Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 2:50 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 745–768 of 1,141 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Isotonic solution Clear all

Conditions: Genital Herpes Simplex Type 2
Interventions: GEN-003 Vaccine (30μg of each antigen), GEN-003 Vaccine (60μg of each antigen), Matrix-M2 Adjuvant (25μg), Matrix-M2 Adjuvant (50μg), Matrix-M2 Adjuvant (75μg), Placebo; Biological
Lead sponsor: Genocea Biosciences, Inc.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 310 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 16
States / cities: Birmingham, Alabama • San Diego, California • San Francisco, California + 12 more

Conditions: Delayed Graft Function, Kidney Transplantation, Complement Activity
Interventions: Eculizumab, Normal Saline; Drug
Lead sponsor: Heeger, Peter, M.D.; Individual
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 5
States / cities: New Haven, Connecticut • New York, New York • Cleveland, Ohio + 1 more

Conditions: Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
Interventions: Phenylephrine, Epinephrine, Albumin, Voluven, Normal Saline, Packed Red Blood Cells, FloTrac Monitor; Drug · Other · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 15 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Sleep Deprivation, Delirium
Interventions: Dexmedetomidine, Placebo; Drug · Other
Lead sponsor: Maisonneuve-Rosemont Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Recovery Following Cholecystectomy
Interventions: Acetaminophen, normal saline; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 3
States / cities: Newark, New Jersey • Brooklyn, New York

Conditions: Obesity
Interventions: Normal Saline 0.9% Infusion Solution Bag; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Atropine Bioequivalence
Interventions: Atropine Sulfate Ophthalmic Solution USP, 1%, Atropine Sulfate Injection, USP 8 mg/20 mL (0.4 mg/mL); Drug
Lead sponsor: Biomedical Advanced Research and Development Authority; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Lenexa, Kansas

Conditions: Migraine Disorders
Interventions: Botulinum toxin type A Dose 1, Botulinum toxin type A Dose 2, Placebo (Normal Saline); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 22
States / cities: Phoenix, Arizona • Fullerton, California • Oceanside, California + 19 more

Conditions: Thyroid Eye Disease, Graves' Orbitopathy
Interventions: Teprotumumab, Placebo; Biological · Other
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 9
States / cities: Beverly Hills, California • Los Angeles, California • Coral Gables, Florida + 6 more

Conditions: Hyperemesis Gravidarum, Nausea Gravidarum, Vomiting of Pregnancy
Interventions: Capsaicin Topical Cream, Metoclopramide, Ondansetron, Lactated Ringers, Intravenous; Drug
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: PTR-01, Normal saline; Drug
Lead sponsor: Phoenix Tissue Repair, Inc.; Industry
Eligibility: 16 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Redwood City, California • Aurora, Colorado • Philadelphia, Pennsylvania

Conditions: Carpal Tunnel Syndrome
Interventions: Vancomycin, Cefazolin, Saline Solution; Drug
Lead sponsor: WellSpan Health; Other
Eligibility: 18 Years and older
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: York, Pennsylvania

Conditions: Postural Tachycardia Syndrome
Interventions: Saline, Placebo; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2031
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Elective Orthopedic Surgery
Interventions: Midazolam, Propofol, Saline; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hypofibrinogenemia, Afibrinogenemia, Bleeding Disorders
Interventions: RiaStAP, Saline; Drug
Lead sponsor: Nicklaus Children's Hospital f/k/a Miami Children's Hospital; Other
Eligibility: 1 Day to 1 Year
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Miami, Florida

Conditions: Non-infected Diabetic Foot Ulcer, Diabetic Foot, Diabetic Wound, Diabetic Foot Ulcer, Non-ischemic Diabetic Foot Ulcer
Interventions: BR-AM, Standard Care; Other
Lead sponsor: BioStem Technologies; Industry
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 17
States / cities: Guntersville, Alabama • Mesa, Arizona • Tucson, Arizona + 14 more

Conditions: Suicidal Ideation
Interventions: Ketamine, Normal Saline; Drug
Lead sponsor: Allen Richert; Other
Eligibility: 18 Years to 64 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Acute Bronchiolitis
Interventions: Hypertonic saline and epinephrine, Normal saline and epinephrine; Drug
Lead sponsor: Le Bonheur Children's Hospital; Other
Eligibility: 6 Weeks to 2 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Gastrointestinal Hemorrhage (Clinically Important, Upper)
Interventions: Placebo (0.9% saline), Pantoprazole; Drug
Lead sponsor: McMaster University; Other
Eligibility: 18 Years and older
Enrollment: 4,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: COVID-19, Coronavirus, Coronavirus Infection
Interventions: Convalescent Plasma, Saline solution; Biological · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 941 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 9
States / cities: New Haven, Connecticut • Miami, Florida • New York, New York + 5 more

Conditions: Pulmonary Hypertension
Interventions: SonoVue, Placebo; Drug
Lead sponsor: Bracco Diagnostics, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Teaneck, New Jersey

Conditions: Post Partum Hemorrhage, Fibrinolysis; Hemorrhage, Blood Loss
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Breast Cancer
Interventions: AST-301(pNGVL3-hICD), rhuGM-CSF, Placebo, Pembrolizumab, Capecitabine; Biological · Drug
Lead sponsor: Aston Sci. Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 10
States / cities: Chandler, Arizona • La Jolla, California • Tampa, Florida + 7 more

Conditions: Chronic Migraine
Interventions: OnabotulinumtoxinA, Normal saline (placebo); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine

Eculizumab for Prevention of Delayed Graft Function (DGF) in Kidney Transplantation

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?

Multi-dose Acetaminophen for Patients Undergoing General Anesthesia

The Natriuretic Peptide Response to Saline Infusion

Sublingual Atropine Bioequivalence by Route of Administration (SABER)

A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents With Chronic Migraine

Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study

Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy

A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Preoperative Antibiotics for Carpal Tunnel Release Surgery

Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

Efficacy of Propofol or Midazolam Compare to Placebo for Preoperative Medication

Human Fibrinogen Concentrate in Pediatric Cardiac Surgery

Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AM

The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.

7% Hypertonic Saline for Acute Bronchiolitis

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial

CONTAIN COVID-19: Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients

Safety of SonoVue on Pulmonary Hemodynamics

Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery

Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Patients With Breast Cancer

Use of a Treatment Benefit Questionnaire in Patients With Chronic Migraine Treated With OnabotulinumtoxinA (BOTOX®)