Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 11:14 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1801–1824 of 2,691 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Stroke, Brain Injuries, Spasticity
Interventions: Botox; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 12 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2010
U.S. locations: 2
States / cities: West Orange, New Jersey • Houston, Texas

Conditions: Breast Reconstruction, Breast Augmentation, Breast Revision
Interventions: Mentor Round Low Bleed Gel-filled Mammary Protheses, both Siltex and Smooth Surface; Device
Lead sponsor: Mentor Worldwide, LLC; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 1,008 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2012
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Achondroplasia
Interventions: BMN 111, Normal Saline; Drug
Lead sponsor: BioMarin Pharmaceutical; Industry
Eligibility: 22 Years to 45 Years · Male only
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: COVID-19
Interventions: Standard of care, Apremilast, Apremilast placebo, Lanadelumab, Lanadelumab placebo, Zilucoplan, Zilucoplan placebo; Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years and older
Enrollment: 515 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 21
States / cities: Anniston, Alabama • Bakersfield, California • Chula Vista, California + 17 more

Conditions: Stroke
Interventions: Ranitidine, Placebo, Advanced notification, No advanced notification; Drug · Other
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Clostridia Difficile Colitis, Clostridium; Sepsis
Interventions: Bezlotoxumab, Normal Saline; Biological · Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cardiovascular Abnormalities
Interventions: B12-Folic Acid, nitrous oxide, Nitrous oxide (NO) and placebo, Placebo, oxygen nitrogen; Drug · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Postoperative Pain, Total Knee Arthroplasty, Nerve Block
Interventions: bupivacaine, saline; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 40 Years to 85 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain
Interventions: Magnesium, Normal saline; Drug
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 4 Years to 10 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parturients
Interventions: Normal Saline, Administration of epidural anesthesia for labor; Other · Procedure
Lead sponsor: University of Medicine and Dentistry of New Jersey; Other
Eligibility: 18 Years to 45 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Major Depressive Disorder
Interventions: Ketamine, Scopolamine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Interventions: Hormone Replacement Therapy (HRT), Corticosteroid and 1%lidocain, physical therapy; Drug · Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 40 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Spasticity
Interventions: intramuscular Botox versus oral baclofen; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Ureteral Stent-Related Symptom
Interventions: Dexamethasone Sodium Phosphate Injection 20 mg, Dexamethasone Sodium Phosphate Injection 4mg; Drug
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years to 70 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Esophageal Cancer Surgery, Esophagectomy, Delayed Gastric Emptying Following Procedure, Esophageal Diseases, Esophageal Achalasia, Pylorus Dysfunction, Esophageal Dysmotility
Interventions: Botulinum Toxin A (Botox ), Pyloromyotomy; Biological · Procedure
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Respiratory Syncytial Virus
Interventions: Azithromycin 10 mg, Azithromycin 20mg, Placebo; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: Up to 16 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Trauma, Vascular System Injury
Interventions: Acellular Tissue Engineered Vessel (ATEV); Biological
Lead sponsor: Humacyte, Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 27
States / cities: La Jolla, California • Los Angeles, California • Orange, California + 18 more

Conditions: Glomerular Filtration Rate
Interventions: Lumitrace, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR); Device
Lead sponsor: MediBeacon; Industry
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Pleural Effusion, Single-ventricle
Interventions: Vasopressin, Normal Saline; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Months to 7 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Oak Lawn, Illinois

Conditions: Asthma
Interventions: Normal Saline, Albuterol; Drug
Lead sponsor: University Medical Center of Southern Nevada; Other
Eligibility: 18 Years to 70 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Dry Eye
Interventions: Artificial tears; Drug
Lead sponsor: Thomas O Salmon, OD, PhD; Other
Eligibility: 18 Years to 35 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Tahlequah, Oklahoma

Conditions: Surgical Incision, Pain, Postoperative, Pain, Acute
Interventions: Bupivacaine 0.25%, Normal Saline; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Glaucoma, Open-Angle
Interventions: Latanoprost 0.005%, Latanoprost bunod 0.024%, Normal saline 0.9%, Nailfold capillaroscopy; Drug · Diagnostic Test
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 40 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Urinary Retention
Interventions: Retained fluid, Emptied fluid; Procedure
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Phoenix, Arizona

Search by objective public record fields.

Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity

Core Gel Study of the Safety and Effectiveness of Mentor Round Low Bleed Silicone Gel-filled Mammary Prostheses

A Study to Evaluate Safety and Tolerability of BMN 111 Administered to Healthy Adult Volunteers

Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients

Extending Acute Stroke Trials to the Aerial Inter-hospital Transfer Setting

Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery.

Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia

US Guided GNB vs Saline Injection for TKA

Magnesium vs Placebo for Tonsillectomy

Study to Determine Whether the Instillation of 10ml Normal Saline Improves Epidural Analgesia During Labor

Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder

Frozen Shoulder and Hormone Replacement Therapy

Botox vs. Baclofen for Upper Limb Spasticity

Dexamethasone for Ureteral STent Symptoms (DUSTS)

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

Prospective Pilot Clinical Trial of Azithromycin Treatment In Respiratory Syncytial Virus (RSV)- Induced Respiratory Failure In Children

Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma

Evaluation of Protein Loading on Measurement of Renal Reserve

Use of Vasopressin Following the Fontan Operation

The Various Effects of Gaseous Albuterol on Serum Lactate

Tear Osmolarity Changes After Instilling Isotonic Hyaluronate Artificial Tears

Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision

Nailfold Capillary Blood Flow With Latanoprost Bunod

Post Hysterectomy Benefits of Retained Cystoscopy Fluid