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ClinicalTrials.gov public records Last synced Oct 22, 2026, 9:29 PM EDT

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Showing 433–456 of 686 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Fluid Management Clear all
Recruiting Phase 4 Interventional

Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers

NCT05217160
View directory record Official record
Conditions
Wound of Skin, Burns
Interventions
KeraStat® Gel with Morphine application, KeraStat® Gel application
Drug
Lead sponsor
The Metis Foundation
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Study of CD388 Intramuscular or Subcutaneous Administration in Healthy Subjects

NCT05285137
View directory record Official record
Conditions
Healthy
Interventions
CD388 Injection, Saline placebo
Combination Product · Drug
Lead sponsor
Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Mediterranean Diet Intervention to Improve Gastrointestinal Function in Parkinson's Disease a Randomized, Controlled, Clinical Trial

NCT04683900
View directory record Official record
Conditions
Parkinson Disease
Interventions
Standard of care + Mediterranean diet (intervention), Standard of care (control)
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 85 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Oct 22, 2026, 9:29 PM EDT
Terminated Phase 4 Interventional Results available

NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures

NCT04905563
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Acetaminophen-Hydrocodone, Acetaminophen and Ibuprofen
Drug
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
4 Years to 13 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 22, 2026, 9:29 PM EDT
Completed No phase listed Observational

Monitoring Subjects With Fluid-Management Issues In the Home Environment

NCT02190877
View directory record Official record
Conditions
Heart Failure, Hypertension
Interventions
Not listed
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
21 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Oct 22, 2026, 9:29 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Acute Normovolemic Hemodilution on Urine Neutrophil Gelatinase-associated Lipocalin Levels

NCT05349292
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
ANH
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 22, 2026, 9:29 PM EDT
Active, not recruiting Phase 3 Interventional

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

NCT06321601
View directory record Official record
Conditions
Vasculitis
Interventions
Avacopan
Drug
Lead sponsor
Amgen
Industry
Eligibility
6 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
10
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Minneapolis, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children

NCT02687464
View directory record Official record
Conditions
Appendicitis
Interventions
Non-operative treatment, Appendectomy
Other · Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
5 Years to 16 Years
Enrollment
978 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 22, 2026, 9:29 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of a Herbal Tincture on Energy Levels, Weight Management, and Markers of Metabolic Health

NCT06949540
View directory record Official record
Conditions
Stress, Fatigue
Interventions
Blue Burn Tincture
Dietary Supplement
Lead sponsor
Apothekary
Industry
Eligibility
30 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Safety, Tolerability, and Fecal Pharmacokinetics of BX002-A in Healthy Adults

NCT04737876
View directory record Official record
Conditions
Healthy Volunteers
Interventions
BX002-A, Placebo
Biological · Other
Lead sponsor
BiomX, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 22, 2026, 9:29 PM EDT
Terminated Not applicable Interventional Results available

Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)

NCT01128413
View directory record Official record
Conditions
Shock
Interventions
Cheetah NICOM® PLRT, USCOM ® (Ultrasound Cardiac Output Monitor), Inferior Vena Cava (IVC) Ultrasound Collapsibility, CURVES Questionnaire, Lactate Clearance, 500ml Normal Saline Bolus, Clinician Discretion Intravenous Fluid Management
Device · Behavioral · Biological
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 1, 2016 · Synced Oct 22, 2026, 9:29 PM EDT
Completed No phase listed Observational

Evaluation of the Efficacy of Diafert in Predicting Embryos' Potential to Develop to the Blastocyst Stage

NCT02788617
View directory record Official record
Conditions
Infertility
Interventions
Diafert
Device
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
9
States / cities
Encino, California • Clearwater, Florida • Hoffman Estates, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Saline Against Lactated Ringers or Plasmalyte in the Emergency Department

NCT02614040
View directory record Official record
Conditions
Critical Illness, Acute Kidney Injury
Interventions
0.9% Saline, Physiologically-balanced isotonic crystalloid
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
14,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration

NCT03416582
View directory record Official record
Conditions
Lung Cancer, Mucositis Oral, Dehydration, Head and Neck Cancer
Interventions
Symptom Management Education and Nurse Coaching, Drinks Diary
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Phase 2 Interventional Results available

A Phase 2b Study of UGN-102 for Low Grade Intermediate Risk Non-Muscle-Invasive Bladder Cancer

NCT03558503
View directory record Official record
Conditions
Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
Interventions
UGN-102
Drug
Lead sponsor
UroGen Pharma Ltd.
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
17
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Loma Linda, California + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 22, 2026, 9:29 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes

NCT02121184
View directory record Official record
Conditions
Pregnancy, Labor Pain
Interventions
Routine oxytocin, Half-dose oxytocin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Biomarkers in Obstructive Sleep Apnea

NCT02325687
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lumbar Puncture (Standard-of-Care)
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 84 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Oct 22, 2026, 9:29 PM EDT
Withdrawn No phase listed Observational

Registry of Pancreatic Fluid Collections and Pancreatic Cysts

NCT02422095
View directory record Official record
Conditions
Pancreatic Fluid Collections, Pancreatic Cyst
Interventions
Endoscopy-based (EUS-guided) interventions for pancreatic fluid collections, EUS of pancreatic cysts
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Phase 2 Interventional Results available

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome

NCT00570128
View directory record Official record
Conditions
Down Syndrome
Interventions
Donepezil HCl, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
10 Years to 17 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
31
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Relative Bioavailability of Two Formulations of BIIB104 and Assess the Effect of Food on the Pharmacokinetics of BIIB104 Following Administration of a Single, Fixed, Oral Dose of BIIB104 in Healthy Participants

NCT05152485
View directory record Official record
Conditions
Healthy Volunteers
Interventions
BIIB104 Reference Formulation, BIIB104 Test Formulation
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Symptom Management Program for Hemodialysis Patients

NCT01620580
View directory record Official record
Conditions
Haemodialysis-induced Symptom
Interventions
Self-management, Dietary Information
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2012 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)

NCT02547779
View directory record Official record
Conditions
Critical Illness, Acute Kidney Injury
Interventions
0.9% Saline, Physiologically-balanced isotonic crystalloid
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
10,421 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 22, 2026, 9:29 PM EDT
Not listed Not applicable Interventional

Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

NCT06600724
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer Due to Type 2 Diabetes Mellitus, Foot Ulcer, Diabetic, Foot Ulcer
Interventions
Standard of Care, EPIEFFECT, EPIXPRESS
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 9:29 PM EDT
Completed Phase 3 Interventional Results available

Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables

NCT03054922
View directory record Official record
Conditions
Anesthesia
Interventions
Normal Saline, Lactated Ringer, Normosol-R Inj
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 21 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 22, 2026, 9:29 PM EDT