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Conditions: Liver Disease, Hyponatremia
Interventions: conivaptan hydrochloride; Drug
Lead sponsor: Cumberland Pharmaceuticals; Industry
Eligibility: 30 Years to 70 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Surgical Wound Dehiscence, Traumatic Wounds
Interventions: Study Device Debridement, SOC Debridement; Device
Lead sponsor: Medaxis, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Bradenton, Florida

Conditions: Colonoscopy Education
Interventions: Not listed
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: Water prescription; Other
Lead sponsor: University of Kansas; Other
Eligibility: 18 Years to 50 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Pneumothorax, Trauma
Interventions: Inital water seal, Initial suction; Procedure
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Autosomal Dominant Polycystic Kidney
Interventions: High Water Intake; Other
Lead sponsor: The Rogosin Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Mass Casualty Incident, Dehydration
Interventions: hypodermoclysis via recombinant hyaluronidase-facilitated subcutaneous infusion; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Wound Infection Rate
Interventions: wound irrigation with study fluid; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 12 Months and older
Enrollment: 660 participants
Timeline: 1994 – 1996
U.S. locations: 1
States / cities: Stanford, California

Conditions: Dehydration, Head & Neck Cancer, Esophageal Cancer
Interventions: Gatorade G2, Standard of care nutritional support; Dietary Supplement
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Colorectal Neoplasms
Interventions: Indigo carmine, water (exchange) method, water (exchange) plus dye method, air method; Drug · Procedure
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 45 Years to 75 Years
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Obesity
Interventions: Healthy Drinks, Healthy Futures; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 2 Years to 105 Years
Enrollment: 1,034 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Stanford, California

Conditions: Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:; Drug
Lead sponsor: Daniel Benjamin; Other
Eligibility: Up to 21 Years
Enrollment: 3,520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 43
States / cities: Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more

Conditions: Reactions to Warnings, Hookah Smoking
Interventions: Ads Only, Ads with text-only health warning labels (HWLs), Ads with text + graphic health warning labels (HWLs); Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 34 Years
Enrollment: 2,588 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Recovery, Physiological, Athletic Performance
Interventions: Cold water immersion pool.; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Dehydration
Interventions: Exercise Intervention; Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
Interventions: tolvaptan, Fluid Restriction; Drug · Other
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 56
States / cities: Birmingham, Alabama • Mobile, Alabama • Azusa, California + 46 more

Conditions: Geriatric Population
Interventions: Education with a regular hydration opportunity; Behavioral
Lead sponsor: Duquesne University; Other
Eligibility: 60 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Cornwall, Pennsylvania

Conditions: Euvolemic Hyponatremia, Hypervolemic Hyponatremia
Interventions: Not listed
Lead sponsor: Otsuka America Pharmaceutical; Industry
Eligibility: 18 Years and older
Enrollment: 5,028 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 72
States / cities: Azusa, California • Inglewood, California • Los Angeles, California + 58 more

Conditions: Hyponatremia, Inappropriate ADH Syndrome
Interventions: Satavaptan, placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Water, Child Nutrition, Family Dynamics, Healthy Nutrition, Healthy Lifestyle, Health-Related Behavior, Obesity Prevention
Interventions: Water is K'é; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 2 Years and older
Enrollment: 1,160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Window Rock, Arizona

Conditions: Influenza
Interventions: PanBlok, rHA adjuvant; Biological
Lead sponsor: Protein Sciences Corporation; Industry
Eligibility: 18 Years to 49 Years
Enrollment: 341 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 5
States / cities: Omaha, Nebraska • Rochester, New York • Austin, Texas + 2 more

Conditions: Dehydration
Interventions: 5% Dextrose (D5) in Normal Saline (NS), Normal Saline (NS); Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Months to 12 Years
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Acute Decompensated Heart Failure
Interventions: High-dose furosemide, Low-dose furosemide, Low-dose furosemide combined with low-dose dopamine; Drug
Lead sponsor: Larissa University Hospital; Other
Eligibility: 18 Years and older
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Atlanta, Georgia • Cleveland, Ohio

Conditions: Breast Cancer
Interventions: 'R' (Electro-kinetically altered beverage), Placebo (water); Other
Lead sponsor: South Sound Care Foundation; Other
Eligibility: 18 Years and older · Female only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 6
States / cities: Bonney Lake, Washington • Federal Way, Washington • Gig Harbor, Washington + 3 more

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Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function

Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center

Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy

Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Suction Versus Water Seal for Initial Treatment of Traumatic Pneumothorax Trial

A Clinical Trial of Water Therapy for Autosomal Dominant Polycystic Kidney Disease

Recombinant Hyaluronidase in Out-of-Hospital Setting: The EASI Access Trial

Tap Water Versus Normal Saline for Wound Irrigation

DRIHNC - Dehydration Reduction in Head & Neck Cancer

Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)

Childcare Healthy Beverage Access, Food and Beverage Intake, and Obesity

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Reactions to Warnings on Hookah Ads

The Effect of Cold Water Immersion on Recovery and Performance in NCAA Division I Athletes

Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)

Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia

Thirst for Knowledge

Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia

A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia

Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families

Safety and Immunogenicity of PanBlok Influenza Vaccine in Healthy Adults

IV Glucose for Dehydration Treatment

Dopamine in Acute Decompensated Heart Failure II

Effects of 'R' (Electro-kinetic Beverage) on Insomnia, Fatigue, and Depression in Breast Cancer Patients Having Adjuvant Chemo