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ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:18 AM EDT

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Showing 25–48 of 109 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: In Vivo Exposure Therapy Clear all
Completed Not applicable Interventional Results available

Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial

NCT03962504
View directory record Official record
Conditions
PTSD
Interventions
trauma-focused treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Charleston, South Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-Based Exposure Treatment for Dental Anxiety

NCT03461016
View directory record Official record
Conditions
Phobic Disorders, Dental Anxiety, Treatment Outcome
Interventions
Exposure Therapy
Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Sep 30, 2026, 1:18 AM EDT
Active, not recruiting Phase 1 Interventional

A Study of Psilocybin for PTSD

NCT06407635
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Psilocybin, Trauma-focused psychotherapy, Standard psychological support
Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD

NCT04961190
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
7
States / cities
Birmingham, Alabama • Menlo Park, California • San Diego, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism

NCT01563003
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder
Interventions
Cognitive Behavioral Therapy, Treatment as usual
Other
Lead sponsor
University of South Florida
Other
Eligibility
11 Years to 16 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2015 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Phase 3 Interventional Results available

Estrogen and Fear in PTSD

NCT04192266
View directory record Official record
Conditions
PTSD
Interventions
Estradiol, Placebo oral tablet, Prolonged Exposure (PE) therapy
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy

NCT04549493
View directory record Official record
Conditions
PTSD
Interventions
Exposure Therapy
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 64 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional

Efficacy of 60-minute Versus 90-minute Sessions in Treating PTSD Using Prolonged Exposure

NCT01911585
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2021 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Phase 2 Interventional

Development of an Anxiety Sensitivity-Based Intervention for Substance Use and Anxiety Comorbidity

NCT02667015
View directory record Official record
Conditions
Other (or Unknown) Substance Use Disorders
Interventions
Psychotherapy (Anxiety Sensitivity Intervention)
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 28, 2016 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

NCT01178385
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder
Interventions
Cognitive-behavioral therapy, Treatment as Usual
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 11 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Apr 2, 2013 · Synced Sep 30, 2026, 1:18 AM EDT
Recruiting Not applicable Interventional

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

NCT07116109
View directory record Official record
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Interventions
Transcranial Direct Current Stimulation (tDCS), Massed-Prolonged Exposure (PE), Sham Transcranial Direct Current Stimulation (tDCS)
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional Results available

Comparison of Treatment for Hoarding Disorder

NCT02040805
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Sep 30, 2026, 1:18 AM EDT
Active, not recruiting No phase listed Observational

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

NCT05145062
View directory record Official record
Conditions
Blood and Lymphatic Diseases
Interventions
BIVV003, ST-400
Drug
Lead sponsor
Sangamo Therapeutics
Industry
Eligibility
18 Years to 45 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2038
U.S. locations
7
States / cities
Oakland, California • Sacramento, California • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 30, 2026, 1:18 AM EDT
Not yet recruiting Not applicable Interventional

A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients

NCT04584125
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% with UV light, Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% without UV light
Drug
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years to 50 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Recruiting Not applicable Interventional

Safety and Efficacy of Head-lice Treatments Elimax Green Lotion and Walgreens Lice Killing Shampoo

NCT07191457
View directory record Official record
Conditions
Head Lice
Interventions
Elimax Green Lotion with Emogreen, Walgreens Lice Killing Shampoo
Device · Drug
Lead sponsor
Oystershell NV
Industry
Eligibility
6 Months and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Enid, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 30, 2026, 1:18 AM EDT
Recruiting Not applicable Interventional

Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder

NCT05858346
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Transdiagnostic Behavior Therapy, Cognitive Behavioral Therapy for Social Anxiety Disorder
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional Results available

Group Treatment for PTSD: A Randomized Clinical Trial With Veterans

NCT01544088
View directory record Official record
Conditions
PTSD
Interventions
Group Cognitive Behavioral Treatment (GCBT), Present Centered Group Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 30, 2026, 1:18 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

TDCS-Augmented Prolonged Exposure Therapy

NCT04327362
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD, Anxiety, Depression
Interventions
Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional

Combining Acceptance and Commitment Therapy With Exposure and Response Prevention to Enhance Treatment Engagement

NCT03343106
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
ACT plus ERP, ERP alone
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Logan, Utah
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Sep 30, 2026, 1:18 AM EDT
Recruiting Not applicable Interventional

Adapting Exposure for Adolescent AN

NCT07188155
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Exposure Therapy for Anorexia (Exp-AN)
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
14 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 30, 2026, 1:18 AM EDT
Not listed Not applicable Interventional

Anti-phobic and Safety Behaviors in the Treatment of Acrophobia

NCT02085343
View directory record Official record
Conditions
Specific Phobia
Interventions
EXP, EXP + SBF, EXP + SBF + AA
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional Results available

Optimizing Treatment Response in VA Specialized Intensive/Inpatient PTSD Programs

NCT03533608
View directory record Official record
Conditions
PTSD
Interventions
Group PE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Ann Arbor, Michigan • Battle Creek, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Sep 30, 2026, 1:18 AM EDT
Completed Not applicable Interventional

Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms

NCT01347749
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mindfulness & Compassion Meditation-based Exposure Therapy, Present Centered Therapy for PTSD
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Sep 30, 2026, 1:18 AM EDT
Not yet recruiting Not applicable Interventional

A Randomized Controlled Efficacy Trial of a Telemedicine-based Virtual Reality Clinic for the Treatment of Phobias

NCT07558824
View directory record Official record
Conditions
Specific Phobia, Animal
Interventions
Telemedicine-Based Virtual Reality Exposure Therapy, Telemedicine-Based Exposure Therapy Using Photos and Videos
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 30, 2026, 1:18 AM EDT