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Showing 1–24 of 1,068 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Heart Ultrasound Clear all
Completed Not applicable Interventional Results available

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

NCT03015194
View directory record Official record
Conditions
Mitral Valve Failure
Interventions
Edwards SAPIEN 3 transcatheter heart valve, ASHI INTECC Astato XS 20
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Phase 1 Interventional Results available

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers

NCT03388632
View directory record Official record
Conditions
Metastatic Solid Tumors, Treatment-Refractory Cancers
Interventions
rhIL-15, Ipilimumab, Nivolumab, Tumor biopsies, EKG, ECHO, CT Scan
Drug · Procedure · Diagnostic Test
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 7, 2026, 7:24 AM EDT
Active, not recruiting Not applicable Interventional

REDUCE LAP-HF TRIAL II

NCT03088033
View directory record Official record
Conditions
Heart Failure
Interventions
IASD System II implant, intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)
Device · Other
Lead sponsor
Corvia Medical
Industry
Eligibility
40 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
44
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 36 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 7, 2026, 7:24 AM EDT
Recruiting Not applicable Interventional

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

NCT07286578
View directory record Official record
Conditions
Cardiovascular Diseases, Myocardial Ischemia, Heart Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases, Coronary Artery Disease
Interventions
CT(Computed Tomography) guided Percutaneous Coronary Intervention, IVUS (Intravascular Ultrasound) guided Percutaneous Coronary Intervention
Device
Lead sponsor
Fundación EPIC
Other
Eligibility
18 Years to 85 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
5
States / cities
Boston, Massachusetts • Minneapolis, Minnesota • Jersey City, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 7, 2026, 7:24 AM EDT
Not listed Not applicable Interventional

Does Ultrasound Assessment for Extravascular Lung Water and IVC Measurement Affect Outcomes in Inpatient Heart Failure Management?

NCT04436718
View directory record Official record
Conditions
Acute Decompensated Heart Failure
Interventions
Daily pocus exam
Diagnostic Test
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Not applicable Interventional Results available

RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt

NCT04604015
View directory record Official record
Conditions
Embolic Stroke of Undetermined Source, Transient Ischemic Attack, Right-To-Left Atrial Shunt, Patent Foramen Ovale
Interventions
NeuralBot Investigational System, Transthoracic Echocardiography (TTE)
Diagnostic Test
Lead sponsor
NeuraSignal Inc dba NovaSignal
Industry
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Phoenix, Arizona • Portland, Oregon • Chattanooga, Tennessee + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SHAPE:SeeingtheHeartwithAIPoweredEcho

NCT03705650
View directory record Official record
Conditions
Cardiac Disease
Interventions
Limited Echocardiogram
Diagnostic Test
Lead sponsor
Sara Guttas
Industry
Eligibility
65 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winfield, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Sep 7, 2026, 7:24 AM EDT
Recruiting Phase 1 Interventional

Studying TAK-243 in Patients With Advanced Cancer

NCT06223542
View directory record Official record
Conditions
Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Indolent Non-Hodgkin Lymphoma, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm
Interventions
Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging, UAE Inhibitor TAK-243
Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 7, 2026, 7:24 AM EDT
Terminated Not applicable Interventional Results available

Assessment of Pulmonary Congestion During Cardiac Hemodynamic Stress Testing

NCT04019613
View directory record Official record
Conditions
Dyspnea, Heart Failure With Preserved Ejection Fraction
Interventions
Lung ultrasound
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Not applicable Interventional Results available

DIstal vs Proximal Radial Artery Access for Cath

NCT04318990
View directory record Official record
Conditions
Coronary Angiography, Coronary Angioplasty
Interventions
Distal radial artery access, Proximal radial artery surgery
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Not applicable Interventional Results available

GE CVUS Device Evaluation

NCT05340244
View directory record Official record
Conditions
Echocardiography
Interventions
Investigational ultrasound exam
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Sep 7, 2026, 7:24 AM EDT
Recruiting Not applicable Interventional

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

NCT05459233
View directory record Official record
Conditions
Aortic Valve Stenosis, Aortic Valve Regurgitation, Prosthesis Failure
Interventions
Doppler-echocardiography, Invasive hemodynamic measurements
Procedure
Lead sponsor
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Other
Eligibility
18 Years and older
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
San Francisco, California • Hollywood, Florida • Royal Oak, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Intrafetal Digoxin as an Adjuvant for Dilation and Evacuation at 20 to 24 Weeks' Gestation

