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ClinicalTrials.gov public records Last synced Oct 29, 2026, 10:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 6,046 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Early Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Changes in Children's Sleep Duration and Timing: Effect on Obesity and Type 2 Diabetes Risk

NCT02979860
View directory record Official record
Conditions
Type2 Diabetes, Sleep
Interventions
Sleep duration 90 min, Sleep duration 45 min, Sleep timing
Behavioral
Lead sponsor
Temple University
Other
Eligibility
8 Years to 11 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 29, 2026, 10:45 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Parents Advancing Toddler Health

NCT04824989
View directory record Official record
Conditions
Sleep Problem, Behavior, Child
Interventions
Sleep Health in Preschoolers (SHIP), Family Check-Up (FCU), Oral Health, Child Safety, and Environmental Health Intervention (Active Control)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Months to 48 Months
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Denver, Colorado • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches

NCT06187662
View directory record Official record
Conditions
Blood Culture Rates, Antibiotic Stewardship, Implementation Science
Interventions
Checklist, Targeted Messaging
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
8
States / cities
Los Angeles, California • San Francisco, California • Wilmington, Delaware + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 29, 2026, 10:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Best Rest: Rest Time Before Blood Pressure Measurement Trial

NCT04031768
View directory record Official record
Conditions
Hypertension, Blood Pressure, Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions
Timing of rest prior to blood pressure measurement
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Oct 29, 2026, 10:45 PM EDT
Completed Phase 3 Interventional Results available

Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)

NCT00461591
View directory record Official record
Conditions
Bladder Cancer
Interventions
Apaziquone, Placebo, TURBT
Drug · Procedure
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
74
States / cities
Anchorage, Alaska • Phoenix, Arizona • Sun City, Arizona + 68 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Oct 29, 2026, 10:45 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

DECAMP-2: Screening of Patients With Early Stage Lung Cancer or at High Risk for Developing Lung Cancer

NCT02504697
View directory record Official record
Conditions
Pulmonary Disease
Interventions
Biosamples from airway and blood
Other
Lead sponsor
Boston University
Other
Eligibility
50 Years to 79 Years
Enrollment
665 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2027
U.S. locations
15
States / cities
Los Angeles, California • San Diego, California • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Not listed Phase 4 Interventional

Early Caffeine in Preterm Neonates

NCT03086473
View directory record Official record
Conditions
BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity, Hemodynamic Instability, Intubation
Interventions
Caffeine Citrate, Placebo (Normal Saline)
Drug
Lead sponsor
Jennifer Shepherd
Other
Eligibility
Up to 1 Day
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 29, 2026, 10:45 PM EDT
Completed No phase listed Observational

Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)

NCT02071056
View directory record Official record
Conditions
Leptomeningeal Metastasis
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Oct 29, 2026, 10:45 PM EDT
Completed Not applicable Interventional

Assessment of the Decision-making Impact of the Breast Cancer Index in Recommending Extended Adjuvant Endocrine Therapy for Patients With Early Stage ER-positive Breast Cancer

NCT02057029
View directory record Official record
Conditions
Breast Cancer, Early Stage Estrogen Receptor (ER) Positive Breast Cancer
Interventions
BCI Assay Results
Behavioral
Lead sponsor
Yale University
Other
Eligibility
Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 29, 2026, 10:45 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid Telehealth

NCT05743439
View directory record Official record
Conditions
Intellectual Disability, Speech and Language Disorder
Interventions
Early Augmentative and Alternative Communication (AAC) Intervention
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
24 Months and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 29, 2026, 10:45 PM EDT
Completed Phase 1 Interventional

Response of Brain Metastases After Gamma-Knife Radiosurgery Using Dynamic Susceptibility-weighted Contrast-enhanced Perfusion Magnetic Resonance Imaging

NCT02311556
View directory record Official record
Conditions
Brain Metastases
Interventions
dynamic susceptibility-weighted contrast-enhanced perfusion magnetic resonance imaging
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2017 · Synced Oct 29, 2026, 10:45 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

