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ClinicalTrials.gov public records Last synced Sep 15, 2026, 11:26 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Dual chamber pacemaker Clear all
Completed No phase listed Observational

Exercise in Chronically Paced Children

NCT00374608
View directory record Official record
Conditions
Congenital Diseases, Complete Heart Block, Pacemaker
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
10 Years to 21 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Sep 15, 2026, 11:26 AM EDT
Completed No phase listed Observational Results available

Imaging Study of Lead Implant for His Bundle Pacing

NCT03294317
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial
Interventions
His bundle pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Indianapolis, Indiana • Wilkes-Barre, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Not applicable Interventional Results available

Advisa MRI Clinical Study

NCT01110915
View directory record Official record
Conditions
Magnetic Resonance Imaging, Cardiac Pacemaker, Artificial
Interventions
Medtronic Advisa MRI Implantable Pulse Generator (IPG), Medtronic CapSureFix MRI™ active fixation MRI lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Salinas, California • Orlando, Florida • West Des Moines, Iowa + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 4 Interventional

Evaluation of the SafeR Mode in Patients With a Dual Chamber Pacemaker Indication

NCT00562107
View directory record Official record
Conditions
Assess the Benefits From the AAISafeR/SafeR Algorithm of Symphony 2550 or REPLYTM DR in a Wide Range of Pacemaker Patients.
Interventions
Symphony DR 2550 and REPLY DR cardiac pacemakers
Device
Lead sponsor
LivaNova
Industry
Eligibility
Not listed
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 28, 2014 · Synced Sep 15, 2026, 11:26 AM EDT
Recruiting No phase listed Observational

His Bundle Pacing in Bradycardia and Heart Failure

NCT03008291
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation
Procedure
Lead sponsor
Yong-Mei Cha
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 4 Interventional

Reduce Ventricular Pacing in Dual Chamber Implantable Cardioverter Defibrillators Using AutoIntrinsic Conduction Search Study

NCT00187239
View directory record Official record
Conditions
Arrhythmia
Interventions
Autointrinsic Conduction Search Algorithm
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Not applicable Interventional Results available

PREFER (Pacemaker Remote Follow-Up Evaluation and Review)

NCT00294645
View directory record Official record
Conditions
Bradycardia, Arrhythmia
Interventions
Transtelephonic monitoring (TTM), Medtronic CareLink® Network
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
980 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
45
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Washington D.C., District of Columbia + 42 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2010 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Not applicable Interventional Results available

Aveir DR i2i Study

NCT05252702
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial, Cardiac Rhythm Disorder, Bradycardia
Interventions
Aveir DR Leadless Pacemaker System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
54
States / cities
Scottsdale, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 44 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 15, 2026, 11:26 AM EDT
Active, not recruiting No phase listed Observational

Longitudinal Coverage With Evidence Development Study on Micra AV Leadless Pacemakers (Micra AV CED)

NCT04235491
View directory record Official record
Conditions
Bradycardia
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
37,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 15, 2026, 11:26 AM EDT
Terminated Not applicable Interventional Results available

MIRACLE EF Clinical Study

NCT01735916
View directory record Official record
Conditions
Congestive Heart Failure, Left Bundle Branch Block, Systolic Heart Failure
Interventions
CRT-P Implant, CRT-P OFF
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
69
States / cities
Concord, California • La Jolla, California • Los Angeles, California + 62 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 4 Interventional

Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications

NCT00729703
View directory record Official record
Conditions
Tachycardia
Interventions
OVATIO DR 6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
5
States / cities
Atlanta, Georgia • Decatur, Georgia • Mandeville, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 3 Interventional Results available

Effects of Exenatide Long-Acting Release on Glucose Control and Safety in Subjects With Type 2 Diabetes Mellitus(DURATION - 1)

NCT00308139
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
exenatide, long acting release, exenatide
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
16 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
24
States / cities
Encino, California • La Jolla, California • San Diego, California + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Not applicable Interventional

Pacing in First-degree AV-block

NCT01985802
View directory record Official record
Conditions
First-degree AV-block, Pacing
Interventions
Pacing
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Sep 15, 2026, 11:26 AM EDT
Completed No phase listed Observational

Sensing Atrial High Rate Episodes With Implantable Cardioverter-Defibrillators Trial (The SENSE Trial)

NCT02186704
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ICD with DX system
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
8
States / cities
Birmingham, Alabama • Boston, Massachusetts • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Effect of Ranolazine and Dronedarone When Given Alone and in Combination in Patients With Paroxysmal Atrial Fibrillation

NCT01522651
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Ranolazine, Dronedarone, Ranolazine placebo, Dronedarone placebo
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
15
States / cities
Beverly Hills, California • Newport Beach, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 4 Interventional Results available

The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock

NCT00787800
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation, Supraventricular Tachycardia
Interventions
Dual Chamber ICD, Single Chamber ICD
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Phase 4 Interventional

Syncope: Pacing or Recording in the Later Years

NCT01423994
View directory record Official record
Conditions
Syncope, Heart Block, Conduction Disorder of the Heart
Interventions
pacemaker, implantable loop recorder
Procedure
Lead sponsor
Canadian Institutes of Health Research (CIHR)
Government
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Sep 15, 2026, 11:26 AM EDT
Recruiting No phase listed Observational

AVEIR DR Coverage With Evidence Development (CED) Study

NCT05932602
View directory record Official record
Conditions
Cardiac Pacemaker, Arrythmia, Bradycardia
Interventions
Aveir DR Leadless Pacemaker System, Dual Chamber Transvenous Pacemaker
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,812 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Not applicable Interventional

The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy

NCT03549468
View directory record Official record
Conditions
Ischemic Cardiomyopathy
Interventions
Low level tragus stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 15, 2026, 11:26 AM EDT
Withdrawn Phase 1 Interventional

Exenatide For Reducing the Reinforcing Effects of Cocaine

NCT06252623
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Exenatide, Placebo
Drug
Lead sponsor
Christopher D. Verrico
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 15, 2026, 11:26 AM EDT
Completed Not applicable Interventional

Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)

NCT06601322
View directory record Official record
Conditions
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Interventions
Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 15, 2026, 11:26 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Bioequivalence Study to Compare Two Injection Devices for BMN 111 in Healthy Participants

NCT05813314
View directory record Official record
Conditions
Achondroplasia
Interventions
BMN 111 administration via Injector Pen, BMN 111 administration via vial and syringe
Combination Product · Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 15, 2026, 11:26 AM EDT
Terminated Phase 4 Interventional Results available

Right Ventricular (RV) Pacing in Early Post-operative Continuous Flow Left Ventricular Assist Device (LVAD)

NCT01446796
View directory record Official record
Conditions
Heart Failure
Interventions
Implantable Cardioverter-Defibrillator (subject's pre-existing ICD)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Sep 15, 2026, 11:26 AM EDT
Active, not recruiting No phase listed Observational

Characterizing Outcomes and Real-World Experience of Cardiac Physiologic Pacing (The CORE-CPP Study)

NCT06606288
View directory record Official record
Conditions
Heart Failure
Interventions
Conduction system pacing, Bi-ventricular pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Mounds View, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 15, 2026, 11:26 AM EDT