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ClinicalTrials.gov public records Last synced Oct 27, 2026, 11:27 AM EDT

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Showing 1033–1056 of 2,406 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Benefit Clear all
Withdrawn Not applicable Interventional

SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT

NCT03812341
View directory record Official record
Conditions
CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT
Interventions
Experimental
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
88 Years to 88 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Phase 2 Interventional Results available

MEDI4736 and Tremelimumab in Treating Patients With Metastatic HER2 Negative Breast Cancer

NCT02536794
View directory record Official record
Conditions
Estrogen Receptor Negative, Estrogen Receptor Positive, HER2/Neu Negative, Recurrent Breast Carcinoma, Stage IV Breast Cancer
Interventions
Anti-B7H1 Monoclonal Antibody MEDI4736, Laboratory Biomarker Analysis, Pharmacological Study, Tremelimumab
Biological · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Chicago, Illinois • Lake Forest, Illinois
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prevention of Obesity in Military Communities - Fit4Duty

NCT02679937
View directory record Official record
Conditions
Obesity, Overweight, Adiposity
Interventions
Fit4Duty, Nutrition Education
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
Bethesda, Maryland • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Phase 3 Interventional Results available

A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma

NCT03434379
View directory record Official record
Conditions
Carcinoma, Hepatocellular
Interventions
Atezolizumab, Bevacizumab, Sorafenib
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
558 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
21
States / cities
Phoenix, Arizona • Duarte, California • La Jolla, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 27, 2026, 11:27 AM EDT
Terminated Phase 4 Interventional Results available

Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures

NCT03361137
View directory record Official record
Conditions
Hemophilia A
Interventions
Emicizumab
Drug
Lead sponsor
Genentech, Inc.
Industry
Eligibility
Not listed
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
8
States / cities
Los Angeles, California • Palo Alto, California • Gainesville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 27, 2026, 11:27 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Iadademstat + SBRT With Atezo in ES-SCLC

NCT07113691
View directory record Official record
Conditions
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Interventions
Iadademstat, Atezolizumab, SBRT
Drug · Radiation
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Active, not recruiting Phase 3 Interventional

A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)

NCT03148418
View directory record Official record
Conditions
Cancer
Interventions
Atezolizumab, Bevacizumab
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
Not listed
Enrollment
382 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
44
States / cities
Scottsdale, Arizona • Los Angeles, California • San Marcos, California + 36 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Early Phase 1 Interventional

A Single Dose FMT Infusion as an Adjunct to Keytruda for Metastatic Mesothelioma

NCT04056026
View directory record Official record
Conditions
Mesothelioma
Interventions
Fecal Microbiota Transplant
Biological
Lead sponsor
ProgenaBiome
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Oct 27, 2026, 11:27 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)

NCT04913220
View directory record Official record
Conditions
Malignant Melanoma, Squamous Cell Carcinoma of Skin
Interventions
THOR-707, Cemiplimab
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Comparing Smartphone Technology and a Memory Strategy on Improving Prospective Memory in Alzheimer's Disease

NCT03384043
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Impairment, Mild, Dementia, Mild
Interventions
Smartphone Personal Assistant, Implementation Intention
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
Not listed
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 27, 2026, 11:27 AM EDT
Active, not recruiting Not applicable Interventional Results available

A Multi-modal, Physician-centered Intervention to Improve Guideline-concordant Prostate Cancer Imaging

NCT03445559
View directory record Official record
Conditions
Prostate Cancer
Interventions
Clinical Order Check, Academic Detailing, Audit and Feedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
11
States / cities
Palo Alto, California • West Los Angeles, California • West Haven, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Phase 2 Interventional Results available

Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma

NCT00121225
View directory record Official record
Conditions
Ciliary Body and Choroid Melanoma, Medium/Large Size, Extraocular Extension Melanoma, Iris Melanoma, Uveal Melanoma, Recurrent Intraocular Melanoma, Recurrent Melanoma, Stage IV Melanoma
Interventions
vorinostat
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Rockledge, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Oct 27, 2026, 11:27 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Leveraging Video Vignettes and Social Media to Promote Safe Firearm Storage Among Veterans

NCT07756697
View directory record Official record
Conditions
Lethal Means Safety
Interventions
WAV videos, VA News videos, VA LMS brochure
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
654 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Recruiting Phase 1 Interventional

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

NCT06884618
View directory record Official record
Conditions
Neoplasms
Interventions
RO7673396
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
6
States / cities
Duarte, California • Aurora, Colorado • New Haven, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

NCT03803423
View directory record Official record
Conditions
End Stage Renal Disease, End Stage Liver Disease
Interventions
The Donor App
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
6
States / cities
San Diego, California • New Haven, Connecticut • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Phase 2 Interventional Results available

SU011248 In The Treatment Of Patients With Bevacizumab (Avastin)-Refractory Metastatic Renal Cell Carcinoma

NCT00089648
View directory record Official record
Conditions
Carcinoma, Renal Cell
Interventions
Sunitinib
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
11
States / cities
Duarte, California • Pasadena, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2010 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional

The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services

NCT04295876
View directory record Official record
Conditions
HIV/AIDS
Interventions
The BRIDGES Project Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Depression Management at the Workplace

NCT01013220
View directory record Official record
Conditions
Depression
Interventions
Depression Product Detailing, Depression HEDIS detailing
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
293 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 27, 2026, 11:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders

NCT01274026
View directory record Official record
Conditions
Phenylketonuria, Behavior and Behavior Mechanisms, PAH Gene Expression
Interventions
sapropterin dihydrochloride
Drug
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
2 Years to 21 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes

NCT06518798
View directory record Official record
Conditions
Prediabetes, Prediabetic State
Interventions
Fasting Mimicking Diet
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Phase 1 Interventional

Preserving Function Among Disability Applicants

NCT00530985
View directory record Official record
Conditions
Disability
Interventions
Benefits Counseling, VA Orientation
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2009 · Synced Oct 27, 2026, 11:27 AM EDT
Recruiting Not applicable Interventional

Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)

NCT06580847
View directory record Official record
Conditions
Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
Interventions
Group Singing, Audiobook Club
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
60 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Informational Meetings for Planning and Coordinating Treatment

NCT04330833
View directory record Official record
Conditions
End of Life, Communication, Cancer Metastatic
Interventions
Novel Communication Intervention, Enhanced Usual Care Parent Education
Other
Lead sponsor
Indiana University
Other
Eligibility
1 Month to 17 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
7
States / cities
Aurora, Colorado • Wilmington, Delaware • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 27, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Life STORRIED Study

NCT03134092
View directory record Official record
Conditions
Opioid Dependence, Communication, Risk Behavior, Narrative Medicine
Interventions
Probabilistic Risk Communication Tool (PRT), Narrative Enhanced Risk Tool (NERT)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
1,302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
4
States / cities
Birmingham, Alabama • Rochester, Minnesota • Manhasset, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 27, 2026, 11:27 AM EDT