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ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:38 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: CRT device implant Clear all

Conditions: Heart Failure; With Decompensation
Interventions: Medtronic ICDs, CRT-Ds, and CRT-Ps; Device
Lead sponsor: Charles Porter, MD; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 3
States / cities: Des Moines, Iowa • Columbus, Ohio • Fairfield, Ohio

Conditions: Bradycardia
Interventions: Evaluation Group, Control Group (Historical); Other
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 257 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 11
States / cities: Palo Alto, California • Hartford, Connecticut • Daytona Beach, Florida + 8 more

Conditions: Shock
Interventions: ICD/ CRT-D; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,670 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Heart Failure
Interventions: Subcutaneous adipose tissue collection, Peripheral arterial tonometry (PAT); Procedure · Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Congestive Heart Failure, Cardiac Resynchronization Therapy
Interventions: Kronos LV-T, Lumax HF-T; Device
Lead sponsor: Biotronik, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 12
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Wilmington, Delaware + 9 more

Conditions: Heart Failure, ICD, Chronotropic Incompetence
Interventions: CLS Mode on Biotronik CRT-D, Accelerometer Mode on Biotronik CRT-D; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 99 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 684 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 34
States / cities: Huntsville, Alabama • Anchorage, Alaska • Redwood City, California + 31 more

Conditions: Congestive Heart Failure
Interventions: Paradym CRT + Physiological Diagnosis (PhD); Device
Lead sponsor: ELA Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Heart Failure, Ventricular Arrhythmias
Interventions: CRT device implant; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: New York, New York • Pittsburgh, Pennsylvania

Conditions: Heart Failure
Interventions: HeartNet Ventricular Support System, Optimal Medical/Device Therapy; Device · Drug
Lead sponsor: Paracor Medical, Inc; Industry
Eligibility: 18 Years to 74 Years
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 29
States / cities: Birmingham, Alabama • Los Angeles, California • San Francisco, California + 26 more

Conditions: Heart Failure
Interventions: Echocardiogram/SonR; Other
Lead sponsor: Piedmont Healthcare; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tachyarrhythmias, Sudden Cardiac Death, Heart Failure
Interventions: SJ4 connector and RV high voltage SJ4 lead; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,701 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Cardiac Resynchronization Therapy, Heart Failure
Interventions: Primary epicardial placement of left ventricular lead, Transvenous placement of left ventricular lead; Procedure
Lead sponsor: St. Luke's-Roosevelt Hospital Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
Interventions: CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment; Device
Lead sponsor: XSpline S.p.A.; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 4
States / cities: Chicago, Illinois • Boston, Massachusetts • Durham, North Carolina

Conditions: Bradyarrhythmia, Heart Failure
Interventions: Data collection; Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 383 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 5
States / cities: Tucson, Arizona • Chicago, Illinois • New York, New York + 2 more

Conditions: Systolic Heart Failure, Atrial Fibrillation (Permanent)
Interventions: Atrioventricular junctional (AVJ) ablation, Cardiac resynchronization therapy - defibrillator; Procedure · Device
Lead sponsor: University of Rochester; Other
Eligibility: 21 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 21
States / cities: Little Rock, Arkansas • Pasadena, California • Atlanta, Georgia + 16 more

Conditions: Systolic Heart Failure, Heart Failure With Reduced Ejection Fraction, CRT Non-Response, Left Bundle Branch Area Pacing
Interventions: Left bundle branch area pacing, Cardiac MRI; Device · Diagnostic Test
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Heart Failure - NYHA II - IV
Interventions: CRT-D with a Quadripolar LV lead, CRT-D with INGEVITY+ pace/sense lead; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 43
States / cities: Huntsville, Alabama • Mobile, Alabama • Phoenix, Arizona + 37 more

Conditions: Heart Failure (NYHA Class III and Ambulatory IV)
Interventions: SonR automatic optimization feature turned ON ("AV+VV").; Device
Lead sponsor: MicroPort CRM; Industry
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Heart Failure, Cardiomyopathy, Cardiac Arrhythmia
Interventions: QLV interval measurement; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Heart Failure
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 221 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Failure
Interventions: Pacing Lead; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 19
States / cities: Anchorage, Alaska • Phoenix, Arizona • Long Beach, California + 16 more

Conditions: Cardiac Resynchronization Therapy, Heart Failure
Interventions: Postero-lateral, Antero-Lateral; Procedure
Lead sponsor: Sergio Thal, M.D.; Federal
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 2
States / cities: Tucson, Arizona • Lexington, Kentucky

Search by objective public record fields.

Dynamic Thoracic Impedance as a Marker for Heart Failure Decompensation

Sensor Optimization of Cardiac Resynchronization Therapy Response

BlueSync Field Evaluation

Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

TRIAGE-CRT Telemonitoring in Patients With CHF and Indication of CRT-D

Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device

Risk Stratification and Benefits With Cardiac Resynchronization Therapy (CRT)

Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial

Atrio-Ventricular (AV) Delay Optimization Using Echocardiography Versus the SonR Signal

SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibrillator Patients

Comparison of Epicardial Versus Conventional Lead Placement in Cardiac Resynchronization Therapy

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

Conduction System Pacing International Registry (CONSPIRE)

Junctional AV Ablation in CRT-D: JAVA-CRT

Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Continued Access Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D

Correlating QLV Interval to Left Ventricular (LV) Lead Position in Patients Receiving Cardiac Resynchronization Therapy.

Biomarkers to Predict CRT Response in Patients With HF (BIOCRT)

Attain Model 4196 Left Ventricular (LV) Lead

POsition of Leads in Advanced heaRt Failure: the POLAR Study