Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 10, 2026, 12:55 AM EDT

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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Left Ventricular Dysfunction, Coronary Artery Disease
Interventions
Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
1,252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
83
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 65 more
Conditions
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Interventions
Impella CP® placement prior to reperfusion with Primary PCI
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
527 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
46
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Tucson, Arizona + 41 more
Active, not recruiting Not applicable Interventional

The Smart Pump Study

NCT04465201
Conditions
Cardiac Output
Interventions
Impella CP with Smart Assist (Circulatory Support System)
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
New Orleans, Louisiana • Boston, Massachusetts • Detroit, Michigan + 2 more
Terminated Not applicable Interventional

The RECOVER IV Trial

NCT05506449
Conditions
ST-segment Elevation Myocardial Infarction (STEMI), Cardiogenic Shock
Interventions
Impella CP®, Standard of Care
Device · Other
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albuquerque, New Mexico
Not listed No phase listed Observational

Protected PCI Study

NCT02831881
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
369 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Detroit, Michigan
Terminated Not applicable Interventional Results available

SHIELD II Clinical Investigation

NCT02468778
Conditions
Coronary Artery Disease
Interventions
HeartMate PHP, Any Abiomed Impella® device approved for use in high-risk PCI
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
58
States / cities
Scottsdale, Arizona • Tucson, Arizona • Los Angeles, California + 43 more
Conditions
Coronary Artery Disease
Interventions
Early Bird® Bleed Monitoring System, Impella®
Device
Lead sponsor
Saranas, Inc.
Industry
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
11
States / cities
Phoenix, Arizona • Tucson, Arizona • Gary, Indiana + 7 more
Conditions
Right Heart Failure
Interventions
IMPELLA® RP
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Detroit, Michigan • Philadelphia, Pennsylvania
Conditions
AMI Cardiogenic Shock
Interventions
Impella
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
18
States / cities
Jonesboro, Arkansas • Orange, California • Torrance, California + 14 more
Terminated Not applicable Interventional Results available

Early Insertion of Axillary Impella® With VA ECMO

NCT04084015
Conditions
Cardiogenic Shock
Interventions
Axillary Impella®
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Percutaneous Large Hole Vascular Closure
Interventions
PPCI, Cardiogenic shock
Device
Lead sponsor
Vivasure Medical Limited
Industry
Eligibility
19 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Ridgewood, New Jersey • Buffalo, New York • Stony Brook, New York + 1 more
Conditions
Cardiac Surgery
Interventions
IMPELLA LP/LD 5.0
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
7
States / cities
Baltimore, Maryland • Boston, Massachusetts • New Brunswick, New Jersey + 3 more
Conditions
Heart Failure, Cardiogenic Shock, Reduced Ejection Fraction Heart Failure
Interventions
Impella 5.5 SmartAssist
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
7
States / cities
Tampa, Florida • Minneapolis, Minnesota • New Brunswick, New Jersey + 4 more
Conditions
Peripartum Cardiomyopathy, Cardiogenic Shock
Interventions
Clinical placement of a temporary IMPELLA® mechanical circulatory support device.
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin