- Conditions
- Brain Death, Organ Donation, Organ Transplant Failure or Rejection
- Interventions
- Open lung protective ventilation, Conventional ventilation
- Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 13 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 4
- States / cities
- Los Angeles, California • Palo Alto, California • San Francisco, California + 1 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–14
of 14
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Acute Respiratory Failure
- Interventions
- Noninvasive positive pressure ventilation (NIPPV), Vapotherm
- Device
- Lead sponsor
- Vapotherm, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 204 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 5
- States / cities
- Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more
- Conditions
- Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
- Interventions
- Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
- Other · Drug
- Lead sponsor
- University Health Network, Toronto
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6,250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 26
- States / cities
- Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
- Conditions
- Acute Lung Injury, Adult Respiratory Distress Syndrome, Kidney Injury
- Interventions
- Volume-Cycled Assist-Control (AC) mode, Airway Pressure Release Ventilation (APRV) mode
- Device
- Lead sponsor
- University of Tennessee, Chattanooga
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Chattanooga, Tennessee
- Conditions
- Anesthesia, Congenital Heart Disease
- Interventions
- Low Vt protocol, High Vt protocol
- Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- Not listed
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Mechanical Ventilation Complication
- Interventions
- weaning
- Procedure
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- Not listed
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Morbid Obesity, Surgery, General Anesthesia
- Interventions
- Higher PEEP, Lower PEEP
- Procedure
- Lead sponsor
- Technische Universität Dresden
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,013 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Rochester, Minnesota
- Conditions
- One-Lung Ventilation
- Interventions
- PEEP level, Use of recruitment maneuvers
- Procedure
- Lead sponsor
- Technische Universität Dresden
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • New York, New York • Cleveland, Ohio
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), VV ECMO
- Interventions
- Mechanical Power Targeted Ventilation
- Procedure
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Obesity, Morbid, Ventilator-Induced Lung Injury, Respiratory Failure
- Interventions
- Esophageal balloon, Intervention Spontaneous Breathing Trial (SBT) and Extubation, Control Spontaneous Breathing Trial and Extubation, Intervention Weaning after Tracheostomy, Control Weaning after Tracheostomy
- Device · Procedure
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Greenville, North Carolina
- Conditions
- Acute Respiratory Distress Syndrome
- Interventions
- Esophageal-pressure guided mechanical ventilation, High PEEP mechanical ventilation
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 202 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 10
- States / cities
- La Jolla, California • Stanford, California • Orlando, Florida + 6 more
- Conditions
- Lung Injury, Preterm Birth
- Interventions
- Positive End-Expiratory Pressure (PEEP)
- Procedure
- Lead sponsor
- Murdoch Childrens Research Institute
- Other
- Eligibility
- 23 Weeks to 28 Weeks
- Enrollment
- 906 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2028
- U.S. locations
- 4
- States / cities
- Little Rock, Arkansas • San Diego, California • Indianapolis, Indiana + 1 more
- Conditions
- Transpulmonary Pressure, Pressure.Rate Product, Guide to Mechanical Ventilator Management, Extubation Readiness
- Interventions
- Transpulmonary Pressure measurement
- Device
- Lead sponsor
- Children's Hospital Los Angeles
- Other
- Eligibility
- 1 Week to 18 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2024
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Respiratory Failure, Intracranial Hypertension
- Interventions
- Esophageal Balloon catheter
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- Not listed
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina