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ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:17 AM EDT

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Showing 97–120 of 584 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: OCT Clear all
Terminated No phase listed Observational

Real Time Optical Coherence Tomography (OCT) of Human Tissue

NCT01506700
View directory record Official record
Conditions
Breast Cancer
Interventions
Optical Coherence Tomography
Device
Lead sponsor
Diagnostic Photonics, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2019 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

OCT Agreement and Precision Study

NCT02045823
View directory record Official record
Conditions
Normal Eyes, Eyes With Glaucoma, Eyes With Retinal Disease
Interventions
Not listed
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Jamaica, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Data Collection Study of the Nidek Optical Coherence Tomography RS-3000 for 3D Measurements of the Eye

NCT01663688
View directory record Official record
Conditions
Ocular Physiology
Interventions
Not listed
Lead sponsor
Nidek Co. LTD.
Industry
Eligibility
20 Years and older
Enrollment
279 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
3
States / cities
La Jolla, California • Los Angeles, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2014 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational

Comparison of Two OCT Device RNFL and GCIPL Measurements in Mild, Moderate, and Severe Glaucoma

NCT07350304
View directory record Official record
Conditions
Glaucoma
Interventions
Optical Coherence Tomography
Diagnostic Test
Lead sponsor
Twin Cities Eye Consultants
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Coon Rapids, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 19, 2026, 1:17 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

The Significance of Glucose Intolerance in the Pathogenesis of Idiopathic Axonal Polyneuropathy

NCT00228345
View directory record Official record
Conditions
Idiopathic Axonal Polyneuropathy, Abnormal OGTT
Interventions
Optical coherence tomography,Fluorescein angiography
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
50 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 19, 2026, 1:17 AM EDT
Completed Phase 3 Interventional

A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

NCT04504812
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Duloxetine, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices
Drug · Combination Product · Procedure + 2 more
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
1,937 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
24
States / cities
Sacramento, California • San Diego, California • Aurora, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 19, 2026, 1:17 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation

NCT03224299
View directory record Official record
Conditions
Preoperative Skin Preparation
Interventions
OCT - clear, OCT- tinted, ChloraPrep, Saline
Drug · Other
Lead sponsor
Becton, Dickinson and Company
Industry
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
Bozeman, Montana • Butte, Montana
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 19, 2026, 1:17 AM EDT
Completed Phase 2 Interventional

An OCT-Guided Variable Dosing Regimen With Ranibizumab for the Treatment of Neovascular AMD

NCT00373659
View directory record Official record
Conditions
Neovascular Age-related Macular Degeneration
Interventions
Ranibizumab (Lucentis)
Drug
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Oct 19, 2026, 1:17 AM EDT
Completed Not applicable Interventional Results available

Optical Frequency Domain Imaging (OFDI) for Biliary Stricture Imaging

NCT01439620
View directory record Official record
Conditions
Biliary Stricture
Interventions
MGH Optical Frequency Domain Imaging (OFDI)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 19, 2026, 1:17 AM EDT
Recruiting No phase listed Observational

Scleral Lens Fitting Using Wide-Field OCT

NCT04570020
View directory record Official record
Conditions
Keratoconus, Irregular; Contour of Cornea
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 19, 2026, 1:17 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety and Efficacy of Ranibizumab for Diabetic Macular Edema

NCT01982435
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Ranibizumab
Drug
Lead sponsor
Justis Ehlers
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Cleveland, Ohio • Mayfield Heights, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Topcon 3D OCT-1 Maestro Reference Database Study II

NCT02447120
View directory record Official record
Conditions
Healthy
Interventions
3D OCT-1 Maestro
Device
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
504 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
7
States / cities
Birmingham, Alabama • Fullerton, California • Livermore, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Objective Assessment of Intraocular Lens Tilt and Decentration

NCT07324200
View directory record Official record
Conditions
Tilt and Decentration
Interventions
OCT Imaging Test
Diagnostic Test
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Bakersfield, California • Sioux City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational

