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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:39 AM EDT

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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Upper GI Symptoms Clear all
Completed Phase 3 Interventional

Esomeprazole for Relief of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs

NCT00241540
View directory record Official record
Conditions
GERD
Interventions
Esomeprazole
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
808 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
19
States / cities
Tucson, Arizona • Anaheim, California • Orange, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2011 · Synced Oct 23, 2026, 6:39 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Metoclopramide in Upper Gastrointestinal Bleed

NCT05746377
View directory record Official record
Conditions
Upper GI Bleeding, Bleeds Gastric, Bleed Ulcer, Hemorrhage Gastric, Hemorrhage; Ulcer
Interventions
Metoclopramide 10mg, Saline
Drug
Lead sponsor
Mercy Health System
Network
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rockford, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 23, 2026, 6:39 AM EDT
Active, not recruiting No phase listed Observational

Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease

NCT00260572
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
Questionnaires to evaluate QOL, Questionnaires to evaluate heartburn and quality of life, Questionnaire to evaluate satisfaction with treatment, Questionnaire to evaluate presence or absence of pain
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2050
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 6:39 AM EDT
Not listed No phase listed Observational

Pediatric Acute Gastrointestinal Bleeding Registry

NCT03090945
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding, Gastro Intestinal Bleeding
Interventions
This is an obsevational cohort study
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Chicago, Illinois • Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Phase 2 Interventional

The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.

NCT00303264
View directory record Official record
Conditions
Dyspepsia
Interventions
dexloxiglumide, Nexium (esomeprazole)
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 5, 2012 · Synced Oct 23, 2026, 6:39 AM EDT
Recruiting Not applicable Interventional

Trans-nasal Endoscopy for Bariatric Patients

NCT06200961
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obese, GI Disorders, Gastrointestinal Diseases
Interventions
Transnasal Endoscopy, Esophagogastroduodenoscopy
Device · Procedure
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 23, 2026, 6:39 AM EDT
Recruiting Not applicable Interventional

Treatment of Upper Gastrointestinal Symptoms Using Hypnotherapy Sessions

NCT06846359
View directory record Official record
Conditions
GI Symptoms
Interventions
Hypnotherapy, Educational module
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Low Dose Upper Abdominal Radiation Therapy (LD-UART) + Gemcitabine in Patients With Advanced, Unresectable Pancreatic Cancer (PC)

NCT00390182
View directory record Official record
Conditions
Gastrointestinal Neoplasms, Ovarian Neoplasms
Interventions
Gemcitabine
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 23, 2026, 6:39 AM EDT
Completed No phase listed Observational

An Observational Study of Burden of Upper GI-Symptoms in CV Risk Patients

NCT00681759
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Not listed
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
1,836 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Brentwood, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 31, 2008 · Synced Oct 23, 2026, 6:39 AM EDT
Terminated Phase 2 Interventional Results available

Study of orBec® as Monotherapy in the Treatment of Patients With Upper GI Symptoms Caused by Chronic Graft Versus Host Disease (GVHD)

NCT01925950
View directory record Official record
Conditions
Chronic Gastrointestinal Graft vs Host Disease
Interventions
orBec, Placebo
Drug
Lead sponsor
Soligenix
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Hackensack, New Jersey • Buffalo, New York • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Not applicable Interventional Results available

Presence or Absence of Blood in the GI Lumen

NCT05415124
View directory record Official record
Conditions
Upper GI Bleeding
Interventions
HemoPill, Endoscopy
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Oct 23, 2026, 6:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule

NCT00579410
View directory record Official record
Conditions
Esophagitis, Inflammation, Gastritis, Abdominal Pain, Heartburn
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 22, 2011 · Synced Oct 23, 2026, 6:39 AM EDT
Terminated Phase 4 Interventional

Effect of Tegaserod on Gastric Emptying in Patients With Diabetic Gastroparesis

NCT00390975
View directory record Official record
Conditions
Gastroparesis, Diabetes
Interventions
Tegaserod
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
3
States / cities
Kansas City, Kansas • Louisville, Kentucky • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2012 · Synced Oct 23, 2026, 6:39 AM EDT
Completed No phase listed Observational

Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy

NCT05763745
View directory record Official record
Conditions
Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content, GI Bleed
Interventions
Point of Care Ultrasound
Diagnostic Test
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Capsule Endoscopy for HEmorrhage in the ER

NCT03458000
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding
Interventions
PillCam UGI, Standard of Care
Device · Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Oct 23, 2026, 6:39 AM EDT
No Longer Available No phase listed Expanded access

The Use Of Domperidone For The Relief Of Refractory Upper Gastrointestinal GI Symptoms

NCT03810287
View directory record Official record
Conditions
Gastroparesis
Interventions
Domperidone
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 23, 2026, 6:39 AM EDT
Enrolling by invitation No phase listed Observational

PillSense Use in Anemia and Hemoccult

NCT06951490
View directory record Official record
Conditions
Occult Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding (UGIB)
Interventions
PillSense™
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 23, 2026, 6:39 AM EDT
Withdrawn Not applicable Interventional

Validation of Esophageal Variceal Grading: A Comparative Study of Upper Gastrointestinal (GI) Endoscopy and Capsule Endoscopy

NCT00475592
View directory record Official record
Conditions
Esophageal and Gastric Varices
Interventions
Esophageal Capsule Endoscopy, Upper Gastrointestinal Endoscopy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 23, 2026, 6:39 AM EDT
Recruiting Not applicable Interventional

Detection of Blood in the GI Lumen With HemoPill Acute

NCT07868068
View directory record Official record
Conditions
Upper GI Bleeding
Interventions
HemoPill acute
Device
Lead sponsor
Stony Brook University
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 23, 2026, 6:39 AM EDT
Terminated Phase 2 Interventional Results available

P:II Above-Label Octreotide-LAR With Insufficiently Controlled Carcinoid Syndrome

NCT01886287
View directory record Official record
Conditions
Neuroendocrine Carcinoma
Interventions
Octreotide LAR
Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Not applicable Interventional

Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)

NCT06732453
View directory record Official record
Conditions
Functional Dyspepsia, Gastroparesis
Interventions
Seated Yoga Skills Training in Functional Dyspepsia and Gastroparesis (FD-GP)
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Phase 3 Interventional

Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill

NCT00045799
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding
Interventions
Omeprazole sodium bicarbonate immediate release PWD/FS, Cimetidine IV
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
16 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
58
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 49 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 23, 2026, 6:39 AM EDT
Terminated Not applicable Interventional Results available

Randomized Control Trial Comparing Prokinetics and Their Influence on Endoscopy Outcomes for Upper GI Bleed.

NCT02017379
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding
Interventions
Erythromycin, Metoclopromide
Drug
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 23, 2026, 6:39 AM EDT
Completed Phase 3 Interventional

Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs

NCT00241514
View directory record Official record
Conditions
GERD
Interventions
Esomeprazole
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
19
States / cities
Tucson, Arizona • Anaheim, California • Orange, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2011 · Synced Oct 23, 2026, 6:39 AM EDT