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Showing 1–24 of 101 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mechanical thrombectomy Clear all
Completed No phase listed Observational

New York City Mobile Interventional Stroke Team

NCT03048292
View directory record Official record
Conditions
Acute Stroke
Interventions
Acute Endovascular Stroke Treatment
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 3, 2026, 6:06 AM EDT
Not yet recruiting Phase 4 Interventional

Second Line Endovascular Treatment in Acute DVT

NCT06486181
View directory record Official record
Conditions
Deep Venous Thrombosis
Interventions
Thrombolysis/Thrombectomy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational Results available

Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

NCT04693767
View directory record Official record
Conditions
Ischemic Stroke, Intracranial Hematoma
Interventions
Mechanical thrombectomy, Minimally invasive surgery
Device · Other
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
27
States / cities
Mesa, Arizona • Phoenix, Arizona • Newark, Delaware + 24 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational Results available

Trevo® Retriever Registry Post Market Surveillance

NCT02040259
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Not listed
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
Not listed
Enrollment
2,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
47
States / cities
Mesa, Arizona • Phoenix, Arizona • Castro Valley, California + 40 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational

Penumbra Imaging Collaborative Study (PICS)

NCT00785161
View directory record Official record
Conditions
Stroke
Interventions
Penumbra System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 11, 2018 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting No phase listed Observational

Michigan Initial Experience Using Tigertriever for Thrombectomy

NCT07363525
View directory record Official record
Conditions
Blood Clot, Thrombectomy, Ischemic Stroke
Interventions
Mechanical Thrombectomy
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Phase 2Phase 3 Interventional

ACTISAVE: ACuTe Ischemic Stroke Study Evaluating Glenzocimab Used as Add-on Therapy Versus placEbo

NCT05070260
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Intravenous glenzocimab (ACT017) 1000 mg, Intravenous Placebo
Drug
Lead sponsor
Acticor Biotech
Industry
Eligibility
18 Years and older
Enrollment
438 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
9
States / cities
Bradenton, Florida • St. Petersburg, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Phase 2Phase 3 Interventional

Minocycline in Stroke Study at Maimonides

NCT07237048
View directory record Official record
Conditions
Stroke, Ischemia Stroke, Hemorrhagic Strokes, Mortality, Morbidity, Cerebrovascular Accident (Stroke), Intracerebral Haemorrhage (ICH)
Interventions
Minocycline 200mg
Drug
Lead sponsor
Joyce Chen
Other
Eligibility
18 Years and older
Enrollment
1,164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

Analysis of Revascularization in Ischemic Stroke With EmboTrap

NCT02488915
View directory record Official record
Conditions
Stroke, Ischemia
Interventions
EmboTrap® Revascularization Device
Device
Lead sponsor
Neuravi Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
9
States / cities
Los Angeles, California • San Jose, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2018 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Phase 4 Interventional Results available

Assess the Penumbra System in the Treatment of Acute Stroke

NCT01429350
View directory record Official record
Conditions
Ischemic Stroke
Interventions
intravenous (IV) recombinant human tissue plasminogen activator (rtPA), Penumbra System
Drug · Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
4
States / cities
Denver, Colorado • Gainesville, Florida • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

NCT05701917
View directory record Official record
Conditions
Venous Thromboembolism, Deep Venous Thrombosis, Post-Thrombotic Syndrome
Interventions
ClotTriever System, Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.
Device · Drug
Lead sponsor
Inari Medical
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
48
States / cities
Scottsdale, Arizona • Tucson, Arizona • Orange, California + 43 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Active, not recruiting No phase listed Observational

Risk Factors and Outcomes of Ischemic Stroke Associated With Tandem or Isolated Cervical Artery Occlusion in Anterior and Posterior Circulation

