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Showing 25–48 of 159 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Hybrid Coronary Revascularization Trial

NCT03089398
Conditions
Coronary Artery Disease
Interventions
Hybrid Coronary Revascularization (isolated LIMA-LAD), Hybrid Coronary Revascularization (PCI), Percutaneous Coronary Intervention
Procedure · Device
Lead sponsor
Emilia Bagiella
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
39
States / cities
Long Beach, California • Los Angeles, California • Stanford, California + 31 more
Conditions
Coronary Artery Disease (CAD)
Interventions
XC001, A195/placebo
Drug
Lead sponsor
XyloCor Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery

NCT05853250
Conditions
Coronary Artery Diseases, Valvular Heart Diseases
Interventions
Reiki/manual therapy
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Completed No phase listed Observational

Platelet Reactivity After CABG

NCT01793597
Conditions
Acute Coronary Syndrome
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
3D Transesophageal and Transthoracic Echocardiogram
Interventions
transesophageal echocardiography (TEE), thermodilution, transthoracic echocardiography (TTE)
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Systemic Inflammatory Response Syndrome, Acute Kidney Injury
Interventions
coronary artery bypass grafting using cardiopulmonary bypass
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Bloodloss, Surgical Procedures, Operative
Interventions
ecallantide, placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years to 85 Years
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
21
States / cities
Birmingham, Alabama • Montgomery, Alabama • Aurora, Colorado + 14 more
Conditions
Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus, Heart Diseases
Interventions
Coronary Artery Bypass Graft, Percutaneous Coronary Intervention
Procedure · Device
Lead sponsor
Valentin Fuster
Other
Eligibility
18 Years and older
Enrollment
1,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Trauma, Vascular System Injury
Interventions
Acellular Tissue Engineered Vessel (ATEV)
Biological
Lead sponsor
Humacyte, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
27
States / cities
La Jolla, California • Los Angeles, California • Orange, California + 18 more
Conditions
Coronary Artery Disease
Interventions
Clopidogrel withdraw prior to CABG
Other
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Acute Kidney Injury
Interventions
Digoxin Antibodies Fab Fragments, Placebo, Baseline EO > 360 pM, EO < 360 pM
Drug · Other · Diagnostic Test
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Conditions
Bleeding Reduction
Interventions
Acute Normovolemic Hemodilution
Procedure
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 85 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Falls Church, Virginia
Conditions
Coronary Arteriosclerosis, Coronary Artery Bypass Graft, Myocardial Revascularization
Interventions
Autologous stem cell therapy, CABG, CMRI
Procedure · Radiation
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Ischemic Heart Disease
Interventions
Coronary artery bypass - on-pump, Coronary artery bypass - off-pump
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
2,203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
17
States / cities
Palo Alto, California • San Francisco, California • Sepulveda, California + 14 more
Conditions
Coronary Artery Disease
Interventions
Coronary artery bypass grafting (CABG), Valve replacement
Procedure
Lead sponsor
University of Miami
Other
Eligibility
50 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Miami, Florida
Conditions
Coronary Artery Disease, Cognitive Impairment, Heart Failure
Interventions
Guideline-directed medical therapy (GDMT), Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI).
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
New York, New York
Conditions
Pain
Interventions
Parecoxib Sodium/Valdecoxib, Placebo/Valdecoxib, Placebo/Placebo
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,671 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
84
States / cities
Fairhope, Alabama • Mobile, Alabama • Tucson, Arizona + 61 more
Conditions
Heart Failure, LVAD
Interventions
Off-Pump, On-Pump
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Post Operative Atrial Fibrillation
Interventions
CardiaMend with the Addition of Amiodarone
Combination Product
Lead sponsor
WakeMed Health and Hospitals
Other
Eligibility
20 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Raleigh, North Carolina
Conditions
Coronary Artery Bypass Grafting, Mitral Valve Surgery, Low Cardiac Output Syndrome
Interventions
Levosimendan, Placebo
Drug
Lead sponsor
Tenax Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
882 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
49
States / cities
Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more
Conditions
Diabetes
Interventions
Regular insulin (intensive treatment), Regular Insulin (conventional treatment)
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Coronary Disease
Interventions
INS50589 Intravenous Infusion
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Timeline
Started 2006
U.S. locations
27
States / cities
Birmingham, Alabama • San Diego, California • Springfield, Illinois + 13 more
Conditions
Coronary Artery Disease
Interventions
MICS CABG, Conventional CABG
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • La Crosse, Wisconsin
Conditions
Surgery, Pneumonia, Surgical Site Infection
Interventions
Continuous Sternal Block, Opioid based analgesia
Device · Drug
Lead sponsor
Halyard Health
Industry
Eligibility
18 Years and older
Enrollment
647 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
8
States / cities
Birmingham, Alabama • Newark, Delaware • Lexington, Kentucky + 5 more