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ClinicalTrials.gov public records Last synced Oct 10, 2026, 1:37 PM EDT

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Showing 49–72 of 87 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Thoracic Aorta Aneurysm Clear all
Approved For Marketing No phase listed Expanded access

Zenith® Dissection Endovascular System in the Treatment of Patients With Aortic Dissections

NCT02464943
View directory record Official record
Conditions
Aortic Dissection
Interventions
Endovascular Treatment (Zenith)
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
3
States / cities
Camden, New Jersey • Pittsburgh, Pennsylvania • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 10, 2026, 1:37 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

VALOR: The Talent Thoracic Stent Graft System Clinical Study

NCT00604799
View directory record Official record
Conditions
Thoracic Aortic Aneurysms
Interventions
Talent Thoracic Stent Graft
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 10, 2026, 1:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes

NCT02213484
View directory record Official record
Conditions
Marfan Syndrome, Loeys-Dietz Syndrome, Thoracic Aortic Aneurysm and Dissection Syndromes, Ehlers-Danlos Type IV Syndrome, Turner Syndrome
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Days to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Oct 10, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional

MBA Early Feasibility Study

NCT07564375
View directory record Official record
Conditions
Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Thoracic Aortic Dissection, Pseudoaneurysm
Interventions
GORE® Multibranch Arch Endoprosthesis, GORE® Ascending Stent Graft
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
3
States / cities
Los Angeles, California • Cleveland, Ohio • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Active, not recruiting No phase listed Observational

Pathogenetic Basis of Aortopathy and Aortic Valve Disease

NCT03440697
View directory record Official record
Conditions
Aortopathies, Thoracic Aortic Aneurysm, Aortic Valve Disease, Thoracic Aortic Disease, Thoracic Aortic Dissection, Thoracic Aortic Rupture, Ascending Aortic Disease, Descending Aortic Disease, Ascending Aortic Aneurysm, Descending Aortic Aneurysm, Marfan Syndrome, Loeys-Dietz Syndrome, Vascular Ehlers-Danlos Syndrome, Shprintzen-Goldberg Syndrome, Turner Syndrome, PHACE Syndrome, Autosomal Recessive Cutis Laxa, Congenital Contractural Arachnodactyly, Arterial Tortuosity Syndrome, Bicuspid Aortic Valve-Associated Aortopathy, Bicuspid Aortic Valve, Familial Thoracic Aortic Aneurysm and Aortic Dissection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2030
U.S. locations
2
States / cities
Atlanta, Georgia • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional

Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies

NCT02043691
View directory record Official record
Conditions
Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Penetrating Aortic Ulcer, Aortic Arch Aneurysm, Aortic Dissection
Interventions
Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft, Surgeon-Modified Endograft
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Completed Not applicable Interventional

STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft

NCT00111176
View directory record Official record
Conditions
Thoracic Aortic Aneurysm
Interventions
Endovascular repair, Surgical
Device · Procedure
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
38
States / cities
Mesa, Arizona • Phoenix, Arizona • San Francisco, California + 28 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2014 · Synced Oct 10, 2026, 1:37 PM EDT
Not listed Not applicable Interventional

Clinical Study of Thoracic Aortic Aneurysm Exclusion

NCT00549315
View directory record Official record
Conditions
Thoracic Aortic Aneurysm
Interventions
Valiant Endoluminal Stent-Graft Stent-Graft Balloon Catheter
Device
Lead sponsor
Arizona Heart Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 15, 2009 · Synced Oct 10, 2026, 1:37 PM EDT
Terminated Not applicable Interventional Results available

Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)

NCT00805948
View directory record Official record
Conditions
Thoracic Aortic Aneurysms
Interventions
Talent Thoracic Stent Graft System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
26
States / cities
Los Angeles, California • Torrance, California • Washington D.C., District of Columbia + 22 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 10, 2026, 1:37 PM EDT
Completed No phase listed Observational

Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR

NCT01480206
View directory record Official record
Conditions
Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA), Carotid Stenosis, Visceral Artery Aneurysm
Interventions
Endovascular Aortic Repair (EVAR)
Other
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 90 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 10, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT06377033
View directory record Official record
Conditions
Genetic Predisposition, Paraganglioma, Pheochromocytoma, ALS, Parkinson Disease, Polyneuropathies, Frontotemporal Dementia, Alzheimer Disease, Cardiomyopathy Non-ischemic, Thoracic Aortic Aneurysm
Interventions
Behavioral nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Terminated Not applicable Interventional Results available

