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Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
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Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
Use of OP-1 Putty in Uninstrumented posterolateral fusion
Device
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 81 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
5
States / cities
New Haven, Connecticut • Chicago, Illinois • Royal Oak, Michigan + 2 more
Conditions
Degenerative Disc Disease
Interventions
TLIF with a PEEK Spacer System and XIA Spinal System
Device
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
10
States / cities
Los Angeles, California • San Diego, California • Durango, Colorado + 7 more
Conditions
Osteoarthritis of the Knee
Interventions
Bone morphogenetic protein 7, Placebo
Drug
Lead sponsor
Stryker Biotech
Industry
Eligibility
40 Years and older
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
25
States / cities
Glendale, Arizona • Tucson, Arizona • Palo Alto, California + 20 more
Conditions
Healthy Volunteers, Alzheimer Disease
Interventions
ALZT-OP1 (cromolyn and ibuprofen) ALZT-OP1a (cromolyn) and ALZT-OP1b (ibuprofen)
Drug
Lead sponsor
AZTherapies, Inc.
Industry
Eligibility
55 Years to 79 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami Lakes, Florida
Completed Not applicable Interventional

OP-1 Putty for Posterolateral Fusions

NCT00677950
Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
Spinal fusion
Procedure
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
21
States / cities
Santa Monica, California • Stanford, California • Denver, Colorado + 18 more
Conditions
Tibial Nonunions
Interventions
Surgical implantation of OP-1 device or autograft bone graft material
Device
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 1999
U.S. locations
18
States / cities
Mesa, Arizona • Modesto, California • San Diego, California + 15 more
Conditions
Alzheimer's Disease
Interventions
ALZT-OP1a, ALZT-OP1b, Placebo ALZT-OP1a, Placebo ALZT-OP1b
Drug · Other
Lead sponsor
AZTherapies, Inc.
Industry
Eligibility
55 Years to 79 Years
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
69
States / cities
Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 56 more
Conditions
Osteoarthritis of the Knee
Interventions
Bone morphogenetic protein 7
Drug
Lead sponsor
Stryker Biotech
Industry
Eligibility
40 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Gainesville, Florida • Boston, Massachusetts
Conditions
Healthy Volunteers
Interventions
ALZT-OP1a, ALZT-OP1b, Dry Powder Inhaler
Drug · Device
Lead sponsor
AZTherapies, Inc.
Industry
Eligibility
55 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Miami Lakes, Florida
Conditions
Malocclusion
Interventions
Fixed Appliance Orthodontic Treatment, OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona
Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
Not listed
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
19
States / cities
Santa Monica, California • Stanford, California • Denver, Colorado + 16 more
Conditions
Osteoarthritis of the Knee
Interventions
Intra-articular Injection of OP-1 to affected knee
Drug
Lead sponsor
Stryker Biotech
Industry
Eligibility
40 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
3
States / cities
Boston, Massachusetts • Chapel Hill, North Carolina
Conditions
Opioid Use Disorder
Interventions
Brenipatide, Placebo, Buprenorphine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
38
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Fountain Valley, California + 30 more