NCT03937453
View directory record Official record
Conditions
Pancreatic Cancer, Pancreatic Neoplasms, Diabetes Mellitus
Interventions
MRI/MRCP
Diagnostic Test
Lead sponsor
Nuvance Health
Other
Eligibility
50 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
2
States / cities
New Haven, Connecticut • Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Completed Not applicable Interventional

Adaptive Implementation to Optimize Delivery of Obesity Prevention Practices in Early Care and Education Settings

NCT05050539
View directory record Official record
Conditions
Obesity, Childhood, Nutrition Aspect of Cancer
Interventions
Low Intensity, High Intensity
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
3 Years and older
Enrollment
1,613 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Motor Progression in Parkinson's Disease

NCT02769039
View directory record Official record
Conditions
Parkinson's Disease
Interventions
No intervention. Observational studies of sleep, movement and brain imaging
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Oct 29, 2026, 10:45 PM EDT
Recruiting Phase 2 Interventional

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

NCT07291297
View directory record Official record
Conditions
Sarcoma Metastatic, Sarcoma, Soft Tissue
Interventions
Metformin Hydrochloride ER
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Recruiting Not applicable Interventional

VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

NCT07224256
View directory record Official record
Conditions
Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Quadriplegia/Tetraplegia, Tetraplegic; Paralysis, Stroke
Interventions
N1 Implant, R1 Robot
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 29, 2026, 10:45 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Implementation and Impact of an Enhanced SNAP-Ed Delivered Curriculum in Low-income Preschools

NCT07366437
View directory record Official record
Conditions
Vegetable Acceptance in Early Childhood, Vegetable Intake, Knowledge
Interventions
Rainbow Veggie Club
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
3 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Altoona, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Available No phase listed Expanded access

Early Access Program With Arimoclomol in US Patients With NPC

NCT04316637
View directory record Official record
Conditions
Niemann-Pick Disease, Type C
Interventions
Arimoclomol
Drug
Lead sponsor
ZevraDenmark
Industry
Eligibility
2 Years and older
U.S. locations
13
States / cities
Birmingham, Alabama • Oakland, California • Orange, California + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 29, 2026, 10:45 PM EDT
Terminated Phase 2 Interventional Results available

Miami Membrane for Potency (MMEP) Trial

NCT02710422
View directory record Official record
Conditions
Prostate Cancer
Interventions
Amniotic Membrane Placement, EPIC 26, PSA Measurement, Sexual History Inventory for Men
Biological · Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Oct 29, 2026, 10:45 PM EDT
Not listed Phase 2 Interventional

Computer-Assisted Stop-Smoking Program in Helping Doctors Counsel Patients Who Smoke Cigarettes

NCT00865553
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
computer-assisted smoking cessation intervention, cancer prevention, educational intervention, survey administration
Behavioral · Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 20, 2013 · Synced Oct 29, 2026, 10:45 PM EDT
Recruiting No phase listed Observational

A Novel Approach Utilizing Organ Specific Age Proteomics

NCT06789653
View directory record Official record
Conditions
Breast Cancer
Interventions
p16INK4a mRNA level assessment, organ-specific protein signatures assessment
Diagnostic Test
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
22 Years to 66 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Active, not recruiting Not applicable Interventional

A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer

NCT06813053
View directory record Official record
Conditions
Breast Cancer
Interventions
Decision Aid (DA), Standard of Care (SOC)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado • Highlands Ranch, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Recruiting Phase 4 Interventional

Early Versus Late Adjunctive Vasopressin in Septic Shock

NCT06709573
View directory record Official record
Conditions
Sepsis, Septic Shock
Interventions
vasopressin - early initiation, vasopressin - standard initiation
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 29, 2026, 10:45 PM EDT
Active, not recruiting Phase 3 Interventional

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

NCT06384573
View directory record Official record
Conditions
Alzheimer's Disease, Dementia, Alzheimer's Disease, Familial
Interventions
lecanemab
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
4
States / cities
Birmingham, Alabama • Indianapolis, Indiana • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 29, 2026, 10:45 PM EDT