- Conditions
- Hypoplastic Left Heart Syndrome, Atrioventricular Canal
- Interventions
- MPC; rexlemestrocel-L
- Biological
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- Up to 5 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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Showing 1–11
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- Conditions
- Degenerative Disc Disease
- Interventions
- Rexlemestrocel-L, Rexlemestrocel-L + HA Mixture, Placebo
- Drug
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 404 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 47
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Scottsdale, Arizona + 42 more
- Conditions
- Type 2 Diabetes
- Interventions
- Mesenchymal Precursor Cells (MPCs)
- Drug
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 18
- States / cities
- Garden Grove, California • Miami, Florida • Orlando, Florida + 15 more
- Conditions
- Heart Failure
- Interventions
- Mesenchymal Precursor cells (RevascorTM), Cryoprotective media alone
- Biological · Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 17
- States / cities
- San Diego, California • Washington D.C., District of Columbia • Oak Lawn, Illinois + 12 more
- Conditions
- Myocardial Infarction
- Interventions
- Allogeneic Mesenchymal Precursor Cells (MPCs), Standard-of-care treatment with NOGA® mapping and staged injections.
- Genetic · Procedure
- Lead sponsor
- Angioblast Systems
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota • Houston, Texas
- Conditions
- Heart Failure, Cardiomyopathy, Ventricular Dysfunction
- Interventions
- MPC Intramyocardial injection, Control Solution
- Biological
- Lead sponsor
- Deborah Ascheim
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 11
- States / cities
- Gainsville, Florida • Baltimore, Maryland • Minneapolis, Minnesota + 8 more
- Conditions
- Heart Failure
- Interventions
- Mesenchymal Precursor Cells (MPCs), standard-of-care treatment with mock mapping and injection procedures.
- Biological · Procedure
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 20 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 6
- States / cities
- Gilbert, Arizona • La Jolla, California • Minneapolis, Minnesota + 3 more
- Conditions
- Heart Failure, Cardiomyopathy, Ventricular Dysfunction
- Interventions
- MPC Intramyocardial Injection, Control Solution
- Biological · Drug
- Lead sponsor
- Annetine Gelijns
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 159 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 16
- States / cities
- Los Angeles, California • Stanford, California • Baltimore, Maryland + 13 more
- Conditions
- Chronic Heart Failure
- Interventions
- Rexlemestrocel-L, Sham Comparator
- Biological · Other
- Lead sponsor
- Mesoblast, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 565 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 56
- States / cities
- Birmingham, Alabama • Gilbert, Arizona • Mesa, Arizona + 45 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Single Dose MPCs Injection, Single injection of saline solution, Single injection of hyaluronic acid
- Biological · Procedure
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 13
- States / cities
- Scottsdale, Arizona • Sacramento, California • Santa Monica, California + 10 more
- Conditions
- Rheumatoid Arthritis
- Interventions
- Allogeneic Mesenchymal Precursor Cells, Normal Saline
- Drug
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 20
- States / cities
- Anniston, Alabama • Gilbert, Arizona • El Cajon, California + 17 more