interventions: Intrasite Vancomycin, IV Vancomycin; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Surgical Wound Infection
Interventions: Vacuum-assisted closure, Standard sterile dressing; Device
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 166 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 4
States / cities: Lebanon, New Hampshire • Nashua, New Hampshire

Conditions: Postoperative Wound Infection-deep, Post Operative Wound Infection
Interventions: RUT058-60, Sterile saline for irrigation; Drug
Lead sponsor: Pulmatrix Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 4
States / cities: Mobile, Alabama • La Jolla, California • Houston, Texas + 1 more

Search by objective public record fields.

Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures

Topical Antibiotic Irrigation (Gentamicin) in Prophylaxis of Midfacial Fracture Surgical Wounds

Microlyte in Prevention of SSI After Open Ventral Hernia Repair

Study to Evaluate Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery

Evaluating the Impact That Personnel Traffic Through the Operating Room Has on Surgical Site Infections

Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial

SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty

A Randomized Trial of Ostomy Closure Techniques

Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure

Effectiveness for Interventions to Minimize Surgical Site Infections

The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR

Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery

Topical Treatment and Prevalence of P. Acnes

Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys

Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications

PRevention Of Trauma-related Infections Through an Embedded Clinical Trials Network

Topical Antisepsis in Head and Neck Cancer Surgery

S. Aureus Screening and Decolonization

Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin

Dose Escalation Trial of Intrasite Vancomycin Pharmacokinetics

Vacuum Assisted Closure for Cesarean Section

A Phase I/II Double-Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of RUT058-60