Macular Ganglion Cell Analysis (GCA) of the Cirrus HD-OCT in Glaucoma

NCT01272102
View directory record Official record
Conditions
Glaucoma
Interventions
Not listed
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
40 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
4
States / cities
Palo Alto, California • Miami, Florida • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2013 · Synced Oct 19, 2026, 1:17 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

NCT04565821
View directory record Official record
Conditions
Inflammatory Disease, Permeability; Increased, Crohn Disease, Inflammatory Bowel Diseases, Environmental Enteropathy
Interventions
IPD Probe via TNIT
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 19, 2026, 1:17 AM EDT
Recruiting Not applicable Interventional

OCT Eccentric Fixation and Amblyopia in Children

NCT05714449
View directory record Official record
Conditions
Amblyopia
Interventions
eye patch, After-image and MIT trainer
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
4 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 19, 2026, 1:17 AM EDT
Not listed No phase listed Observational

Evaluation of Repeated, In-Clinic, Self-Imaging by DME Patients Using the Notal Vision Home OCT

NCT05745116
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Notal Vision Home OCT
Device
Lead sponsor
Notal Vision Inc.
Industry
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Baltimore, Maryland • Fairfax, Virginia • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 19, 2026, 1:17 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

NCT07065747
View directory record Official record
Conditions
Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus, Juvenile Idiopathic Arthritis (JIA), Spondyloarthritis (SA), Sarcoidosis, Posterior Vitreous Detachment
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
5 Years to 85 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 19, 2026, 1:17 AM EDT
Withdrawn No phase listed Observational

Optical Coherence Tomography of the Airway for Lung Cancer or Lung Disease

NCT00733252
View directory record Official record
Conditions
Lung Cancer, Malignant Mesothelioma, Metastatic Cancer, Nonmalignant Neoplasm, Precancerous Condition
Interventions
bronchoscopic and lung imaging studies, diagnostic bronchoscopy, histopathologic examination, optical coherence tomography
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Oct 19, 2026, 1:17 AM EDT
Terminated Not applicable Interventional

Intraoperative Use of an Optical Coherence Tomography (OCT) Imaging System to Guide Additional Margin Cavity Shaves in Breast Conserving Surgery (BCS)

NCT04314700
View directory record Official record
Conditions
Breast Cancer Female
Interventions
OCT- based investigational imaging device
Device
Lead sponsor
Perimeter Medical Imaging
Industry
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cottonwood, Arizona
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 19, 2026, 1:17 AM EDT
Completed No phase listed Observational

Retrospective Study of the Safety and Efficacy of Patients With RVO in Subjects Who Completed Parent Study CLS1003-201

NCT02956330
View directory record Official record
Conditions
Macular Edema, Retinal Vein Occlusion
Interventions
Not listed
Lead sponsor
Clearside Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 20, 2019 · Synced Oct 19, 2026, 1:17 AM EDT
Completed Not applicable Interventional

Drug Eluting Stent for the Management of PERipheral Arterial Disease Of the SFA (DESPERADO-SFA Study)

NCT02734836
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Balloon Angioplasty, Optical Coherence Tomography
Device · Other
Lead sponsor
Arkansas Heart Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Oct 19, 2026, 1:17 AM EDT
Recruiting Not applicable Interventional

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

NCT05701358
View directory record Official record
Conditions
Acute Myocardial Infarction, Coronary Artery Disease
Interventions
Physiology-guided NCL PCI, Angiography-guided NCL PCI
Procedure
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Wichita, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 19, 2026, 1:17 AM EDT
Not yet recruiting No phase listed Observational

Intraoperative Optical Coherence Tomography for Ophthalmic Surgical Guidance - Cornea

NCT05210478
View directory record Official record
Conditions
Corneal Transplantation
Interventions
Optical coherence tomography (OCT)
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Timeline
2027 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 19, 2026, 1:17 AM EDT