NCT03136068
View directory record Official record
Conditions
Abortion
Interventions
Digoxin, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
3
States / cities
Long Beach, California • San Francisco, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Sep 7, 2026, 7:24 AM EDT
Terminated Not applicable Interventional

Multi-Center Trial Utilizing Low Frequency Ultrasound in the Prevention of Post-Contrast Acute Kidney Injury

NCT04877847
View directory record Official record
Conditions
Contrast-induced Nephropathy, Chronic Kidney Diseases
Interventions
Low-frequency therapeutic ultrasound (LOTUS), LOTUS System with Ultrasound Disabled
Device
Lead sponsor
Sonogenix
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Detroit, Michigan • Petoskey, Michigan • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 7, 2026, 7:24 AM EDT
Not listed No phase listed Observational

Gut Microbiome and Ventricular Arrhythmias

NCT04466072
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Gut Microbiome
Interventions
Stool test for microbial analysis
Diagnostic Test
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2022 · Synced Sep 7, 2026, 7:24 AM EDT
Completed No phase listed Observational

Cystic Breast Masses by Contrast Enhanced Ultrasound (CEUS)

NCT02887937
View directory record Official record
Conditions
Breast Cancer
Interventions
Definity
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Sep 7, 2026, 7:24 AM EDT
Recruiting No phase listed Observational

Comparative Imaging Assessment of Valvular Heart Disease

NCT04126018
View directory record Official record
Conditions
Valve Heart Disease, Aortic Stenosis, Aortic Regurgitation
Interventions
MRI with strain measurement, Echocardiography
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 7, 2026, 7:24 AM EDT
Not listed No phase listed Observational

Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery Disease

NCT04732091
View directory record Official record
Conditions
Acute Myocardial Infarction, Unstable Angina
Interventions
Therapeutic ultrasound with 20 usec
Procedure
Lead sponsor
University of Sao Paulo General Hospital
Other
Eligibility
30 Years and older
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 7, 2026, 7:24 AM EDT
Completed Phase 2 Interventional Results available

Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus

NCT01958320
View directory record Official record
Conditions
Patent Ductus Arteriosus, Surgery, Necrotizing Enterocolitis, Intestinal Perforation
Interventions
pharmacologic treatment of the PDA, no pharmacologic treatment of the PDA, NSAID
Other · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Days to 14 Days
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
13
States / cities
San Diego, California • San Francisco, California • San Jose, California + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Sep 7, 2026, 7:24 AM EDT
Withdrawn Not applicable Interventional

Effects of Mitral Valve Repair With the Geoform Ring on Cardiomyopathy

NCT00428103
View directory record Official record
Conditions
Mitral Valve Regurgitation, Congestive Heart Failure, Cardiomyopathy
Interventions
3 dimensional echocardiography
Procedure
Lead sponsor
Juan Crestanello, MD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2013 · Synced Sep 7, 2026, 7:24 AM EDT
Enrolling by invitation Phase 2 Interventional

Chronic Exogenous Ketosis in HFpEF

NCT06937320
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction (HFPEF), Heart Failure With Normal Ejection Fraction, Heart Failure, Diastolic
Interventions
Exogenous Ketone Drink, Placebo
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 7, 2026, 7:24 AM EDT
Active, not recruiting No phase listed Observational

International Bicuspid Aortic Valve Consortium (BAVCon)

NCT01980797
View directory record Official record
Conditions
Bicuspid Aortic Valve Disease, Thoracic Aortic Disease in Patients With a Bicuspid Aortic Valve
Interventions
Not listed
Lead sponsor
Boston University
Other
Eligibility
8 Years to 90 Years
Enrollment
6,464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2028
U.S. locations
5
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 7, 2026, 7:24 AM EDT
Recruiting Phase 2 Interventional

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

NCT06918431
View directory record Official record
Conditions
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Lymphoblastic Lymphoma
Interventions
Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide, Cytarabine, Daunorubicin Hydrochloride, Dexamethasone, Echocardiography, Lumbar Puncture, Mercaptopurine, Methotrexate, Positron Emission Tomography, Rituximab, Vincristine Sulfate
Drug · Procedure · Biological
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 54 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
8
States / cities
Phoenix, Arizona • Duarte, California • Irvine, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 7, 2026, 7:24 AM EDT
Withdrawn No phase listed Observational

Ventricular Remodeling In Patients With Aortic Stenosis Assessed Echocardiography

NCT00774657
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Not listed
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Sep 7, 2026, 7:24 AM EDT