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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:50 PM EDT

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Showing 673–696 of 4,838 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Depression Clear all
Completed Not applicable Interventional Results available

HOPE Pilot for Veterans With Complex Diabetes

NCT01274715
View directory record Official record
Conditions
Diabetes, Depression
Interventions
Behavioral Health Coaching
Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Oct 23, 2026, 2:50 PM EDT
Withdrawn Not applicable Interventional

Trauma Informed Care for Newly Resettled Refugees

NCT03288935
View directory record Official record
Conditions
Mental Stress, Emotional Stress
Interventions
TICM, TICO
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 23, 2026, 2:50 PM EDT
Terminated Phase 4 Interventional Results available

Pioglitazone for the Treatment of Bipolar Depression

NCT01717040
View directory record Official record
Conditions
Bipolar Disorder, Insulin Resistance
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Oct 23, 2026, 2:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Timing of Opioid Administration and Postoperative Respiratory Depression.

NCT07227389
View directory record Official record
Conditions
Respiratory Complications, Opioid Induced Respiratory Depression, Postoperative Respiratory Complications
Interventions
Respiratory volume monitoring
Diagnostic Test
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Phase 2Phase 3 Interventional

A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder

NCT04832425
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
PRAX-114, Placebo
Drug
Lead sponsor
Praxis Precision Medicines
Industry
Eligibility
18 Years to 65 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
30
States / cities
Phoenix, Arizona • Garden Grove, California • Lafayette, California + 27 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Phase 1 Interventional Results available

Modeling Mood Course to Detect Markers for Effective Adaptive Interventions- Aim 3

NCT04098497
View directory record Official record
Conditions
Bipolar Disorder, Psychosocial Intervention
Interventions
Mobile intervention
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 23, 2026, 2:50 PM EDT
Recruiting Not applicable Interventional

Safety and Feasibility of DBS for Bipolar Depression

NCT07745374
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar Depression
Interventions
Medtronic Percept PC DBS system
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
22 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Pilot Trial of Phototherapy for Acute Depression in Hospitalized Cystic Fibrosis Patients

NCT01822197
View directory record Official record
Conditions
Depression, Cystic Fibrosis
Interventions
Phototherapy
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

AI-Based Fidelity Feedback to Enhance CBT

NCT05340738
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Therapy
Interventions
LyssnCBT
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain

NCT00678717
View directory record Official record
Conditions
Chronic Pain
Interventions
Autonomic Evaluation
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 16, 2018 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder

NCT02494050
View directory record Official record
Conditions
Depression, Bipolar Disorder, Anhedonia
Interventions
Behavioral Activation-Full, Behavioral Activation-Short, Bipolar Disorder Collaborative Care
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Pharmacogenomic Testing in Primary Care

NCT03270891
View directory record Official record
Conditions
Antidepressants Causing Adverse Effects in Therapeutic Use
Interventions
PGx test
Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Oct 23, 2026, 2:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Can Oxytocin Level Predict Postpartum Depression?

NCT02020148
View directory record Official record
Conditions
Postpartum Depression
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 23, 2026, 2:50 PM EDT
Recruiting Phase 2 Interventional

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

NCT06696755
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar II Disorder
Interventions
Icalcaprant, Placebo for Icalcaprant
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years to 65 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
33
States / cities
Huntsville, Alabama • Chandler, Arizona • Tucson, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Not listed Not applicable Interventional

Internet-Based Interventions for Bipolar Disorder

NCT02106078
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Moderated Discussion Board, Psychoeducation, Interactive Psychosocial Tools
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
21 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2015 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Phase 4 Interventional

Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder

NCT00227968
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Interpersonal Social Rhythm Therapy (IPSRT), Clinical Status and Symptom Response Therapy (CSSRT)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2002
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2013 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Sleep Therapy for Insomnia and Depression

NCT02943278
View directory record Official record
Conditions
Depression, Insomnia
Interventions
Intensive Sleep Retraining, Sleep Hygiene
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Outreach and Treatment for Depression in the Labor Force

NCT00057590
View directory record Official record
Conditions
Depression
Interventions
Care manager outreach and monitoring
Behavioral
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years and older
Enrollment
590 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional

A Culturally Sensitive Social Support Intervention

NCT02946697
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms
Interventions
Social support intervention
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 23, 2026, 2:50 PM EDT
Recruiting Not applicable Interventional

Vanderbilt Integrated Community TMS for Opioid Recovery

NCT07457489
View directory record Official record
Conditions
Opiod Use Disorder
Interventions
Device: Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Brentwood, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Not yet recruiting Not applicable Interventional

Digitally Enhanced Cognitive-Behavioral Therapy

NCT07569991
View directory record Official record
Conditions
Depression in Adolescence, Obesity & Overweight, Cognitive-behavioral Therapy, Mobile Health Technology (mHealth), Health Behavior
Interventions
Cognitive-behavioral therapy (CBT), Digital app
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia

NCT00928720
View directory record Official record
Conditions
Fibromyalgia
Interventions
CES device, sham device
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 23, 2026, 2:50 PM EDT
Enrolling by invitation Not applicable Interventional

Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth

NCT06273982
View directory record Official record
Conditions
Depression, Anxiety
Interventions
STEP-UP (transdiagnostic behavioral therapy for pediatric anxiety and depression), ARC (assisted referral to community care)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
8 Years to 16 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 23, 2026, 2:50 PM EDT
Not listed Phase 2 Interventional

Healthy Outcomes of Pregnancy Education

NCT00381823
View directory record Official record
Conditions
Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2006 · Synced Oct 23, 2026, 2:50 PM EDT