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ClinicalTrials.gov public records Last synced Nov 5, 2026, 6:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1849–1872 of 2,691 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Cardiac Arrest
Interventions: Thiamine 500 mg IV, Placebo; Drug · Other
Lead sponsor: Michael Donnino; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Transient Severe Arterial Phase Motion
Interventions: gadoxetate disodium, gadoterate dimeglumine, Saline; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (Disorder)
Interventions: MBS-COV, Placebo; Drug · Other
Lead sponsor: Oneness Biotech Co., Ltd.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Anxiety
Interventions: CRANIAL ELECTROTHERAPY (Alpha Stim) + SHAM MIDAZOLAM, MIDAZOLAM + SHAM ELECTRODES SIMULATING CRANIAL ELECTROTHERAPY, NO SEDATION WITH SHAM CRANIAL ELECTROSTIMULATION AND PLACEBO VERSED; Device · Drug · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 50 Years to 90 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Cancer and Chemotherapy Related Anemia
Interventions: Injectafer, Normal Saline; Drug · Other
Lead sponsor: American Regent, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 244 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 29
States / cities: Corona, California • Fountain Valley, California • Riverside, California + 23 more

Conditions: Acute Ischemic Stroke, Cerebral Stroke
Interventions: Drug: Normal Saline, Sovateltide; Drug
Lead sponsor: Pharmazz, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 514 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 14
States / cities: Tucson, Arizona • Carmichael, California • Oxnard, California + 10 more

Conditions: Heart Transplant
Interventions: tocilizumab, Placebo, Standard of Care Triple IS; Biological · Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 75 Years
Enrollment: 385 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 20
States / cities: Beverly Hills, California • La Jolla, California • Stanford, California + 15 more

Conditions: Vomiting, Nausea, Children, Only
Interventions: Inhaled Isopropyl Alcohol, Oral Ondansetron, Inhaled Placebo; Other · Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 7 Years to 17 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Femoral Neck Fractures
Interventions: Tranexamic Acid, Placebo (saline); Drug
Lead sponsor: UConn Health; Other
Eligibility: 55 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Farmington, Connecticut • Hartford, Connecticut

Conditions: Obesity
Interventions: benzocaine, placebo; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 20 Years to 50 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Vitamin C Deficiency, Smoking, Surgery, Surgery--Complications, Wound, Wound Complication, Wound Infection, Wound Dehiscence, Wound of Skin, Mandible Fracture, Mandible Open Fracture, Mandible Closed Fracture, Mandibular Fractures, Ascorbic Acid Deficiency, Oxidative Stress, Inflammation
Interventions: Vitamin C, Placebo; Dietary Supplement · Other
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Abscess
Interventions: Standard of Care (SoC), Irrisept Delivery System; Device
Lead sponsor: Irrimax Corporation; Industry
Eligibility: 12 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Acute Liver Failure, Fulminant Hepatic Failure, Hepatic Encephalopathy, Acute Liver Injury, Immune Dysregulation
Interventions: High-dose methylprednisolone, Equine anti-thymocyte globulin, Prednisolone, Placebo for prednisolone, Placebo for infusions, Diphenhydramine, Methylprednisolone; Drug
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 1 Year to 18 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 17
States / cities: Los Angeles, California • Palo Alto, California • San Diego, California + 14 more

Conditions: Pregnancy, Prolonged
Interventions: Propranolol Hydrochloride, Saline; Drug · Other
Lead sponsor: Lisa Levine; Other
Eligibility: 16 Years and older · Female only
Enrollment: 164 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
Interventions: TTAX03, Saline; Biological
Lead sponsor: BioTissue Holdings, Inc; Industry
Eligibility: 35 Years to 85 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 10
States / cities: Birmingham, Alabama • Tucson, Arizona • La Mesa, California + 6 more

Conditions: Forehead Rhytides, Glabellar Rhytides
Interventions: OnabotulinumtoxinA, Normal Saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 421 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 9
States / cities: Birmingham, Alabama • Glendale, Arizona • Santa Monica, California + 6 more

Conditions: Bacterial Infections
Interventions: QPX9003 for IV Infusion, Placebo for IV infusion; Drug
Lead sponsor: Qpex Biopharma, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Cypress, California

Conditions: Hyperuricemia
Interventions: Rasburicase, Placebo; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Primary Systemic (AL) Amyloidosis
Interventions: NEOD001, Placebo; Drug · Other
Lead sponsor: Prothena Biosciences Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 32
States / cities: Scottsdale, Arizona • Duarte, California • Stanford, California + 26 more

Conditions: Pelvic Organ Prolapse
Interventions: IV Acetaminophen, IV normal saline; Drug
Lead sponsor: Halina M Zyczynski, MD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hepatorenal Syndrome, Acute Kidney Injury
Interventions: R2R01, Terlipressin; Drug
Lead sponsor: River 2 Renal Corp.; Industry
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 7
States / cities: San Francisco, California • Atlanta, Georgia • Boston, Massachusetts + 4 more

Conditions: Alzheimer Dementia, Late Onset Alzheimer Disease, Neurodegenerative Diseases
Interventions: Allopregnanolone, Placebo; Drug · Other
Lead sponsor: University of Arizona; Other
Eligibility: 55 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 9
States / cities: Scottsdale, Arizona • Tucson, Arizona • Costa Mesa, California + 5 more

Conditions: Urinary Tract Infection, Antibiotic, Catheter Infection
Interventions: 0.05% Chlorhexidine Gluconate, Normal Saline; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Pediatric Lumbar Puncture
Interventions: Normal Saline Intravenous Fluids; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 0 Months to 3 Months
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Birmingham, Alabama

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Thiamine as a Metabolic Resuscitator After Cardiac Arrest

Eovist vs. Dotarem Healthy Volunteer MRI

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled MBS-COV (SNS812) in Healthy Participants

Cranial Electro Therapy Stimulation in Reducing Perioperative Anxiety

Can Iron Lessen Anemia Due to Cancer and Chemotherapy: A Study to Investigate the Efficacy and Safety of Injectafer®

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Tocilizumab in Cardiac Transplantation

Inhaled Isopropyl Alcohol for Treatment of Nausea

Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty

Role of the Foregut in Nutrient Metabolism in Lean and Obese Humans

The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients

The Effect of Wound Irrigation With Irrisept on Abscess Healing (Irrisept UF Study)

TReatment for ImmUne Mediated PathopHysiology

Propranolol Rescue of Prolonged Labor

Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA

A Safety and Efficacy Study of OnabotulinumtoxinA in Forehead and Glabellar Facial Rhytides

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers

Lowering Serum Uric Acid to Prevent Acute Kidney Injury

The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis

IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.

Intravenous Fluid Administration's Effect on Pediatric Lumbar Puncture