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ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:06 PM EDT

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Showing 1–24 of 243 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ICD Implant Clear all
Completed Phase 2 Interventional

Sleep and Ventricular Arrhythmias Study

NCT02232204
View directory record Official record
Conditions
Cardiac Arrhythmia, Implantable Defibrillator User, Insomnia
Interventions
CBT for Insomnia in ICD Patients (CBT-I-ICD)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 5, 2014 · Synced Oct 21, 2026, 9:06 PM EDT
Completed No phase listed Observational

Implantable Cardiac Defibrillators for the Prevention of Sudden Death in Patients With Cardiac Sarcoidosis

NCT01013311
View directory record Official record
Conditions
Sarcoidosis of the Heart, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

Extravascular ICD Pivotal Study

NCT04060680
View directory record Official record
Conditions
Tachycardia, Ventricular Arrythmia
Interventions
Defibrillation using the Extravascular ICD
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
33
States / cities
Scottsdale, Arizona • La Jolla, California • Redwood City, California + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 21, 2026, 9:06 PM EDT
Completed No phase listed Observational

Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms

NCT00916435
View directory record Official record
Conditions
Congestive Heart Failure, Sudden Cardiac Death, Arrhythmia, Cardiomyopathies
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Oct 21, 2026, 9:06 PM EDT
Completed No phase listed Observational

Assessment of S-ICD Eligibility With 12-Lead ECG

NCT03209726
View directory record Official record
Conditions
Implantable Defibrillator User
Interventions
Not listed
Lead sponsor
Larisa Tereshchenko
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 21, 2026, 9:06 PM EDT
Terminated Not applicable Interventional Results available

Effect of Posture on Left Ventricular (LV) Transvenous Lead Capture Thresholds (EXPECT)

NCT01520714
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Medtronic 4195 active fixation LV lead and Medtronic passive fixation LV lead
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2014 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Phase 4 Interventional Results available

Truncal Ultrasound Guided Regional Anesthesia for Implantation and Revision of Automatic Implantable Cardioverter Defibrillators (AICDs) and Pacemakers in Pediatric Patients

NCT04184349
View directory record Official record
Conditions
Analgesia After Pacemaker, AICDS Implantation Pediatrics
Interventions
LA group, B Group
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
0 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 21, 2026, 9:06 PM EDT
Recruiting Phase 4 Interventional

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

NCT06964464
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction (HFrEF), Sudden Cardiac Death, Ventricular Arrhythmia, Implantable Cardioverter Defibrillator (ICD), Beta-blocker Therapy, Cardiomyopathy
Interventions
Metoprolol Succinate, Carvedilol
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
13
States / cities
Scottsdale, Arizona • Rome, Georgia • Shawnee Mission, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 21, 2026, 9:06 PM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)

NCT07585968
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
6
States / cities
Indianapolis, Indiana • Manhasset, New York • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Phase 2Phase 3 Interventional

A Mindfulness-based Intervention for Treatment of Anxiety in ICD (Implantable Cardioverter Defibrillator) Patients

NCT01035294
View directory record Official record
Conditions
Anxiety Disorder in Conditions Classified Elsewhere
Interventions
mindfulness based intervention (MBI), usual care
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2012 · Synced Oct 21, 2026, 9:06 PM EDT
Terminated Not applicable Interventional Results available

Managed Ventricular Pacing ("MVP") Trial

NCT00281099
View directory record Official record
Conditions
Heart Disease
Interventions
ICD (Implantable Cardioverter Defibrillator)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,031 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
50
States / cities
Anchorage, Alaska • Little Rock, Arkansas • North Little Rock, Arkansas + 47 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2010 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure

NCT05600725
View directory record Official record
Conditions
Cardiomyopathies, Heart Rate, Conditioning
Interventions
novel atrial pacing approach, sham pacing approach
Other
Lead sponsor
Denise Hodgson-Zingman
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 21, 2026, 9:06 PM EDT
Recruiting No phase listed Observational

Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention

NCT00733590
View directory record Official record
Conditions
Heart Failure, Congestive, Death, Sudden, Cardiac, Arrhythmia, Cardiomyopathies
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 85 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2029
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 21, 2026, 9:06 PM EDT
Active, not recruiting Not applicable Interventional

Assessment of Combined CCM and ICD Device in HFrEF

NCT05855135
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
Interventions
OPTIMIZER® Integra CCM-D System (Treatment Arm)
Device
Lead sponsor
Impulse Dynamics
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
59
States / cities
Glendale, Arizona • Mesa, Arizona • Phoenix, Arizona + 40 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

Safety of Body Composition Analysis in Heart Failure Patients With Implantable Cardioverter Defibrillators (ICDs)

NCT01568606
View directory record Official record
Conditions
Heart Failure, Obesity
Interventions
Body Composition Analysis InBody Scale
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 21, 2026, 9:06 PM EDT
Completed No phase listed Observational

3T MRI CIED Post-Approval Study

NCT02969395
View directory record Official record
Conditions
Cardiac Rhythm Disorder
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
118
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 115 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 21, 2026, 9:06 PM EDT
Terminated Phase 1 Interventional

A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT)

NCT05532046
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
BAY2413555 Dose 1, BAY2413555 Dose 2, Placebo to BAY2413555
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 79 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Atlanta, Georgia • Silver Spring, Maryland • Camp Hill, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Proton Particle Therapy for Cardiac Arrhythmia

NCT04392193
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Proton Particle Therapy
Radiation
Lead sponsor
Konstantinos Siontis
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

Heart Rate Response to Regadenoson and Sudden Cardiac Death

NCT01842035
View directory record Official record
Conditions
Left Ventricular Systolic Dysfunction, Sudden Cardiac Death
Interventions
regadenoson
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 21, 2026, 9:06 PM EDT
Completed No phase listed Observational Results available

Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy Post Approval Registry

NCT01294449
View directory record Official record
Conditions
Heart Failure
Interventions
MADIT-CRT ICD, MADIT-CRT CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Oct 21, 2026, 9:06 PM EDT
Withdrawn Not applicable Interventional

Dance4Healing: Explore the Benefits of Tele-Dance in Individuals with an Implantable Cardioverter-defibrillator (ICD)

NCT04678128
View directory record Official record
Conditions
ICD, Anxiety, Patient Engagement
Interventions
Dance4Healing Telehealth Live Zoom Sessions, Dance Buddy
Behavioral
Lead sponsor
Sanjiv Narayan, MD, PhD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 21, 2026, 9:06 PM EDT
Completed No phase listed Observational Results available

Longitudinal Surveillance Study of the 4-SITE Lead/Header System

NCT01596595
View directory record Official record
Conditions
Primary Prevention of Sudden Cardiac Arrest, Secondary Prevention of Sudden Cardiac Arrest
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
1,820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
104
States / cities
Anchorage, Alaska • Glendale, Arizona • Mesa, Arizona + 94 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2021 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Postcards to Improve Remote Monitoring Adherence Among Veterans

NCT06068699
View directory record Official record
Conditions
ICD, Pacemaker DDD, Adherence, Patient
Interventions
Postcard
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
6,351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 21, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

Inappropriate Shock Reduction wIth PARAD+ Rhythm DiScrimination

NCT01410552
View directory record Official record
Conditions
Tachycardia
Interventions
PARADYM DR model 8550; PARADYM CRT model 8750; PARADYM RF DR model 9550; PARADYM RF CRT model 9750; PARADYM RF CRT SonR model 9770
Device
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
1,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
27
States / cities
Mesa, Arizona • Peoria, Arizona • Phoenix, Arizona + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 21, 2026, 9:06 PM EDT