The Effect of Losartan in Bicuspid Aortic Valve Patients

NCT01390181
View directory record Official record
Conditions
Bicuspid Aortic Valve, Thoracic Aortic Aneurysm
Interventions
Cozaar
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Oct 10, 2026, 1:37 PM EDT
Active, not recruiting Not applicable Interventional

RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers

NCT02818972
View directory record Official record
Conditions
Aortic Aneurysm, Thoracic, Penetrating Ulcer
Interventions
RelayPro
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
24
States / cities
Birmingham, Alabama • Phoenix, Arizona • Irvine, California + 17 more
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 10, 2026, 1:37 PM EDT
Recruiting Phase 1Phase 2 Interventional

HEART: Pilot Randomized Controlled Trial

NCT07483177
View directory record Official record
Conditions
Thoracic Aortic Aneurysm
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Not listed Phase 1 Interventional

ENTRUST - TAArget® Thoracic Stent Graft Clinical Trial

NCT01033214
View directory record Official record
Conditions
Thoracic Aortic Aneurysm
Interventions
Endovascular repair of TAA in the descending Thoracic Aorta
Device
Lead sponsor
Duke Vascular, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Newark, Delaware • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Oct 10, 2026, 1:37 PM EDT
Active, not recruiting No phase listed Observational

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)

NCT05082454
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
Open repair
Device
Lead sponsor
JOTEC GmbH
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
3
States / cities
Danville, Pennsylvania • Houston, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 10, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional

CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft

NCT02089607
View directory record Official record
Conditions
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
Interventions
CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
Device
Lead sponsor
Gustavo S Oderich
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2032
U.S. locations
3
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Completed Not applicable Interventional Results available

Phase II Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft

NCT00435942
View directory record Official record
Conditions
Thoracic Aortic Aneurysms, and Penetrating Atherosclerotic Ulcers
Interventions
Relay Thoracic Stent-Graft, Open Repair
Device · Procedure
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
27
States / cities
Phoenix, Arizona • Tucson, Arizona • San Francisco, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 10, 2026, 1:37 PM EDT
Completed Phase 2 Interventional Results available

Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair

NCT01920594
View directory record Official record
Conditions
Surgical Procedures
Interventions
GSK1278863, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
13
States / cities
Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 10, 2026, 1:37 PM EDT
Terminated No phase listed Observational

The CardiOvascular Remodeling Following Endovascular Aortic Repair (CORE) Study

NCT02735720
View directory record Official record
Conditions
Thoracic Aortic Aneurysm
Interventions
TEVAR, Non-TEVAR medical treatment
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 10, 2026, 1:37 PM EDT
Recruiting Not applicable Interventional

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

NCT04471909
View directory record Official record
Conditions
Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
Interventions
NEXUS Aortic Stent Graft System
Device
Lead sponsor
Endospan Ltd.
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
31
States / cities
Birmingham, Alabama • La Jolla, California • Sacramento, California + 27 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 10, 2026, 1:37 PM EDT
Enrolling by invitation Not applicable Interventional

Evaluation of the GORE® Ascending Stent Graft

NCT05800743
View directory record Official record
Conditions
Aortic Aneurysm, Thoracic, Pseudoaneurysm, Aortic Dissection, Aorta; Lesion
Interventions
GORE® Ascending Stent Graft (ASG device), GORE® Thoracic Aortic Graft Thoracic Branch Endoprosthesis (TBE Device), Surgery
Device · Procedure
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
41
States / cities
Birmingham, Alabama • Long Beach, California • Los Angeles, California + 37 more
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 10, 2026, 1:37 PM EDT
Completed Not applicable Interventional

Development of Ultra-Low Dose CT Based Screening for Aortic Aneurysms

NCT03479164
View directory record Official record
Conditions
Aortic Aneurysm, Thoracic, Aortic Aneurysm, Abdominal
Interventions
Ultra Low-Dose CT
Other
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Oct 10, 2026, 1:37 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of Valiant Mona LSA Stent Graft System

NCT01839695
View directory record Official record
Conditions
Thoracic Aortic Aneurysms
Interventions
Valiant Mona LSA Stent Graft System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Charlotte, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 10, 2026, 1:37 PM EDT