Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:34 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 151 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: HDL Clear all

Conditions: Hyperlipidemia
Interventions: Placebo, MBX-8025, Atorvastatin; Drug
Lead sponsor: Gilead Sciences; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 28
States / cities: Birmingham, Alabama • Phoenix, Arizona • Huntington Beach, California + 24 more

Conditions: Intracranial Arteriosclerosis, Stroke
Interventions: Ticagrelor + Aspirin, Rivaroxaban + Aspirin, Clopidogrel + Aspirin, Risk Factor Management; Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 30 Years and older
Enrollment: 1,683 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 114
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 89 more

Conditions: Lipoprotein Disorder
Interventions: No intervention is involved in this study; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2029
U.S. locations: 2
States / cities: Dallas, Texas

Conditions: Healthy Participants
Interventions: LY2484595, Placebo, Ketoconazole; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: Daytona Beach, Florida • Dallas, Texas

Conditions: Metabolic Syndrome
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 35 Years to 50 Years · Female only
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: HDL Cholesterol
Interventions: Not listed
Lead sponsor: KineMed; Industry
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis, Myocardial Infarction
Interventions: Simvastatin and Extended-Release niacin, Simvastatin; Drug
Lead sponsor: University of Washington; Other
Eligibility: 45 Years and older
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 24
States / cities: Birmingham, Alabama • Phoenix, Arizona • Long Beach, California + 13 more

Conditions: Metabolic Syndrome, Hypertriglyceridemia
Interventions: omega-3 acid ethyl esters, extended release niacin, placebo, combined treatment; Drug
Lead sponsor: University of South Dakota; Other
Eligibility: 40 Years to 69 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Cardiovascular Disease Prevention
Interventions: Nutrition bar; Other
Lead sponsor: UCSF Benioff Children's Hospital Oakland; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Oakland, California

Conditions: Atherosclerosis
Interventions: extended release niacin, ezetimibe; Drug
Lead sponsor: Walter Reed Army Medical Center; Federal
Eligibility: 30 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Takoma Park, Maryland

Conditions: Cardiovascular Disease, Hyperlipidemia
Interventions: Avocado Diet, Lower-Fat Diet, Moderate Fat Diet; Other
Lead sponsor: Penn State University; Other
Eligibility: 21 Years to 70 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Age-Related Macular Degeneration
Interventions: Goji berry, Fiber; Dietary Supplement
Lead sponsor: University of California, Davis; Other
Eligibility: 65 Years to 95 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Severe Sepsis, Septic Shock, Sepsis
Interventions: Not listed
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Healing Wound
Interventions: Orascopic HDL 3.0 Loupes, Semorr DOM3000D Operation Microscope; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Atherosclerosis, Diabetes Mellitus, Obesity, Dyslipidemia, Hypertension
Interventions: Exercise, Weight Loss; Behavioral
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years and older · Female only
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Hypercholesterolemia
Interventions: BiosLife Complete, Placebo; Dietary Supplement
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 85 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Coronary Artery Disease
Interventions: Niaspan; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Dyslipidaemias
Interventions: GW590735, fenofibrate; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 45
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 38 more

Conditions: HIV Infections, Cardiovascular Disease
Interventions: rosuvastatin; Drug
Lead sponsor: University of Hawaii; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2009
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Healthy
Interventions: 3H-Cholesterol; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cholesterol, HDL, Lipid Metabolism, Inborn Errors, Tangier Disease, LCAT Deficiency, Cholesteryl Ester Transfer Protein (CETP) Deficiency
Interventions: 3H-cholesterol bound to albumin; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity (BMI Equal to or >30), Immune Function, HDL, Gut Microbiome, Healthy Adult Participants
Interventions: Egg whites, Whole eggs; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 50 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Hypolipoproteinemia, Hypercholesterolemia, Dyslipidemia, Hyperlipidemia
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 759 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1976
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Stroke
Interventions: Standard, Incentive, Salience, Incentive + Salience; Behavioral
Lead sponsor: Indiana Institute for Medical Research; Other
Eligibility: 18 Years and older
Enrollment: 641 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

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Safety and Benefit of MBX-8025 With and Without Commonly Used Statins in Moderately Overweight Patients With High Cholesterol

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Extreme Lipids Repository

A Study of LY2484595 on Pharmacokinetics in Healthy Participants

Early Vascular Wall Changes by Magnetic Resonance Imaging (MRI) in Metabolic Syndrome Versus Metabolically Normal Pre-Menopausal Women: A Pilot Study

Effect of Niaspan on Cholesterol in Men

Plaque Inflammation and Dysfunctional HDL in AIM-HIGH

Niacin, N-3 Fatty Acids and Insulin Resistance

Impact of a Nutritional Supplement on Metabolic Health

Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis

The Effect of Avocado on Cardiovascular Disease (CVD) Risk Factors

Effects of Goji vs. Fiber on Macular Degeneration

The Role of Dysfunctional HDL in Severe Sepsis

Longitudinal Monitoring of Microsurgical Socket Augmentation Healing With Ultrasonography

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

The Effect of BiosLife on Serum Lipids

Benefit of Elevation of HDL-C on Cardiovascular Outcomes in Women

Dyslipidemia Study Investigating The Increase In "Good Cholesterol"

Effect of Rosuvastatin on Endothelial Function

Reverse Cholesterol Transport (RCT) Study

Mendelian Reverse Cholesterol Transport Study

Investigation of Egg Intake and the Relationship Between Gut Microbiome, Metabolic, and Immune Profiles

Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins

MINDSPACE Strategy for Risk Optimization