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ClinicalTrials.gov public records Last synced Nov 2, 2026, 9:55 AM EST

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Showing 1–24 of 70 matching trials from the live ClinicalTrials.gov search.
Conditions
Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer Due to Type 2 Diabetes Mellitus, Foot Ulcer, Diabetic, Foot Ulcer
Interventions
Standard of Care, EPIEFFECT, EPIXPRESS
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Conditions
Intra-Amniotic Infection of Foetus
Interventions
Perilynx Analyzer to measure AF and VF fluid
Diagnostic Test
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
5
States / cities
Long Beach, California • Shreveport, Louisiana • Newark, New Jersey + 2 more
Conditions
Venous Stasis Ulcer, Venous Leg Ulcer
Interventions
MTX-001 (human amniotic fluid)
Biological
Lead sponsor
Merakris Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
12
States / cities
Tucson, Arizona • Castro Valley, California • Los Angeles, California + 8 more
Completed Not applicable Interventional Accepts healthy volunteers

An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis

NCT02318511
Conditions
Osteoarthritis
Interventions
Knee injection, ReNu amniotic allograft, placebo saline, Hyaluronic Acid
Procedure · Other · Device
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 8 more
Conditions
Labor, Premature, Preterm Premature Rupture of the Membranes, Infection, Inflammation, Chorioamnionitis
Interventions
amniocentesis, N-acetylcysteine or placebo
Procedure · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • Columbus, Ohio
Conditions
Wound, Foot, Diabetic Foot Ulcer (DFU), Venus Leg Ulcer
Interventions
Microlyte®, IP 1: Membrane Wrap - Hydro
Device
Lead sponsor
Capsicure, LLC
Network
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
7
States / cities
San Diego, California • Coral Gables, Florida • Miami, Florida + 3 more
Conditions
Lung Diseases, Interstitial
Interventions
Matrix
Biological
Lead sponsor
Maule Stem Cell Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Venice, Florida
Conditions
Osteoarthritis, Knee
Interventions
Acellular Amniotic Membrane Derived Allograft Injection (NuDYN)
Other
Lead sponsor
Illinois Center for Orthopaedic Research and Education
Other
Eligibility
21 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Westmont, Illinois
Conditions
Fetal Growth Abnormality, Amniotic Fluid; Disorder
Interventions
Point-of-care ultrasound (POC-US), Routine antenatal care, Formal ultrasound
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Conditions
Intrauterine Growth Retardation
Interventions
selective laser photocoagulation of communicating vessels, Expected Management
Procedure · Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
2
States / cities
Los Angeles, California • Tampa, Florida
Conditions
Discordance in Lung Maturity in Diamniotic Twins
Interventions
aspiration of amniotic fluid
Procedure
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Intervertebral Disc Disease, Intervertebral Disc Degeneration, Spondylosis, Spondylolisthesis, Spinal Stenosis
Interventions
NuCel with Autograft
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
21 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

COVID-19 and Obstetric Transmission

NCT04418557
Conditions
COVID, Pregnancy Complications
Interventions
RT-PCR and antibody testing
Diagnostic Test
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Completed No phase listed Observational Accepts healthy volunteers Results available

Analysis of ROM Plus to Detect Rupture of Membranes

NCT01366443
Conditions
Rupture of Amniotic Membranes
Interventions
Sterile speculum exam, ROM Plus Exam, Chart Reveiw
Procedure
Lead sponsor
Clinical Innovations, LLC
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
288 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Osteoarthritis, Hip
Interventions
ReNu™ Injection
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Redwood City, California • Chicago, Illinois
Completed Phase 1Phase 2 Interventional

Zofin to Treat COVID-19 Long Haulers

NCT05228899
Conditions
COVID-19
Interventions
Zofin, Placebo
Drug · Other
Lead sponsor
ZEO ScientifiX, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Newport Beach, California • North Hollywood, California • Miami, Florida + 1 more
Conditions
Myelomeningocele
Interventions
Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix, Untreated contemporaneous cohort
Biological · Other
Lead sponsor
University of California, Davis
Other
Eligibility
19 Weeks to 25 Weeks
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Sacramento, California
Terminated Phase 1Phase 2 Interventional Results available

Processed Amniotic Fluid (pAF) for the Treatment of Chronic Wounds

NCT04438174
Conditions
Wounds and Injuries
Interventions
Processed Amniotic Fluid, Standard of Care Wound Treatment Regimen
Drug · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Phase 1 Interventional Results available

Renal Anhydramnios Fetal Therapy

NCT03101891
Conditions
Anhydramnios, Potter Syndrome, Lung Hypoplasia, Multicystic Dysplastic Kidney, Multicystic Renal Dysplasia, Bilateral, Lower Urinary Tract Obstructive Syndrome, Fetal Renal Anomaly
Interventions
Serial amnioinfusions with isotonic fluid, Spinal needle, Isotonic fluid
Procedure · Device · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
9
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 6 more
Completed No phase listed Observational

Studying Fetal Breathing Patterns

NCT00066976
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
San Diego, California • Bethesda, Maryland
Conditions
Knee Osteoarthritis
Interventions
Amniotic Suspension Allograft, Placebo
Biological · Drug
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
38
States / cities
Birmingham, Alabama • Mobile, Alabama • Glendale, Arizona + 30 more
Conditions
Diabetic Foot Ulcer
Interventions
AMNIOEXCEL Plus Amniotic Membrane, A Marketed Comparator, Standard of Care
Other · Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
21 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
7
States / cities
Fresno, California • Los Angeles, California • Gainesville, Georgia + 3 more
Conditions
PROM
Interventions
Use of Rapid Immunoassay Tests for the Detection of PROM
Device
Lead sponsor
Clinical Innovations, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
3
States / cities
Newark, Delaware • Camden, New Jersey • Salt Lake City, Utah
Conditions
Pregnancy Related, Cesarean Wound Disruption, Cesarean Section; Infection
Interventions
Application of Autologous Amniotic Fluid
Device
Lead sponsor
Recibio, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina