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ClinicalTrials.gov public records Last synced Nov 6, 2026, 6:23 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1417–1440 of 2,754 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: High Activity Clear all

Conditions: BRAF V600E Mutation
Interventions: Dabrafenib Mesylate, Trametinib Dimethyl Sulfoxide; Drug
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Stroke
Interventions: Actuated Virtual Keyboard (AVK) system, Occupational Therapy (OT); Behavioral
Lead sponsor: North Carolina State University; Other
Eligibility: 21 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: PTSD
Interventions: TMS 1 hz, Sham TMS; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 19 Years to 70 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: White River Junction, Vermont

Conditions: Methamphetamine Use Disorder
Interventions: EFT, high frequency rTMS, sham frequency rTMS; Behavioral · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Exercise
Interventions: High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT); Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 35 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, Motivation
Interventions: Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET), Mobile Health intervention; Device · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Melanoma (Skin Cancer)
Interventions: UV Real-Time Alerts, Track Your Sun Protection, Current Conditions, Health Coaching, Action Planning, Core Components; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Chicago, Illinois • Salt Lake City, Utah

Conditions: Overweight and Obesity
Interventions: Intervention Targeting Stress and Emotion Regulation, Intervention Targeting Motivation and Self-efficacy for Weight Management, Intervention for Normalization of Eating, Intervention Targeting Physical Activity and Sleep; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alzheimer Disease, Mild Cognitive Impairment, Adherence
Interventions: Improving Cognitive Aging through Nutrition (ICAN) Adherence Program, Improving Cognitive Aging through Nutrition, Mediterranean diet; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 55 Years to 85 Years
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Bladder Cancer
Interventions: HS-410, Placebo, BCG; Biological
Lead sponsor: Heat Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 19
States / cities: Los Angeles, California • Sherman Oaks, California • Torrance, California + 16 more

Conditions: Delirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane Block
Interventions: Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring, Generalized Anxiety Disorder 7-item (GAD-7) scale, Numerical Rating Score (NRS), PROMIS-Pain Interference, Oswestry Disability Index (ODI), Saint Louis University Mental Status Examination (SLUMs), Delirium Rating Scale-Revised-98 (DRS), Telephone Interview for Cognitive Status - Modified (TICS-M), Opioid Equivalents measured by Morphine Milligram Equivalents (MME), Patient Health Questionnaire depression scale (PHQ-8), Pain Catastrophizing, Fear Avoidance Beliefs Questionnaire (FABQ), Opioid Side Effects and Likeability Questionnaire, Daily Pain Trajectory, Tampa Scale of Kinesiophobia, Quality of Recovery 15; Drug · Diagnostic Test · Other
Lead sponsor: University of Iowa; Other
Eligibility: 65 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Dysphagia Following Cerebrovascular Accident
Interventions: high intensity dysphagia therapy; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Muscle Hypotrophy
Interventions: Carnipure AAS, Creatine Monohydrate; Dietary Supplement
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Stroke
Interventions: Robot-Assisted Therapy (RT), Robot & Task-Oriented Training (RT-TOT); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 82 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cognitive Impairment, Mild, Cognitive Decline
Interventions: Walking conversational reminiscence; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 65 Years to 110 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Parkinson Disease, Sleep Disturbance
Interventions: Tailored Lighting Intervention (LIT), Actigraph; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Traumatic Stress Disorder, Problem Drinking
Interventions: App-based intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older · Female only
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Glucose Intolerance
Interventions: High Intensity Interval Training (HIIT), Moderate-intensity continuous training (MICT); Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 40 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Parkinson's Disease, Deep Brain Stimulation
Interventions: Exercise; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Diabetes
Interventions: Parent Computer-Delivered Motivational Intervention, Parent & Child Computer-Delivered Motivational Intervention, Computer-Delivered Information; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 10 Years to 13 Years
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: COVID-19, Long Haul
Interventions: Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine, Biopsychological, Behavioral (e.g., Psychotherapy, Lifestyle Counseling), Genetic (including gene transfer, stem cell and recombinant DNA), Multidisciplinary approach; Drug · Diagnostic Test · Biological + 3 more
Lead sponsor: Well- Konnect Healthcare Services and Research Firm; Network
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2030
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: High Grade Glioma, Meningioma, Embryonal Tumor, Medulloblastoma, Anaplastic Ependymoma, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Malignant Glioma, Recurrent Medulloblastoma, Recurrent Primary Central Nervous System Neoplasm, Refractory Diffuse Intrinsic Pontine Glioma, Refractory Malignant Glioma, Refractory Medulloblastoma, Refractory Primary Central Nervous System Neoplasm
Interventions: LUTATHERA® (Lutetium Lu 177 dotatate); Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 4 Years to 39 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2033
U.S. locations: 4
States / cities: Aurora, Colorado • Cincinnati, Ohio • Columbus, Ohio + 1 more

Conditions: Pulmonary Disease, Chronic Obstructive (COPD), Cognitive Impairment
Interventions: Neuropsychological Assessment, Spirometry, Arterial Blood Gas, Diffusion Capacity of the Lung for Carbon Monoxide, 6 Minute Walk Test, Systemic Vascular Measures, Blood Biomarkers, Symptom Questionnaire Measures, Brain MRI; Behavioral · Procedure · Diagnostic Test + 1 more
Lead sponsor: Karin Hoth; Other
Eligibility: 30 Years to 85 Years
Enrollment: 170 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: COVID-19 Pneumonia
Interventions: PF-06650833, Matching Placebo; Drug
Lead sponsor: Giovanni Franchin, M.D, Ph.D; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: The Bronx, New York

Search by objective public record fields.

Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

Finger Movement Training After Stroke

Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD

A Pilot Study of Transcranial Magnetic Stimulation Plus Episodic Future Thinking for Methamphetamine Use Disorder

High-Intensity Functional Training (HIFT) vs Moderate-Intensity Continuous Training (MICT) in College Students

Stroke and CPAP Outcome Study 3

Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions

Control Systems Engineering for Weight Loss Maintenance

A Scalable Nutrition Adherence Intervention

A Phase 1/2 Study of HS-410 in Patients With Non-Muscle Invasive Bladder Cancer After TURBT

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients

Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy Men

Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke

Efficacy of a Multimodal Brain Health Intervention for Older African Americans

Lighting Intervention to Improve Sleep

Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)

Metabolic Adaptations in Response to High Intensity Interval Training in Obese Adults

Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS

Computerized Intervention of Parental Involvement in Diabetes Care of Their Child

Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

COPD-Related Physiology and the Brain

IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.