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ClinicalTrials.gov public records Last synced Oct 14, 2026, 2:14 PM EDT

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Showing 313–336 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Time-Restricted Feeding on Fat Loss and Cardiometabolic Risk Factors in Overweight Adults

NCT03459703
View directory record Official record
Conditions
Obesity
Interventions
Early Time-Restricted Feeding, Control Schedule, Structured Weight Loss Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients

NCT06002269
View directory record Official record
Conditions
Bladder Cancer, Cystectomy, Chemotherapy
Interventions
Dietary and Exercise Intervention
Combination Product
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Results available

ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss

NCT02518685
View directory record Official record
Conditions
Obesity
Interventions
TransPyloric Shuttle, Sham procedure, Lifestyle Counseling
Device · Behavioral
Lead sponsor
BaroNova, Inc.
Industry
Eligibility
22 Years to 60 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
Scottsdale, Arizona • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Results available

Promoting Successful Weight Loss in Primary Care in Louisiana

NCT02561221
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 75 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PilAm Go4Health Weight Loss Program to Prevent Heart Disease

NCT02290184
View directory record Official record
Conditions
Type2 Diabetes
Interventions
PilAm Go4Health Weight-loss Program, Active Control
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Postpartum Weight Loss in Overweight Women

NCT00212251
View directory record Official record
Conditions
Obesity
Interventions
moderate exercise and healthy, low-fat diet
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Leisure-time Activity and Nutrition Program

NCT01142206
View directory record Official record
Conditions
Obesity
Interventions
Dietary, Physical Activity, TV Watching + Physical Activity
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
21 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 14, 2026, 2:14 PM EDT
Terminated Not applicable Interventional

Development of Novel Behavioral Intervention for Sustainable Weight Loss in Hispanic Adults With Obesity

NCT03978416
View directory record Official record
Conditions
Obesity
Interventions
Healthy Weight for Living for Hispanics
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 14, 2026, 2:14 PM EDT
Not listed Phase 3 Interventional

A Weight-Loss Program in Helping Obese Black Women Lose Weight

NCT00859989
View directory record Official record
Conditions
Breast Cancer, Obesity, Weight Changes
Interventions
behavioral dietary intervention, exercise intervention, telephone-based intervention, counseling intervention, educational intervention, immunoenzyme technique, laboratory biomarker analysis, questionnaire administration, study of socioeconomic and demographic variables, evaluation of cancer risk factors, support group therapy
Behavioral · Other · Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition

NCT02437643
View directory record Official record
Conditions
Dynapenia, Obesity
Interventions
Weight Loss, Dairy Protein, Low intensity exercise
Behavioral · Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gender- and Culturally-Sensitive Weight Loss Intervention for Hispanic Males

NCT02783521
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Counseling sessions, Wait List Control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Effects of Journaling on Weight Loss

NCT01660685
View directory record Official record
Conditions
Overweight, Obese
Interventions
Tracking, Journaling, Website, Enhanced Usual Care
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2013 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Phase 4 Interventional Results available

Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity

NCT03799198
View directory record Official record
Conditions
Obesity
Interventions
Weight Management Program (WMP), Medication for chronic weight management (Rx)
Other · Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Cancer Survival Through Weight Loss and Exercise

NCT01217216
View directory record Official record
Conditions
Breast Cancer Survivors
Interventions
Group-based Intervention, Telephone-based Intervention
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
30 Years to 75 Years · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 14, 2026, 2:14 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Treating Binge Eating and Obesity Digitally in Women

NCT05693896
View directory record Official record
Conditions
Binge Eating, Binge-Eating Disorder, Weight Gain Prevention, Obesity
Interventions
Centering Appetite
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Exercise Dose-Response Effects in Prediabetes

NCT00962962
View directory record Official record
Conditions
Pre-Diabetes
Interventions
Aerobic Exercise, Exercise and Diet
Behavioral
Lead sponsor
Duke University
Other
Eligibility
45 Years to 75 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Phase 3 Interventional Results available

A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects

NCT00532779
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Naltrexone SR 16 mg/Bupropion SR 360 mg /day, Naltrexone SR 32 mg/Bupropion SR 360 mg /day, Placebo, Ancillary therapy
Drug · Behavioral
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,742 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
34
States / cities
Birmingham, Alabama • Fairhope, Alabama • Chandler, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2014 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

NCT03146156
View directory record Official record
Conditions
Obesity, Lifestyle-related Condition, Macrosomia, Fetal
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
4
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Families Improving Together (FIT) for Weight Loss

NCT01796067
View directory record Official record
Conditions
Overweight, Obese
Interventions
Motivational and Family Weight Loss, Basic Health Education, Online Intervention, Online Control
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
11 Years to 16 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Oct 14, 2026, 2:14 PM EDT
Terminated Not applicable Interventional

Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery

NCT01329692
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Lifestyle counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 8, 2012 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifestyle Education for Activity and Nutrition for a Leaner You

NCT00957008
View directory record Official record
Conditions
Body Weight Changes, Overweight
Interventions
Group weight loss program, Group weight loss program plus use of the Senseware Armband, Use of the senseware armband alone program
Behavioral · Other · Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Lifestyle, Eating, and Activity Patterns

NCT00944099
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Behavioral weight loss intervention
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 14, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Mobile Lifestyle Intervention for Food and Exercise Study

NCT05176847
View directory record Official record
Conditions
Overweight and Obesity, Type2 Diabetes
Interventions
Podcasts and tips of the day (within app), mLIFE app (self-regulation features), mLIFE app (social support features), standard mLIFE app (social support features)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
243 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 14, 2026, 2:14 PM EDT
Active, not recruiting Phase 3 Interventional

A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight

NCT05726227
View directory record Official record
Conditions
Obesity
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
6 Years to 18 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
24
States / cities
Escondido, California • New Haven, Connecticut • Columbus, Georgia + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 14, 2026, 2:14 PM EDT