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Showing 169–192 of 680 matching trials from the local directory fallback.
Conditions
Cardiovascular Diseases (CVD), Dietary Fiber, Gastrointestinal Microbiome, Insulin Resistance, Inulin, Microbiota, Muscle, Skeletal, Obesity & Overweight, Perimenopausal Women, Prebiotics, Vascular Health, Women Health
Interventions
Inulin, Maltodextrin (Placebo)
Dietary Supplement
Lead sponsor
George Washington University
Other
Eligibility
40 Years to 55 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Aneurysmal Subarachnoid Hemorrhage, Endovascular Treatment, Transcutaneous Vagal Nerve Stimulation (tVNS), Vasospasm, Cerebral
Interventions
Transcutaneous Vagal Nerve Stimulation
Device
Lead sponsor
Marshall Holland
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Recruiting Not applicable Interventional

COMPARE-VENT Feasibility Pilot Study

NCT07656259
Conditions
Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Cardiogenic Shock, Cardiopulmonary, Critical Illness, Mechanical Ventilation, Respiration Failure
Interventions
Pressure Controlled Mode, Volume Controlled Mode
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Cardiovascular Health, Cognitive Health, DHA and EPA Blood Levels, Omega-3 Deficiency
Interventions
Omega Active Supplement
Dietary Supplement
Lead sponsor
Revive Active
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Recruiting Not applicable Interventional Accepts healthy volunteers

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

NCT06476795
Conditions
Adiposity, Cardiometabolic Syndrome, Cardiovascular Diseases
Interventions
Chardonnay Marc
Other
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Davis, California
Conditions
Cardiovascular, Cardiovascular Disease, Chronic Kidney Diease, Chronic Obstructive Pulmonary Disease (COPD), Comorbidity, Diabetes, Inflammatory Joint Diseases
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 99 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Age-Related Macular Degeneration, Choroidal Neovascularization, Macular Degeneration, Wet Macular Degeneration
Interventions
Aflibercept, Tiespectus
Drug
Lead sponsor
EyeBiotech Ltd.
Industry
Eligibility
50 Years and older
Enrollment
960 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
52
States / cities
Gilbert, Arizona • Encino, California • Mountain View, California + 49 more
Conditions
Brain Disease, Endothelial Dysfunction, Kidney Injury, Vascular Diseases, Vascular Inflammation
Interventions
Placebo, Vericiguat
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD
Interventions
Ixo-vec
Genetic
Lead sponsor
Adverum Biotechnologies, Inc.
Industry
Eligibility
50 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
12
States / cities
Phoenix, Arizona • Bakersfield, California • Fullerton, California + 8 more
Recruiting No phase listed Observational Accepts healthy volunteers

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

NCT06029933
Conditions
Cardiovascular Events, Community-acquired Pneumonia, Influenza
Interventions
Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4), High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)
Biological
Lead sponsor
Kaiser Permanente
Other
Eligibility
65 Years and older
Enrollment
1,500,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Oakland, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep Duration and Cardiovascular Health

