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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Weight Loss Maintenance Clear all
Completed Not applicable Interventional

mDiet: A Text Message Intervention for Weight Loss

NCT01171586
View directory record Official record
Conditions
Overweight, Weight Loss
Interventions
mDiet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 60 Years
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Jun 10, 2026, 2:27 PM EDT
Recruiting Phase 3 Interventional

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

NCT07503210
View directory record Official record
Conditions
Obesity
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
13
States / cities
Anniston, Alabama • Walnut Creek, California • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 1

NCT04605653
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Diet Habit
Interventions
Weight Management Intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Partnerships to Overcome Obesity Disparities in Hawaii: 18-month CBPR Study

NCT01093924
View directory record Official record
Conditions
Obesity
Interventions
PILI 'Ohana 18-month weight loss maintenance
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eat Well for Life: A Weight Loss Maintenance Study

NCT01849627
View directory record Official record
Conditions
Obesity
Interventions
Low-ED, Energy Balance
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 70 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jun 10, 2026, 2:27 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

International Weight Control Registry

NCT04907396
View directory record Official record
Conditions
Weight Loss, Overweight, Obesity
Interventions
Not listed
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
7
States / cities
Birmingham, Alabama • Denver, Colorado • Kansas City, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Postpartum Weight Loss and Sleep Amongst Obese Women

NCT01968330
View directory record Official record
Conditions
Obesity, Sleep Disordered Breathing, Weight Loss, Postpartum, Insomnia
Interventions
Go!®to sleep
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2016 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise After Clinically Significant Weight Loss

NCT03685123
View directory record Official record
Conditions
Obesity, Sedentary Lifestyle, Insulin Resistance
Interventions
Physical activity recommendations, Weight maintenance recommendations, OPTIFAST weight loss
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Engaging Motivation for the Prevention of Weight Regain

NCT01169428
View directory record Official record
Conditions
Obesity
Interventions
Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2013 · Synced Jun 10, 2026, 2:27 PM EDT
Not yet recruiting Not applicable Interventional

Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation

NCT07535892
View directory record Official record
Conditions
Weight Loss, GLP - 1, Weight Loss Maintenance, Obesity & Overweight
Interventions
Weight Loss Maintenance Program (Foundational), Mom's Meals, YMCA Membership, SKY Meditation Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jun 10, 2026, 2:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

NCT06785064
View directory record Official record
Conditions
Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
Interventions
Reduced Food Variety (RFV), Home-based Resistance Training (HBRT), Buddy Training and Support (BTS), Acceptance and Commitment (ACT) Workshops
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
544 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity

NCT03560635
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Jun 10, 2026, 2:27 PM EDT
Active, not recruiting Phase 2 Interventional

Effects of Mirtazapine on Appetite in Advanced Cancer Patients

NCT00488072
View directory record Official record
Conditions
Advanced Cancer, Anorexia, Weight Loss, Insomnia
Interventions
Mirtazapine, Placebo
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jun 10, 2026, 2:27 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Mechanistic Insights to Weight Loss Maintenance Through SGLT2 Inhibitors

NCT05885074
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Empagliflozin Arm, Control Arm, Exercise capacity VO2 maximum determination, Exercise Challenge
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care for Our Program

NCT04420936
View directory record Official record
Conditions
Diabetes, Weight Loss, Diet Habit
Interventions
MAINTAIN PRIME Lifestyle Coaching, Control tracking
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Phase 3 Interventional Results available

Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - Maintenance

NCT00781937
View directory record Official record
Conditions
Metabolism and Nutrition Disorder, Obesity
Interventions
liraglutide, placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
27
States / cities
Goodyear, Arizona • Peoria, Arizona • Huntington Beach, California + 22 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Longitudinal Effects of a Commercial Digital Weight Management Program on Weight Loss

NCT06666842
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Noom Weight, Educational Control
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Learn, Engage, Act, Process (LEAP) for MOVE!

NCT02825680
View directory record Official record
Conditions
Obesity
Interventions
Enhanced NCP Support, LEAP
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jun 10, 2026, 2:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Modifying Obesogenic Homes: Impact on Weight Maintenance

NCT00200330
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss treatment, Behavioral and home environment weight loss treatment
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 17, 2007 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

PILI at Work a 5-Year Controlled Intervention Trial: Testing DVD Versus Group Delivery of a Weight-Loss Maintenance Intervention in Native Hawaiian- Serving Worksites

NCT01652989
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Weight Loss Maintenance
Interventions
Weight loss maintenance intervention face-to-face, Weight loss maintenance intervention delivered via DVD
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
8
States / cities
Honolulu, Hawaii • Kailua-Kona, Hawaii • Kaunakakai, Hawaii
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jun 10, 2026, 2:27 PM EDT
Active, not recruiting Phase 3 Interventional

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

NCT07011667
View directory record Official record
Conditions
Obesity
Interventions
CagriSema (Cagrilintide B and Semaglutide I), Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
46
States / cities
Costa Mesa, California • San Diego, California • Walnut Creek, California + 41 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increased Dietary Protein and Meal Frequency Reduces Total and Abdominal Body Fat During Weight Maintenance and Weight Loss

NCT01749449
View directory record Official record
Conditions
Obesity
Interventions
protein and meal frequency
Other
Lead sponsor
Skidmore College
Other
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2012 · Synced Jun 10, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Cancer, Obesity/Overweight and Insomnia Study

NCT03542604
View directory record Official record
Conditions
Breast Cancer, Overweight and Obesity, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Jun 10, 2026, 2:27 PM EDT
Not listed Not applicable Interventional

Using the Hunt Motivational Scale to Aid in Weight Loss and Weight Maintenance

NCT03530553
View directory record Official record
Conditions
Weight Loss
Interventions
Hunt Motivational Scale
Other
Lead sponsor
Penn Medicine Princeton Health
Other
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Plainsboro, New Jersey
Source: ClinicalTrials.gov public record
Updated May 20, 2018 · Synced Jun 10, 2026, 2:27 PM EDT