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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:28 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 423 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Botulinum toxin(Botox) Clear all

Conditions: Glabellar Frown Lines
Interventions: Botulinum Toxin A, Placebo, Botulinum Toxin A - Open Label; Drug
Lead sponsor: Croma-Pharma GmbH; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 7
States / cities: Encinitas, California • Aventura, Florida • Sarasota, Florida + 4 more

Conditions: Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
Interventions: Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask; Drug · Other
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Chronic Migraine
Interventions: Xeomin, Placebo; Drug
Lead sponsor: Merz Therapeutics GmbH; Industry
Eligibility: 18 Years and older
Enrollment: 808 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 48
States / cities: Chandler, Arizona • Phoenix, Arizona • Little Rock, Arkansas + 42 more

Conditions: Urinary Bladder, Overactive, Pelvic Organ Prolapse
Interventions: OnabotulinumtoxinA 100 UNT, Injectable saline; Drug · Other
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Facial Fine Lines
Interventions: Botox, Placebo; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 172 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 5
States / cities: Miami, Florida • New York, New York • Nashville, Tennessee + 2 more

Conditions: Acne Vulgaris
Interventions: ANT-1207, Vehicle; Biological
Lead sponsor: Anterios Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 15
States / cities: Birmingham, Alabama • Miami, Florida • West Palm Beach, Florida + 12 more

Conditions: Moderate to Severe Glabellar Frown Lines
Interventions: IncobotulinumtoxinA (Xeomin) (20 Units), Placebo; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years and older
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 5
States / cities: Los Angeles, California • Meatrie, Louisiana • Chestnut Hill, Massachusetts + 2 more

Conditions: Pediatrics, Muscle Spasticity, Cerebral Palsy
Interventions: Botulinum Toxin Type A; Biological
Lead sponsor: Allergan; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 370 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 26
States / cities: Pasadena, California • Pomona, California • San Diego, California + 21 more

Conditions: Myofascial Pelvic Pain
Interventions: Intervention-Botulinum Toxin Type A, placebo; Drug
Lead sponsor: Boston Urogynecology Associates; Other
Eligibility: 18 Years and older · Female only
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Healthy
Interventions: onabotulinumtoxinA; Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 30 Years to 40 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Irvine, California

Conditions: Achalasia
Interventions: Botulinum toxin type A, Endoscope balloon dilator, Patient reported outcomes, Barium esophagram; Drug · Device · Other + 1 more
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Lateral Canthal Lines
Interventions: DaxibotulinumtoxinA for injection; Biological
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 4
States / cities: Sacramento, California • Sarasota, Florida • Itasca, Illinois + 1 more

Conditions: Functional Popliteal Artery Entrapment Syndrome, Popliteal Artery Entrapment Syndrome
Interventions: Dysport; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 50 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Benign Prostatic Hyperplasia
Interventions: Botulinum Toxin Type A, Placebo (saline); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 45 Years to 70 Years · Male only
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Neuropathic Pain
Interventions: onabotulinum toxin A; Drug
Lead sponsor: Isabel Moreno Hay; Other
Eligibility: 18 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Depressive Disorder, Major
Interventions: onabotulinumtoxinA, Normal Saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 35
States / cities: Little Rock, Alaska • Bellflower, California • Cerritos, California + 29 more

Conditions: Carpal Tunnel Syndrome
Interventions: Botulinum Toxin Type A, Placebo; Drug
Lead sponsor: Benjamin Sucher; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Parkinson Disease
Interventions: Botulinum Toxin Type A, Placebo; Biological
Lead sponsor: University of Cincinnati; Other
Eligibility: 35 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Upper Limb Spasticity (Altered Skeletal Muscle Performance) in Children
Interventions: Botulinum toxin type A; Biological
Lead sponsor: Ipsen; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 12
States / cities: Aurora, Colorado • Washington D.C., District of Columbia • New Orleans, Louisiana + 9 more

Conditions: Diabetes Mellitus, Peripheral Neuropathy, Plantar Ulcers
Interventions: Botulinum Toxin, Saline; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: Not listed
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Esophageal Carcinoma
Interventions: Botulinum Toxin Type A, Esophagectomy, Quality-of-Life Assessment; Biological · Procedure · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Overactive Bladder
Interventions: Botox; Drug
Lead sponsor: Urological Sciences Research Foundation; Other
Eligibility: 40 Years to 90 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 1
States / cities: Culver City, California

Conditions: Chronic Low Back Pain
Interventions: Botulinum Toxin A / Placebo, Botulinum Toxin A / Botulinum Toxin A, Placebo / Botulinum Toxin A, Placebo / Placebo; Drug
Lead sponsor: Walter Reed Army Medical Center; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Glabellar Rhytides, Frown Lines Between the Eyebrows
Interventions: Mentor Purified Toxin Botulinum Toxin Type A, Preservative-free Saline; Drug
Lead sponsor: Mentor Worldwide, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 699 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Santa Barbara, California

Search by objective public record fields.

Botulinum Toxin Treatment of Glabellar Lines: Efficacy and Safety Study II

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

BOTOX® at the Time of Prolapse Surgery for OAB

Intradermal (ID) BOTOX in the Treatment of Facial Fine Lines

Clinical Trial To Evaluate ANT-1207 In Subjects With Acne

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines No. 2

BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity

Botulinum Toxin Type A Versus Saline Trigger Point Injections for Myofascial Pelvic Pain

Functional Effects of Botox on the Brain Using MRS and fMRI

Botox or Botox With Esophageal Dilation in Patients With Achalasia

Efficacy and Safety of Increasing Doses of DaxibotulinumtoxinA for Injection (DAXI for Injection) in the Treatment of Moderate or Severe Lateral Canthal Lines

Botulinum Toxin Injection for Functional Popliteal Artery Entrapment Syndrome

A Study Evaluating the Effect of Botulinum Toxin Type A on Semen Quality in Patients With Benign Prostatic Hyperplasia

Intraoral Administration of Botox in Patients With Dentoalveolar Neuropathic Pain

OnabotulinumtoxinA as Treatment for Major Depressive Disorder in Adult Females

BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome

Botulinum Toxin Type A (Botox) in the Management of Levodopa-Induced Peak-Dose Dyskinesias in Parkinson's Disease

Efficacy And Safety Of Dysport In The Treatment Of Upper Limb Spasticity In Children

Botulinum Toxin Effects on Plantar Ulcer Recurrence

Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

This is a Prospective, Randomized, Double-Blind Study Comparing Intravesical Injection of Botox® to Placebo.

Botulinum Toxin A for the Treatment of Chronic Lumbar Back Pain

Safety and Efficacy Study of Repeat Treatment With PurTox® Botulinum Toxin Type A for Frown Lines Between the Eyebrows