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ClinicalTrials.gov public records Last synced Sep 11, 2026, 1:28 PM EDT

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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Onyx Clear all
Active, not recruiting Not applicable Interventional

Firehawk Rapamycin Target Eluting Coronary Stent North American Trial

NCT04562532
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Microport Firehawk stent, 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent)
Device
Lead sponsor
Shanghai MicroPort Medical (Group) Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
1,720 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
44
States / cities
Birmingham, Alabama • Gilbert, Arizona • La Jolla, California + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Sep 11, 2026, 1:28 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Phase 1b/2, Multicenter, Open-label Study of Oprozomib and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma

NCT01832727
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Oprozomib, Dexamethasone
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
10
States / cities
Los Angeles, California • Tampa, Florida • Westwood, Kansas + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2020 · Synced Sep 11, 2026, 1:28 PM EDT
Not yet recruiting Not applicable Interventional

MMA Embolization With NeoCast for Subacute and Chronic Subdural Hematoma

NCT07541404
View directory record Official record
Conditions
Subdural Hematoma
Interventions
NeoCast Embolic System, Onyx LES, an FDA-Approved Commercial Liquid Embolic
Device
Lead sponsor
Arsenal Medical, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
New Haven, Connecticut • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional

Safety of Apollo Micro Catheter in Pediatric Patients

NCT02085278
View directory record Official record
Conditions
Brain Arteriovenous Malformation, Brain Vascular Malformations, Vein of Galen Malformation
Interventions
Apollo Micro Catheter device
Device
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
Up to 21 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)

NCT03584464
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
Device
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
21
States / cities
Huntsville, Alabama • La Jolla, California • Riverside, California + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Medtronic RESOLUTE ONYX Core (2.25 mm - 4.0 mm) Clinical Study

NCT02419521
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Resolute Onyx Stent - 2.25 mm - 4.0 mm
Device
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
12
States / cities
La Jolla, California • Clearwater, Florida • Springfield, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Active, not recruiting Not applicable Interventional

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

NCT05268094
View directory record Official record
Conditions
Congenital Heart Disease in Children
Interventions
Ductal Arterial Stent, Systemic-to-Pulmonary Artery Shunt
Device · Procedure
Lead sponsor
Carelon Research
Other
Eligibility
1 Day to 30 Days
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
23
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

A Single Arm Trial With Resolute Onyx in ONE-Month DAPT for High-Bleeding Risk Patients Who Are Considered One-Month Clear (Onyx ONE Clear)

NCT03647475
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Device: Medtronic Resolute Onyx Zotarolimus-Eluting Coronary Stent System Treatment Followed by one-month DAPT
Combination Product
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
752 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
4
States / cities
East Syracuse, New York • New York, New York • Anderson, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Evaluation of an Ascensia Diabetes Care ONYX PLUS Investigational Blood Glucose Monitoring System

NCT02371876
View directory record Official record
Conditions
Diabetes
Interventions
ONYX PLUS Investigational Blood Glucose Monitoring System
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
2
States / cities
Escondido, California • Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Active, not recruiting Not applicable Interventional

IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact

NCT04221815
View directory record Official record
Conditions
Atherosclerosis
Interventions
Eagle Eye Platinum digital IVUS catheter with optional SyncVision, Resolute Onyx Drug Eluting Stent, Onyx Frontier Drug Eluting Stent, Onyx TruStar Drug Eluting Stent, Onyx TruCor Drug Eluting Stent
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
40
States / cities
Tucson, Arizona • Little Rock, Arkansas • La Jolla, California + 36 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Evaluation of an Ascensia Diabetes Care Blood Glucose Meter and App System

NCT03165110
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Onyx BG Meter / App System
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
18 Years to 75 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Phase 2 Interventional Results available

Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma

NCT00511238
View directory record Official record
Conditions
Multiple Myeloma
Interventions
carfilzomib
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
28
States / cities
Mobile, Alabama • Scottsdale, Arizona • Beverly Hills, California + 23 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Evaluation of an Ascensia Blood Glucose Meter and App System

NCT02568384
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Onyx BG Meter / App System
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
18 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Ascensia ONYX NEXT Investigational Blood Glucose Monitoring System

NCT02390167
View directory record Official record
Conditions
Diabetes
Interventions
ONYX NEXT BGMS
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
Escondido, California • Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Medtronic Resolute Onyx 2.0 mm Clinical Study

NCT02412501
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Resolute Onyx Stent - 2.0 mm
Device
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
17
States / cities
La Jolla, California • Clearwater, Florida • Springfield, Illinois + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Recruiting Not applicable Interventional

Onyx™ Liquid Embolic IDE Clinical Study

NCT06742801
View directory record Official record
Conditions
Peripheral Arterial Hemorrhage, Trauma, GI Bleed, Ulcer, Hemorrhage
Interventions
Onyx™ Liquid Embolic System
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
22 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
19
States / cities
Phoenix, Arizona • Irvine, California • Palo Alto, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 11, 2026, 1:28 PM EDT
Not yet recruiting Not applicable Interventional

Comparative Study of Embolic Agents in Patients With Subdural Hemorrhage Undergoing Middle Meningeal Artery (MMA) Embolization

NCT07757113
View directory record Official record
Conditions
Chronic Subdural Hematoma, Stroke, Middle Meningeal Artery Embolization
Interventions
Particles (polyvinyl alcohol or similar microspheres), Liquid Embolics (Onyx, n-BCA, or equivalent), Phenox Coils (Avenir UNO Helical Coil)
Device
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Apollo™ Onyx™ Delivery Microcatheter Post Market Safety Study

NCT02378883
View directory record Official record
Conditions
Arteriovenous Malformations
Interventions
Apollo™ Onyx™ Delivery Micro Catheter
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
Not listed
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Englewood, Colorado • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2019 · Synced Sep 11, 2026, 1:28 PM EDT
Completed No phase listed Observational

RESOLUTE ONYX Post-Approval Study

NCT03063749
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
Device
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
23
States / cities
Huntsville, Alabama • La Jolla, California • Riverside, California + 19 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

NCT02100722
View directory record Official record
Conditions
Coronary Disease, Coronary Stenosis
Interventions
FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
13
States / cities
Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Effect of Onyx Sorghum on Blood Glucose in Individuals With Type 2 Diabetes

NCT03714451
View directory record Official record
Conditions
Diabetes Type 2
Interventions
onyx sorghum, whole wheat flour
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
30 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Phase 2 Interventional

Study Comparing Onyx and TRUFILL in Brain Arteriovenous Malformations (AVMs)

NCT00857662
View directory record Official record
Conditions
Brain Arteriovenous Malformations
Interventions
Onyx, TRUFILL
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
Not listed
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Sep 11, 2026, 1:28 PM EDT
Recruiting Not applicable Interventional

Bilateral Embolization of the Middle Meningeal Arteries for Refractory Chronic Migraine

NCT07223008
View directory record Official record
Conditions
Migraine, Chronic Migraine Headache, Refractory Migraine
Interventions
embolization of middle meningeal arteries
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 11, 2026, 1:28 PM EDT
Completed Not applicable Interventional

Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma

NCT04402632
View directory record Official record
Conditions
Subdural Hematoma
Interventions
Surgical Management, Onyx™ Liquid Embolic System (LES) Embolization, Observation Only
Procedure · Device · Other
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
18 Years to 90 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
49
States / cities
Birmingham, Alabama • Tucson, Arizona • Irvine, California + 44 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 11, 2026, 1:28 PM EDT