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ClinicalTrials.gov public records Last synced Oct 30, 2026, 9:02 AM EDT

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Showing 97–120 of 571 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Loop Clear all
Completed Not applicable Interventional

A Comparison of Techniques for Treating Skin Abscesses

NCT01897675
View directory record Official record
Conditions
Cutaneous Abscess
Interventions
Incision and Drainage with packing (wick) placement, Abscess drainage with loop placement
Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
20 Years and older
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2018 · Synced Oct 30, 2026, 9:02 AM EDT
Terminated Not applicable Interventional Results available

Bovine Carotid Artery Biologic Graft and Expanded Polytetrafluoroethylene for Permanent Hemodialysis Access

NCT03300024
View directory record Official record
Conditions
End Stage Renal Disease, Hemolysis, Arteriovenous Graft
Interventions
Expanded polytetrafluoroethylene Graft, Bovine Carotid Artery Graft
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Phase 3 Interventional Results available

TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure

NCT03296813
View directory record Official record
Conditions
Heart Failure
Interventions
Torsemide, Furosemide
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2,973 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
60
States / cities
Alexander City, Alabama • Huntsville, Alabama • Tucson, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Hybrid Closed Loop Pivotal Trial in Type 1 Diabetes

NCT02463097
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Insulin Pump
Device
Lead sponsor
Medtronic MiniMed, Inc.
Industry
Eligibility
14 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
Escondido, California • Palo Alto, California • Aurora, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response

NCT00355797
View directory record Official record
Conditions
Bradycardia
Interventions
Closed Loop Stimulation (CLS), Standard Rate Adaptive (R) Technology, Non-rate adaptive (DDD) pacing
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,491 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
99
States / cities
Albertville, Alabama • Gadsden, Alabama • Jasper, Alabama + 82 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 30, 2026, 9:02 AM EDT
Recruiting No phase listed Observational

Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes

NCT05849753
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Child, Delivery of Health Care, Equipment and Supplies
Interventions
Advanced artificial pancreas closed-loop technology
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Jacksonville, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of an Online Parenting Training

NCT05111886
View directory record Official record
Conditions
Behavior Problem, Behavior, Child, Parents, Parent-Child Relations
Interventions
Communication Skills Training, eHealth GenPMTO, Written Referral Process, One Session Education about Resources, Survey of Experience
Behavioral · Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years to 100 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

NCT06386588
View directory record Official record
Conditions
Schizophrenia
Interventions
Closed loop auditory stimulation during sleep
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Phase 3 Interventional

At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run Adaptation

NCT02705053
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
CGM and Insulin Pump, Closed-Loop Control System
Device
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
21 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
3
States / cities
Santa Barbara, California • Rochester, Minnesota • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2016 · Synced Oct 30, 2026, 9:02 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Personalized Performance Optimization Platform

NCT06979570
View directory record Official record
Conditions
Sensory Science, Performance Assessment, Countermeasure Evaluation, Neurocognitive Function, Psychological Factors
Interventions
AttentivU
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Cambridge, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Adaptive Closed Loop Neuromodulation and Neural Signatures of Parkinson's Disease

NCT02384421
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Adaptive DBS (Activa PC+S Neurostimulator), Continuous DBS (Activa PC+S Neurostimulator)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 30, 2026, 9:02 AM EDT
Recruiting Phase 3 Interventional

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

NCT07185997
View directory record Official record
Conditions
Non-Small-Cell Lung Cancer, Metastatic Non-Small-Cell Lung Cancer, Advanced Non-Small-Cell Lung Cancer, EGFR P-Loop and Alpha C-Helix Compressing, EGFR PACC, EGFR Uncommon Mutations
Interventions
Firmonertinib, EGFR-TKI inhibitor based on investigator's choice
Drug
Lead sponsor
ArriVent BioPharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
21
States / cities
Fullerton, California • Los Angeles, California • Orange, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

HIRREM Developmental Study

NCT02709369
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes, Headache, Traumatic Brain Injury, Post Concussion Symptoms
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 24, 2019 · Synced Oct 30, 2026, 9:02 AM EDT
Terminated Not applicable Interventional Results available

Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure

NCT03645681
View directory record Official record
Conditions
Kidney Failure, Chronic, Renal Dialysis
Interventions
InnAVasc arteriovenous graft surgical implant
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
7
States / cities
San Diego, California • Flint, Michigan • Greenwood, Mississippi + 4 more
Source: ClinicalTrials.gov public record
Updated May 9, 2025 · Synced Oct 30, 2026, 9:02 AM EDT
Enrolling by invitation Not applicable Interventional

Pilot Study to Evaluate Changes in Intra-Epidermal Nerve Fiber Density (IENFD) in Patients With Small-Fiber Neuropathy

NCT07704931
View directory record Official record
Conditions
Small Fiber Neuropathy
Interventions
Evoke SCS system
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Withdrawn Phase 4 Interventional

Comparing Diuretic Strategies in Hospitalized Heart Failure

NCT03999216
View directory record Official record
Conditions
Heart Failure
Interventions
Loop Diuretics vs. loop + thiazide diuretics
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 30, 2026, 9:02 AM EDT
Active, not recruiting Not applicable Interventional

Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).

NCT06246526
View directory record Official record
Conditions
Pain, Chronic Pain, Neuropathic Pain
Interventions
Evoke
Device
Lead sponsor
Saint Francis Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional

Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer

NCT00003384
View directory record Official record
Conditions
Precancerous Condition, Stage 0 Cervical Cancer
Interventions
Cervical Papanicolaou Test, Conization, Laboratory Biomarker Analysis
Other · Procedure
Lead sponsor
Gynecologic Oncology Group
Network
Eligibility
18 Years and older · Female only
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 29, 2015 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine

NCT04206059
View directory record Official record
Conditions
Sleep, Sedation Complication
Interventions
MRI, Quantitative Sensory Testing (QST), Home sleep study, Acoustic stimulation (65 decibels or db) up-slope of EEG with QST, Acoustic stimulation (65db) down-slope of EEG with QST, 0 db with QST, Dexmedetomidine, Breathe-Squeeze Task
Radiation · Diagnostic Test · Other + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Not yet recruiting Not applicable Interventional

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

NCT06898138
View directory record Official record
Conditions
Epilepsy
Interventions
Brain Interchange System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Completed Not applicable Interventional

A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus During Meal Challenges

NCT03848767
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
AID System, Insulin Lispro
Device · Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Renton, Washington
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 30, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional

Insulin Delivery With Self-Adjusting Closed-Loop and Behavioral Glycemic Control Enhanced by Prediction

NCT07507708
View directory record Official record
Conditions
Type 1 Diabetes (T1D)
Interventions
Automated Insulin Delivery (AID), AIDANET + Fully Closed Loop (FCL), AIDANET + Anticipatory Closed Loop (ACL)
Device
Lead sponsor
Sue Brown
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Active, not recruiting Not applicable Interventional

The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

NCT03582891
View directory record Official record
Conditions
Parkinson Disease, Dystonia
Interventions
Summit RC+S for Motor, 8-week pilot trial of Closed-loop vs. Open-loop Stimulation, Summit RC+S for Sleep
Device · Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 30, 2026, 9:02 AM EDT
Suspended Not applicable Interventional

Non-Invasive Electrical and Magnetic Neuromodulation in Persons With Chronic Spinal

NCT05994846
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
RISES-T System
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 30, 2026, 9:02 AM EDT