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ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:00 AM EDT

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Showing 1–24 of 584 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Interventions
iNO, Nitrogen
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 2 Minutes
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Conditions
Overweight, Obesity
Interventions
NNC0174-0833, Placebo (NNC0174-0833), Liraglutide 3.0 mg, Placebo (Liraglutide 3.0 mg)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
706 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
22
States / cities
Anaheim, California • Spring Valley, California • Crystal River, Florida + 19 more
Conditions
Obesity, Overweight, Chronic Weight Management
Interventions
aleniglipron or placebo
Drug
Lead sponsor
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Industry
Eligibility
18 Years to 79 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
10
States / cities
Glendale, California • Montclair, California • Valparaiso, Indiana + 7 more
Conditions
Weight Gain
Interventions
Fluid intake app, Survey
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Activity, Rheumatoid and Osteoarthritis, and Weight Management

NCT00365404
Conditions
Rheumatoid Arthritis, Osteoarthritis
Interventions
Diet and exercise promotion
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
465 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Conditions
Obesity
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
6 Years to 11 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Atlanta, Georgia • Oklahoma City, Oklahoma • Houston, Texas
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Weight Watchers modified program, Standard Care group
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
563 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
15
States / cities
Birmingham, Alabama • La Jolla, California • Augusta, Georgia + 11 more
Completed Phase 4 Interventional Accepts healthy volunteers

Weight-Based Torsemide Dosing in Subjects With Heart Failure

NCT03187509
Conditions
Heart Failure
Interventions
Torsemide, Standard Outpatient Heart Failure Management
Drug · Other
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
18 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Craving and Lifestyle Management Through Mindfulness Study

NCT01250509
Conditions
Obesity
Interventions
Craving and Lifestyle Management through Mindfulness
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Accepts healthy volunteers Results available

Antecedents of Obesity: Fetal Measures of Adiposity

NCT00715754
Conditions
Obesity
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
24 Hours to 72 Hours
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Obesity
Interventions
Multi-Modal Education (MME), Traditional Education (TE)
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
3,199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
8
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Iowa City, Iowa + 5 more
Conditions
Healthy Participants, Obesity
Interventions
AZD1043, Placebo
Drug · Other
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Glendale, California • Brooklyn, Maryland
Conditions
Obesity, Childhood
Interventions
Intensive Behavioral Program, Semaglutide and Behavioral Program
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Obesity, Diet Therapy, Weight Loss
Interventions
behavior modification for weight loss
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Sepsis, Septicemia, Sepsis Syndrome, Shock, Septic, Community Acquired Pneumonia
Interventions
Not listed
Lead sponsor
National Center for Genome Resources
Other
Eligibility
6 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
3
States / cities
Detroit, Michigan • Durham, North Carolina
Completed Phase 3 Interventional Results available

Individualized Obesity Pharmacotherapy

NCT03374956
Conditions
Obesity
Interventions
Phentermine-Topiramate, Liraglutide, Naltrexone/bupropion, Phentermine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Using Signos mHealth Platform in Adults for Weight Management

NCT06214221
Conditions
Overweight and Obesity, Metabolic Syndrome, Weight Loss
Interventions
Signos System, Standard Lifestyle Education
Device · Other
Lead sponsor
Signos Inc
Industry
Eligibility
22 Years and older
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
5
States / cities
Phoenix, Arizona • Walnut Creek, California • North Miami, Florida + 2 more
Conditions
Osteoarthritis
Interventions
Lifestyle Behavioral Weight Management Program, Pain-Coping Skills Training, Standard Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Weight Loss, Lifestyle Factors
Interventions
Wrist activity tracker and scale, Nutritional Coaching group sessions
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Enrolling by invitation Not applicable Interventional

ESG in Obese Adolescents

NCT06914765
Conditions
Obese Adolescents, Obesity, Morbid, Obesity/Therapy
Interventions
Endoscopic Sleeve Gastroplasty (ESG) Procedure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

Rural Engagement in Primary Care for Optimizing Weight Reduction

NCT02456636
Conditions
Obesity
Interventions
Fee-for-Service Model (FFS, In clinic individual visits), Patient Centered Medical Home (PCMH, In clinic group visits), Disease Management (DM, Phone group visits)
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 75 Years
Enrollment
1,432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Chronic Plaque Psoriasis
Interventions
alefacept
Drug
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
11
States / cities
Hot Springs, Arkansas • Fridley, Minnesota • Omaha, Nebraska + 8 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Efficacy of an Avocado Dietary Supplement

NCT07354308
Conditions
Overweight, Metabolic Health, Insulin Resistance
Interventions
Metavo Supplement, Placebo
Dietary Supplement
Lead sponsor
SP Nutraceuticals Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimal Digital Weight Loss Treatment for Rural Individuals

NCT06105957
Conditions
Overweight and Obesity
Interventions
Core, Facilitated Weekly Group Sessions, Counselor Crafted Feedback, Individual Coaching Calls, Pre-Scripted Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
616 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina