Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 1:30 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1201–1224 of 1,792 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Intervention 2 - Sham Treatment Clear all

Conditions: Depression
Interventions: Armodafinil, Placebo; Drug
Lead sponsor: Cephalon; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 399 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 28
States / cities: Birmingham, Alabama • Sherman Oaks, California • Temecula, California + 21 more

Conditions: Laryngeal Stenosis, Subglottic Stenosis, Tracheal Stenosis
Interventions: Mitomycin -C, Saline application; Drug · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking Cessation
Interventions: Propranolol, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Angina
Interventions: Ranolazine, Sugar pill; Drug
Lead sponsor: North Florida Foundation for Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Irritable Bowel Syndrome, Dermatographism, Post-prandial Diarrhea
Interventions: Antihistamine, Placebo; Drug
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee, Lower Limb Amputation Above Knee, Knee Arthropathy, Shoulder Arthroplasty, Rotator Cuff Repair, Video-Assisted Thoracoscopic Surgery (VATS), Skin Grafting
Interventions: Cryoneurolysis (active), Sham cryoneurolysis procedure; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Rectal Microbicides
Interventions: Tenofovir 1% gel, 2% N-9 gel, HEC Placebo gel; Drug
Lead sponsor: CONRAD; Other
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 3
States / cities: Birmingham, Alabama • Boston, Massachusetts • Pittsburgh, Pennsylvania

Conditions: Sleep, Sedation Complication
Interventions: MRI, Quantitative Sensory Testing (QST), Home sleep study, Acoustic stimulation (65 decibels or db) up-slope of EEG with QST, Acoustic stimulation (65db) down-slope of EEG with QST, 0 db with QST, Dexmedetomidine, Breathe-Squeeze Task; Radiation · Diagnostic Test · Other + 1 more
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 40 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Stroke
Interventions: transcranial random noise stimulation and functional electrical stimulation facilitated task practice; Device
Lead sponsor: Amit Sethi; Other
Eligibility: 18 Years to 80 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Fibromyalgia
Interventions: Traditional Acupuncture, Sham Treatment; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 75 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Convergence Insufficiency
Interventions: Anodal-Transcranial Direct Current Stimulation, Office-Based Vergence/Accommodative Therapy, Sham Transcranial Direct Current Stimulation; Device · Behavioral
Lead sponsor: Midwestern University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Downers Grove, Illinois

Conditions: Nicotine Dependence
Interventions: Naltrexone, Transdermal nicotine replacement, Behavioral counseling; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Cessation, Smoking, Nicotine Dependence
Interventions: CIS - telephone cessation quitline counseling, Lozenge - nicotine mini-lozenges, Emails - Brief smoking prevention messages, Full website - standard smokefree.gov website content, Lite website - lite version of smokefree.gov, Full mailed booklet - NCI's detailed 36-page quit guide, brief mailed booklet - smaller version of NCI's booklet; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 1,034 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Major Depressive Disorder, Menopause, Perimenopause
Interventions: Pregnenolone, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 40 Years to 67 Years · Female only
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Multiple Sclerosis
Interventions: Venoplasty, Sham procedure (non-treatment); Procedure
Lead sponsor: Manish Mehta, MD; Other
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Albany, New York

Conditions: Erectile Dysfunction
Interventions: Injection of adipose derived cells into penis; Device
Lead sponsor: Tissue Genesis; Industry
Eligibility: 21 Years and older · Male only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 5
States / cities: San Diego, California • Washington D.C., District of Columbia • Gainesville, Florida + 2 more

Conditions: Acute Mountain Sickness
Interventions: ambrisentan and theophylline, placebo; Drug
Lead sponsor: University of Montana; Other
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Missoula, Montana

Conditions: Asthma
Interventions: Active Air Purifier, Placebo Air Purifier; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 8 Years to 17 Years
Enrollment: 198 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: COVID-19, SARS-CoV 2
Interventions: Canakinumab Injection 600mg, Canakinumab Injection 300mg, Placebos; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Weston, Florida • Cleveland, Ohio

Conditions: Dry Eye
Interventions: EBI-005, Placebo; Drug
Lead sponsor: Eleven Biotherapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 12
States / cities: Birmingham, Alabama • Newport Beach, California • Hamden, Connecticut + 9 more

Conditions: Malaria
Interventions: PfRAS, Placebo, Challenge; Biological · Other
Lead sponsor: U.S. Army Medical Research and Development Command; Federal
Eligibility: 18 Years to 50 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Healthy Aging
Interventions: Roll Tilt Training, Translation Training, Both Tilt and Translation Training, Placebo Control; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 65 Years to 89 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Stimulant Use Disorder, Substance-related Disorders
Interventions: Repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Childhood Obesity
Interventions: Phentermine, Placebo; Drug
Lead sponsor: Russell McCulloh, MD; Network
Eligibility: 12 Years to 17 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 8
States / cities: Wilmington, Delaware • Louisville, Kentucky • Baton Rouge, Louisiana + 5 more

Search by objective public record fields.

Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/Day) as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Study of Mitomycin-C Application in Laryngotracheal Stenosis

Memory Reconsolidation Blockade as a Novel Intervention for Nicotine Dependence

Ranolazine Among Unrevascularized Chronic Stable Angina Patients

Antihistamines in the Treatment of Irritable Bowel Syndrome With Diarrhea

Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study

Rectal Safety and Acceptability Study of Tenofovir 1% Gel

Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine

t-RNS After Hand Recovery in Chronic Stroke

Developing Biomarkers for Fibromyalgia

Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency

Targeted Interventions for Weight-Concerned Smokers

Evaluation of National Cancer Institute (NCI) Smoking Intervention Resources

A Neurosteroid Intervention for Menopausal and Perimenopausal Depression

Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients

Evaluation of the Tissue Genesis Icellator Cell Isolation System to Treat Erectile Dysfunction

Drug Combination on Exercise Performance at High Altitude

AIRWEIGHS: Investigating Obesity as a Susceptibility Factor for Air Pollution in Childhood Asthma

Canakinumab in Covid-19 Cardiac Injury (The Three C Study)

Study of EBI-005 in Dry Eye Disease (DED)

Immunization Via Mosquito Bite With Radiation-attenuated Sporozoites

Effect of Vestibular Perceptual Learning on Vestibular Thresholds and Balance

Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation

Phentermine's Impact on Treatment in Teens