NCT04804124
Conditions
Cardiovascular Risk Factor, Sleep
Interventions
Regularized Sleep Schedule
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Adipocytic Neoplasm, Angiomatoid Fibrous Histiocytoma, Angiosarcoma, Atypical Fibroxanthoma, Clear Cell Sarcoma, Dedifferentiated Liposarcoma, Dermatofibrosarcoma Protuberans, Fibrosarcomatous, Epithelioid Hemangioendothelioma, Epithelioid Sarcoma, Extraskeletal Myxoid Chondrosarcoma, Fibrosarcoma NOS, Giant Cell Tumor of Soft Parts NOS, Glomus Tumor, Granular Cell Tumor, Malignant, Inflammatory Leiomyosarcoma, Intimal Sarcoma, Leiomyosarcoma, Liposarcoma, Low Grade Fibromyxoid Sarcoma, Low Grade Myofibroblastic Sarcoma, Malignant Peripheral Nerve Sheath Tumor, Malignant Tenosynovial Giant Cell Tumor of Soft Tissue, Melanotic Malignant Nerve Sheath Tumor, Myoepithelial Carcinoma, Myoepithelioma, Myxofibrosarcoma, Myxoid Liposarcoma, Myxoid Pleomorphic Liposarcoma, NTRK-Rearranged Spindle Cell Neoplasm, Ossifying Fibromyxoid Tumor, Malignant, Osteosarcoma, Extraskeletal, Perineurioma, Malignant, Perivascular Epithelioid Tumor, Malignant, Phosphaturic Mesenchymal Tumor, Malignant, Pleomorphic Liposarcoma, Pleomorphic Sarcoma, Undifferentiated, Round Cell Sarcoma, Round Cell Sarcoma, Undifferentiated, Sclerosing Epithelioid Fibrosarcoma, Synovial Sarcoma, Undifferentiated Sarcoma, Well Differentiated Liposarcoma
Interventions
Doxorubicin, Ifosfamide, Pazopanib, Proton beam radiation therapy, Selinexor, Surgical resection
Drug · Radiation · Procedure
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 30 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2037
U.S. locations
7
States / cities
Atlanta, Georgia • Chicago, Illinois • Baton Rouge, Louisiana + 4 more
Recruiting No phase listed Observational Accepts healthy volunteers

Longitudinal Validation of CIRC Technologies

NCT07081711
Conditions
Aortic Diseases, Atrial Fibrillation, Cardiovascular Diseases, Congenital Heart Disease, Heart Failure, Ischemic Heart Disease, Metabolic Cardiomyopathy, Non-ischemic Cardiomyopathy, Valvular Heart Disease, Ventricular Fibrillation
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2037
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factors
Interventions
Not listed
Lead sponsor
University of Oxford
Other
Eligibility
18 Years to 99 Years
Enrollment
250,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
12
States / cities
Phoenix, Arizona • New Haven, Connecticut • Tampa, Florida + 8 more
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

NCT05946785
Conditions
Gestational Diabetes, Vascular Endothelial Function
Interventions
Acetylcholine, insulin aspart
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Energy Expenditure, Insulin Sensitivity/Resistance, Metabolic Disease, Metabolism, Natriuretic Peptides
Interventions
Exercise capacity VO2 maximum determination, Intravenous Glucose Tolerance Test, Sacubitril, Valsartan 97-103 mg Oral Tablet, Standardized Meals, Valsartan 160 mg
Other · Drug · Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Anxiety, Cardiovascular Diseases, Caregiver Burden, Depression, Stress
Interventions
Confident Caregiver Intervention
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sacramento, California
Conditions
Cardiovascular Diseases, Depression
Interventions
BA-HT, Standard Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Cardiovascular Diseases
Interventions
d-Coaching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
San Francisco, California • Decatur, Georgia
Conditions
Cardiovascular Disease Risk Factor, Obese Adolescents, Obesity and Overweight, Weight Loss, Weight Management
Interventions
Ozempic®
Drug
Lead sponsor
John Bauer
Other
Eligibility
12 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Recruiting Not applicable Interventional

Cereset Research Exploratory Study

NCT03777267
Conditions
Cardiovascular Conditions After Birth, Neurological Diseases or Conditions, Psychophysiologic Disorders
Interventions
Active CR
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Cardiovascular Diseases, Obesity
Interventions
PREVENT Tool, Wait-List Control
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Recruiting No phase listed Observational Accepts healthy volunteers

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

NCT06259292
Conditions
Arteriovenous Malformations, Cerebral Arteriovenous Malformations, Epistaxis, GastroIntestinal Bleeding, Hereditary Hemorrhagic Telangiectasia, Telangiectasia, Vascular Malformation
Interventions
Not listed
Lead sponsor
Cure HHT
Other
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2033
U.S. locations
16
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 13 more
Conditions
Cardiovascular, Tumor
Interventions
Not listed
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Houston, Texas