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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:39 AM EDT

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Showing 265–288 of 1,735 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Loss Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)

NCT06875622
View directory record Official record
Conditions
Obesity/therapy
Interventions
Automated online weight loss program, Individual coaching, Group-based, videoconference-delivered weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional

Vitamin D to Improve Glucose Metabolism and Reduce Inflammation in Obese Adolescents

NCT00994396
View directory record Official record
Conditions
Obesity, Glucose Intolerance, Inflammation
Interventions
Placebo, Vitamin D 3 cholecalciferol
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
9 Years to 19 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Oct 20, 2026, 2:39 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study of How Exercise or Weight Loss Effects Metabolic Syndrome

NCT00292994
View directory record Official record
Conditions
Metabolic Syndrome, Insulin Resistance, Obesity
Interventions
Exercise, Weight Loss
Behavioral
Lead sponsor
Yankton Clinical Research Alliance
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Yankton, South Dakota
Source: ClinicalTrials.gov public record
Updated Feb 16, 2006 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Self-Monitoring Feedback for the Treatment of Obesity

NCT06508580
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Component 1: Calorie Goal Attainment, Component 2: Diet Quality, Component 3: Physical Activity Goal Attainment, Component 4: Goal Setting
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Phase 3 Interventional

Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy

NCT02330926
View directory record Official record
Conditions
Cachexia, Neoplasms
Interventions
standard care, nutritional supplements and advice, home-based self-assisted exercise program, Ibuprofen
Other · Dietary Supplement · Behavioral + 1 more
Lead sponsor
Norwegian University of Science and Technology
Other
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional

Feasibility of High Levels of Energy Expenditure From Physical Activity for Breast Cancer Survivors

NCT02963740
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Supervised Exercise, Home-based Exercise, Group Phone Calls, Diet
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
Up to 71 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 20, 2026, 2:39 AM EDT
Completed No phase listed Observational

Pragmatic Weight Loss Intervention During Menopause

NCT04487782
View directory record Official record
Conditions
Menopause, Menopause Related Conditions
Interventions
Focus Groups
Other
Lead sponsor
Kara Marlatt
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
55 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Calorie Deprivation on Adipose Tissue Distribution

NCT01658397
View directory record Official record
Conditions
Healthy
Interventions
Fasting
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Efficacy and Safety of CX11 Tablets in Overweight/Obese Participants

NCT07011797
View directory record Official record
Conditions
Obesity
Interventions
CX11, Placebo
Drug · Other
Lead sponsor
Corxel Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
17
States / cities
Phoenix, Arizona • Inglewood, California • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults

NCT05388318
View directory record Official record
Conditions
Midlife Obese Adults With Cognitive Decline
Interventions
Prolonged nightly fasting, Health Education Control
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
40 Years to 59 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity

NCT05107908
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Active Implicit Priming, Control Implicit Priming, Food Exposure Task
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 2:39 AM EDT
Active, not recruiting Phase 2 Interventional

A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight

NCT07662122
View directory record Official record
Conditions
Obesity, Overweight
Interventions
BI 3034701, Placebo matching BI 3034701
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years to 74 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • West Hills, California • Miami, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 2:39 AM EDT
Recruiting Phase 3 Interventional

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

NCT07533175
View directory record Official record
Conditions
Diabetes Mellitus, Overweight, Obesity
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
15
States / cities
Birmingham, Alabama • Escondido, California • Lomita, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional

Food is Medicine: Pilot Study

NCT06797453
View directory record Official record
Conditions
Weight Loss
Interventions
Shared Medical Visits, Full Plate Living
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional

GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss

NCT03254953
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
self-monitoring of body weight, self-monitoring of diet, weekly personalized feedback + lessons + action plans
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 20, 2026, 2:39 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Living After Knee Replacement

NCT05190666
View directory record Official record
Conditions
Arthroplasty, Overweight and Obesity
Interventions
PACE Weight Loss program, Chronic Disease Self-Management
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
Not listed
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Gut-brain Axis: a Novel Target for Treating Behavioral Alterations in Obesity

NCT01976156
View directory record Official record
Conditions
Neural Response in Caudate, Weight Loss Trial, Impulsivity
Interventions
PhosphoLean, Placebo
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Oct 20, 2026, 2:39 AM EDT
Completed No phase listed Observational

A Study of the Pre- and Post-operative Semen Analyses and Reproductive Hormone Levels of Men Undergoing Weight-reduction Surgery

NCT00596739
View directory record Official record
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 20, 2026, 2:39 AM EDT
Terminated Phase 3 Interventional Results available

Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass

NCT00394212
View directory record Official record
Conditions
Obesity
Interventions
Transoral Suturing, Sham Endoscopy
Device · Other
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
10
States / cities
Denver, Colorado • Baltimore, Maryland • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2016 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Phase 3 Interventional

A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight

NCT06131437
View directory record Official record
Conditions
Obesity
Interventions
Cagrilintide, Semaglutide, Tirzepatide
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
809 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
46
States / cities
Birmingham, Alabama • Montgomery, Alabama • Costa Mesa, California + 39 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional

Study of Five Different Methods Of Delivering A Lifestyle Modification Program for Weight Loss

NCT00471172
View directory record Official record
Conditions
Obesity
Interventions
Face-to-face counseling by a dietitian (months 1-3: weekly, months 4-6: every other week), Face-to-face counseling by a dietitian (monthly), Counseling by a dietitian via telephone (months 1-3: weekly, months 4-6: every other week), Counseling by a dietitian via e-mail (months 1-3: weekly, months 4-6: every other week), Self help
Behavioral
Lead sponsor
Pfizer
Industry
Eligibility
25 Years to 60 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
12
States / cities
Los Angeles, California • Clearwater, Florida • Kissimmee, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2008 · Synced Oct 20, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise and Weight Loss on Cardiovascular Health

NCT01500356
View directory record Official record
Conditions
Cardiovascular Disease, Obesity
Interventions
Behavioral weight loss intervention, Diet Plus Moderate Exercise, Diet Plus High Exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Oct 20, 2026, 2:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Urobilinogen, Maternal Weight Loss and Impending Parturition at Term

NCT00826605
View directory record Official record
Conditions
Increase in Urobilinogen in Urine Prior to Delivery, Weight Loss After 37 Weeks Gestation Prior to Delivery
Interventions
Not listed
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years to 34 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
2
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 28, 2010 · Synced Oct 20, 2026, 2:39 AM EDT