NCT06965036
View directory record Official record
Conditions
Acute Ischemic Stroke Related to Tandem Occlusion, Acute Ischemic Stroke Due to Isolated Cervical Artery Occlusion
Interventions
Not listed
Lead sponsor
Azienda Unità Sanitaria Locale della Romagna
Other
Eligibility
Not listed
Enrollment
2,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 3, 2026, 6:06 AM EDT
Terminated Not applicable Interventional Results available

Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia

NCT00869375
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Endovascular peripheral intervention
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

The Pivotal Study of RapidPulseTM Aspiration System

NCT06029491
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
RapidPulseTM Aspiration System
Device
Lead sponsor
RapidPulse, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
18
States / cities
Torrance, California • New Haven, Connecticut • Jacksonville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Phase 1 Interventional

Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

NCT05871606
View directory record Official record
Conditions
Cerebrovascular Disorders, Acute Cerebrovascular Disease
Interventions
iNO
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

EnDOvascular Therapy for Late WiNdow IschEmic Stroke Patients Selected bY AutoMatic Plain ComputErized Tomography

NCT07001852
View directory record Official record
Conditions
Stroke Acute
Interventions
Endovascular Therapy (Mechanical Thrombectomy), Standard Medical Management
Other
Lead sponsor
Santiago Ortega Gutierrez
Other
Eligibility
18 Years to 80 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 3, 2026, 6:06 AM EDT
Recruiting No phase listed Observational

Cleaner Long-tErm Assessment Registry - Venous Insights and Efficacy With eXtended Tracking

NCT07102160
View directory record Official record
Conditions
Deep Vein Thrombosis (DVT), Thrombus in the Peripheral Venous Vasculature, Venous Embolism, Thrombus in the Central and Peripheral Circulatory System, Including Saphenous Vein Grafts
Interventions
Aspiration thrombectomy system
Device
Lead sponsor
Argon Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
Fort Lauderdale, Florida • Tampa, Florida • Edgewood, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional

THUNDER: Acute Ischemic Stroke Study With the Penumbra System® Including Thunderbolt™ Aspiration Tubing

NCT05437055
View directory record Official record
Conditions
Acute Ischemic Stroke, Large Vessel Occlusion
Interventions
Mechanical Thrombectomy (Penumbra System with Thunderbolt)
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
32
States / cities
Goodyear, Arizona • San Diego, California • Englewood, Colorado + 29 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Not listed Not applicable Interventional

EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial)

NCT05151172
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
endovascular thrombectomy (EVT), Standarad medical care
Device · Other
Lead sponsor
Dr. Michael D Hill
Other
Eligibility
18 Years and older
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
20
States / cities
Little Rock, Arkansas • San Francisco, California • Torrance, California + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational

Mild Acute Ischemic Stroke With Large Vessel Occlusion (MISTWAVE)

NCT03731351
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Mechanical Thrombectomy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Iowa City, Iowa • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional

A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX)

NCT05018650
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Route 92 Medical Reperfusion System
Device
Lead sponsor
Route 92 Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
29
States / cities
Mesa, Arizona • Carmichael, California • Newark, Delaware + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Distal Ischemic Stroke Treatment With Adjustable Low-profile Stentriever

NCT05152524
View directory record Official record
Conditions
Ischemic Stroke, Neovascularization
Interventions
Tigertriever 13
Device
Lead sponsor
Rapid Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
14
States / cities
Los Angeles, California • Thousand Oaks, California • Marietta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 3, 2026, 6:06 AM EDT
Completed No phase listed Observational

Registry of Emergent Large VeSsel OCclUsion DuE to IntraCranial AtherosclerosiS

NCT05403593
View directory record Official record
Conditions
Intracranial Stenosis, Large Vessel Occlusion, Mechanical Thrombectomy
Interventions
No Intervention
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
14
States / cities
New Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Sep 3, 2026, 6:06 AM EDT
Completed Phase 2 Interventional Results available

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial

NCT05172934
View directory record Official record
Conditions
Ischemic Stroke
Interventions
intra-arterial tenecteplase
Drug
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 3, 2026, 6:06 AM EDT